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of 9
pro vyhledávání: '"Kinan, Mokbel"'
Autor:
Jajini Varghese, Neill Patani, Umar Wazir, Shonnelly Novintan, Michael J. Michell, Anmol Malhotra, Kinan Mokbel, Kefah Mokbel
Publikováno v:
Cancers, Vol 16, Iss 12, p 2172 (2024)
Recent advances in neoadjuvant systemic therapy (NST) have significantly improved pathologic complete response rates in early breast cancer, challenging the role of axillary lymph node dissection in nose-positive patients. Targeted axillary dissectio
Externí odkaz:
https://doaj.org/article/cbcc1ec37e5f4485b25294a6765555dd
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 10, p 2908 (2024)
Background/Objectives: De-escalation of axillary surgery is made possible by advancements in both neoadjuvant systemic therapy (NST) and in localisation technology for breast lesions. Magseed®, developed in 2013 by Dr. Michael Douk of Cambridge, Uni
Externí odkaz:
https://doaj.org/article/2887e918168643de99227393b8bc77df
Publikováno v:
Cancers, Vol 16, Iss 4, p 742 (2024)
Complete axillary lymph node dissection (cALND) was previously the standard of care for breast cancer (BC) patients with axillary node disease or macro-metastases found via sentinel lymph node biopsy (SLNB). However, due to significant morbidity, con
Externí odkaz:
https://doaj.org/article/09306e074033431b9485adebab6b136d
Publikováno v:
Cancers, Vol 15, Iss 13, p 3325 (2023)
Recent advances in systemic treatment for breast cancer have been underpinned by recognising and exploiting subtype-specific vulnerabilities to achieve higher rates of pathologic complete response (pCR) after neo-adjuvant systemic therapy (NAST). Thi
Externí odkaz:
https://doaj.org/article/18d56db5b7e74002b1437272c1293e57
Publikováno v:
Cellular & Molecular Biology Letters, Vol 22, Iss 1, Pp 1-7 (2017)
Abstract Background Clinicians use clinical and pathological parameters, such as tumour size, grade and nodal status, to make decisions on adjuvant treatments for breast cancer. However, therapeutic decisions based on these features tend to vary due
Externí odkaz:
https://doaj.org/article/276adae003734742a38f5443376b14bc
Publikováno v:
Anticancer Research. 42:1013-1018
Improvements in acellular dermal matrix (ADM) and surgical techniques have facilitated pre-pectoral immediate breast reconstruction (IBR). Outer shell texturing is a key risk factor for anaplastic large cell lymphoma, prompting this evaluation of rec
Autor:
Kinan, Mokbel, Kefah, Mokbel
Publikováno v:
Anticancer Research. 42:661-666
Breast cancer is the most common cancer in women globally. To prevent relapse and prolong disease-free survival, adjuvant endocrine treatment such as selective oestrogen receptor modulators and aromatase inhibitors are being used. However, such oestr
Publikováno v:
In Vivo
Background/Aim: Adverse drug reactions (ADRs) represent a major concern leading to significant increases in both morbidity and mortality globally. Providing healthcare professionals (HCPs) and patients with real-world data on drug safety is imperativ
Publikováno v:
Anticancer research. 38(8)
The Nottingham Prognostic Index (NPI) was developed using tumour pathological features to guide decisions regarding adjuvant therapy in breast cancer. Recent breakthroughs in molecular biology aided development of genomic assays such as EndoPredict,