Výsledky vyhledávání

SAR103168, a tyrosine kinase inhibitor of the pyrido [2,3-d] pyridimidine subclass, inhibited the kinase activities of the entire Src kinase family, Abl kinase, angiogenic receptor kinases (vascular endothelial growth factor receptor [VEGFR] 1 and 2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f827ba20e6843fcf5db491dbdeed409
https://doi.org/10.3109/10428194.2012.745071

Zobrazit plný text záznamu

Abstract 1135: Chemical Proteomics effort identifies PKN1 as a key player in the canonical NF-κB signaling pathway

Autor: Christoph Lengauer, Kin T. Yu, Brittain Scott, Marion Dorsch, Ronald Tomlinson, Francisco Adrian, Katherine Tang, Tieu-Binh Le, Ivan Cornella-Taracido, Carlos Garcia-Echeverria, Mikhail Levit, Lakshmi Srinivasan, Michael Lampa, Matthieu Barrague, Balin Zhang, Hong Cheng, Tahir Majid

Publikováno v: Cancer Research. 73:1135-1135

Deregulation of NF-κB signaling pathway has been identified as one of the key drivers of many hematological malignancies. Activation of the NF-κB pathway in these cells can happen either through activating mutations within the pathway, loss of func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b47e870f98ba5afc801c6d3bbbb33e4
https://doi.org/10.1158/1538-7445.am2013-1135

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání