Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Kin Ming, Kwan"'
Autor:
Pallavi Asthana, Gajendra Kumar, Lukasz M. Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K. Wszolek, Chi Him Eddie Ma
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-19 (2022)
Abstract Peripheral nerve injury (PNI) often results in spontaneous motor recovery; however, how disrupted cerebellar circuitry affects PNI-associated motor recovery is unknown. Here, we demonstrated disrupted cerebellar circuitry and poor motor reco
Externí odkaz:
https://doaj.org/article/3b2eeb318d0e4288b3702b110a4ba585
Autor:
Chenguang Wang, Yalan Wu, Yangxian Li, Yang Zhang, Yee Lok Fung, Ka Kui Tong, Chi Wai Lau, Li Xiang, Kin Ming Kwan, Li-Ru You, Yu Huang, Xiao Yu Tian
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106272- (2023)
Summary: Beige adipocytes are thermogenic with high expression of uncoupling protein 1 in the white adipose tissue (WAT), accompanied by angiogenesis. Previous studies showed that Smad4 is important for angiogenesis. Here we studied whether endotheli
Externí odkaz:
https://doaj.org/article/35b22b0f509546ea808cab8d3da53e52
Autor:
Xiaonan Dong, Kin Ming Kwan
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract The highly conserved and ubiquitously expressed transcription factor Yin Yang 1 (Yy1), was named after its dual functions of both activating and repressing gene transcription. Yy1 plays complex roles in various fundamental biological process
Externí odkaz:
https://doaj.org/article/c7605c5ca37846d3962df58147300adf
Autor:
Hei‐Man Chow, Jacquelyne Ka‐Li Sun, Ronald P. Hart, Kenneth King‐Yip Cheng, Clara H. L. Hung, Tsun‐Ming Lau, Kin‐Ming Kwan
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract Early changes in astrocyte energy metabolism are associated with late‐onset Alzheimer's disease (LOAD), but the underlying mechanism remains elusive. A previous study suggested an association between a synonymous SNP (rs1012672, C→T) in
Externí odkaz:
https://doaj.org/article/20179694e8944d0e88c9468969d8d620
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3616-3624.e4 (2020)
Summary: Neural progenitors undergo temporal fate transition to generate diversified neurons in stereotyped sequence during development. However, the molecular machineries driving progenitor fate change remain unclear. Here, using the cerebellum as a
Externí odkaz:
https://doaj.org/article/e489aaa6ff0f4fef9a5c5309636b077e
Autor:
Nga Chu Lui, Wing Yip Tam, Caiji Gao, Jian-Dong Huang, Chi Chiu Wang, Liwen Jiang, Wing Ho Yung, Kin Ming Kwan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Purkinje cells (PCs) receive signals from different inputs through their extensively branched dendrites and dysregulation of this process leads to ataxia and other diseases. Here the authors show that the LIM-homeodomain transcription factors Lhx1 an
Externí odkaz:
https://doaj.org/article/48c6986ca9f3427294ec05c869483932
Autor:
Jacquelyne Ka‐Li Sun, Deng Wu, Genper Chi‐Ngai Wong, Tsun‐Ming Lau, Meigui Yang, Ronald P. Hart, Kin‐Ming Kwan, Ho Yin Edwin Chan, Hei‐Man Chow
Publikováno v:
Aging Cell. 22
Publikováno v:
Molecular neurobiology. 59(7)
Cerebellum is one of the major targets of autoimmunity and cerebellar damage that leads to ataxia characterized by the loss of fine motor coordination and balance, with no treatment available. Deep brain stimulation (DBS) could be a promising treatme
Autor:
Chenguang Wang, Yalan Wu, Yang Zhang, Yee Lok Fung, Ka Kui Tong, Chi Wai Lau, Li Xiang, Kin Ming Kwan, Li-Ru You, Yu Huang, Xiao Yu Tian
Publikováno v:
SSRN Electronic Journal.
Autor:
Pui-Wah Choi, Dale B. Hales, Kin Ming Kwan, William R. Welch, Shu-Kay Ng, Ross S. Berkowitz, Jamie S. L. Kwok, Karen Hales, Junzheng Yang, Ka Kui Tong, Shubai Liu, Shu-Wing Ng, Wing-Ping Fong, Christopher P. Crum, Stephen Kwok-Wing Tsui, Wai Wing So
Publikováno v:
Oncogene. 39:4045-4060
Epidemiologic and histopathologic findings and the laying hen model support the long-standing incessant ovulation hypothesis and cortical inclusion cyst involvement in sporadic ovarian cancer development. MicroRNA-200 (miR-200) family is highly expre