Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Kin Man Loke"'
1
Akademický článek
Enhanced anti-tumor efficacy with multi-transgene armed mesenchymal stem cells for treating peritoneal carcinomatosis
Autor: Yoon Khei Ho, Jun Yung Woo, Kin Man Loke, Lih-Wen Deng, Heng-Phon Too
Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Mesenchymal stem cells (MSCs) have garnered significant interest for their tumor-tropic property, making them potential therapeutic delivery vehicles for cancer treatment. We have previously shown the significant anti-tumour activ
Externí odkaz: https://doaj.org/article/1c3ef94756d04a3982f8cabf16117a44
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2
Akademický článek
Cryopreservation does not change the performance and characteristics of allogenic mesenchymal stem cells highly over-expressing a cytoplasmic therapeutic transgene for cancer treatment
Autor: Yoon Khei Ho, Kin Man Loke, Jun Yung Woo, Yee Lin Lee, Heng-Phon Too
Publikováno v: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Background Mesenchymal stem cells (MSCs) driven gene directed enzyme prodrug therapy is a promising approach to deliver therapeutic agents to target heterogenous solid tumours. To democratize such a therapy, cryopreservation along with cold
Externí odkaz: https://doaj.org/article/44027414170f4f3fbcc0f4f1f2f8e1db
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5
Data from Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion
Autor: Darren Reece Williams, Da-Woon Jung, Jung-Joon Min, Jin Kim, Hyunju Lee, Hyoen Sik Kim, Jihee Soh, Jun-Hyeong Kim, Seong-Min Oh, Seon-Wook Kim, Kin Man Loke, Youngha Seo, Haaglim Cho
Purpose: M2-type TAMs are increasingly implicated as a crucial factor promoting metastasis. Numerous cell types dictate monocyte differentiation into M2 TAMs via a complex network of cytokine-based communication. Elucidating critical pathways in this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b08b15cd11753c15e334a93101d67dd
https://doi.org/10.1158/1078-0432.c.6529023
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8
Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion
Autor: Seon-Wook Kim, Kin Man Loke, Youngha Seo, Jun-Hyeong Kim, Hyoen Sik Kim, Hyunju Lee, Da-Woon Jung, Jung-Joon Min, Jin Kim, Jihee Soh, Haaglim Cho, Darren R. Williams, Seong-Min Oh
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 24(21)
Purpose: M2-type TAMs are increasingly implicated as a crucial factor promoting metastasis. Numerous cell types dictate monocyte differentiation into M2 TAMs via a complex network of cytokine-based communication. Elucidating critical pathways in this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f011f3b75a0dda1e8742a41150e07d68
https://pubmed.ncbi.nlm.nih.gov/30647086
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