Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kin Fai Cheung"'
Autor:
Kwong Wai Choy, Tom C. Lee, Kin Fai Cheung, Dorothy S.P. Fan, Kwok Wai Lo, Katherine L. Beaverson, David H. Abramson, Dennis S.C. Lam, Christopher B.O. Yu, Chi Pui Pang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 3, Pp 200-206 (2005)
We investigated the epigenetic silencing and genetic changes of the RAS-associated domain family 1A (RASSF1A) gene and the Os-methylguanine-DNA methyltransferase (MGMT) gene in retinoblastoma. We extracted DNA from microdissected tumor and normal ret
Externí odkaz:
https://doaj.org/article/a4acee07f567413ea0560820d1a620b8
Autor:
Anson W. Lowe, Kin-Fai Cheung, Junhong Zhao, Alfred S. L. Cheng, Xiaoxing Li, Ying Hao, Joseph J.Y. Sung, Jun Yu
Publikováno v:
Cancer. 119:1217-1226
BACKGROUND: Previous reports from these authors found that activation of peroxisome proliferator-activated receptor gamma (PPARγ) suppressed hepatocellular carcinoma (HCC). This study sought to identify the molecular target of PPARγ and characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e61a48d6f85ce0bc4b0de9b570870173
https://doi.org/10.1002/cncr.27865
https://doi.org/10.1002/cncr.27865
Autor:
Joseph J.Y. Sung, Kin-Fai Cheung, Wei Kang, Junhong Zhao, Jun Yu, Qiaoyi Liang, Joanna H.M. Tong, Ka Fai To, Raymond W.M. Lung
Publikováno v:
Cancer. 119:304-312
BACKGROUND: Aberrant methylation of tumor-related genes has been reported in Epstein-Barr virus (EBV)-associated gastric cancers. This study sought to profile EBV-driven hypermethylation in EBV-infected cells. METHODS: The EBV-positive AGS gastric ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3883275667e1e3f726a9c98fa39be273
https://doi.org/10.1002/cncr.27724
https://doi.org/10.1002/cncr.27724
Autor:
Jianming Ying, Kin-Fai Cheung, Linwei Tian, Hsiang-Fu Kung, Alfred S. L. Cheng, Junhong Zhao, Bo Shen, Jun Yu, Xiaowei Ma, Xiaoxing Li, Joseph J.Y. Sung, Minnieyy Go, Qian Tao
Publikováno v:
Oncogene. 31:3419-3430
Using genome-wide methylation screening, we identified that paired box gene 5 (PAX5) is involved in human cancer development. However, the function of PAX5 in gastric cancer (GC) development is largely unclear. We analyzed its epigenetic inactivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7016b433606529848c931d62f13fdd3
https://doi.org/10.1038/onc.2011.511
https://doi.org/10.1038/onc.2011.511
Autor:
Hongchuan Jin, Sui Zhang, Junhong Zhao, Kin Fai Cheung, Patrick Leung, Wei Kang, Ka Fai To, Jun Yu, Xiaoxing Li, Zhirong Zeng, Linwei Tian, Joanna H.M. Tong, Joseph J.Y. Sung, Minnie Y.Y. Go
Publikováno v:
Cancer. 118:924-936
BACKGROUND: The role of Epstein-Barr virus (EBV) infection in gastric carcinogenesis remains largely unknown. The authors studied the effects of zinc finger E-box binding factor 1 (ZEB1) on latent-lytic switch of EBV infection in gastric cancer and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015768b8a6978b31630dcb70b3918987
https://doi.org/10.1002/cncr.26184
https://doi.org/10.1002/cncr.26184
Autor:
Alfred S. L. Cheng, Kin-Fai Cheung, Joseph J.Y. Sung, Daiming Fan, Ka Fai To, Kaichun Wu, Wilson W. S. Chong, Jun Yu, Enders K.O. Ng, Cleo N.Y. Lam
Publikováno v:
Cancer. 118:947-959
BACKGROUND: By using genome-wide methylation screening, the authors identified ring finger protein 180 (RNF180) as preferentially methylated in cancer. This study was undertaken to clarify its structure and functional role in gastric cancer. METHODS:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70ae8957576acfc270a04ad3f172e13c
https://doi.org/10.1002/cncr.26189
https://doi.org/10.1002/cncr.26189
Autor:
Nathalie Wong, Tim H M Huang, Hongchuan Jin, Hoi K. Wong, Yangchao Chen, Yutaka Kondo, Kwong Wai Choy, Jun Yu, Kin Fai Cheung, Hai Feng, Suki S. Lau, Arthur K.K. Ching, May S. Li, Joanna H.M. Tong, Joseph J.Y. Sung, Alfred S. L. Cheng, Ka F. To
Publikováno v:
Cancer Research. 71:4028-4039
Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the Polycomb-repressive complex 2 (PRC2) that represses gene transcription through histone H3 lysine 27 trimethylation (H3K27me3). Although EZH2 is abundantly present in various cancers,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565fa14e5222bf9974eefe85435bf7fa
https://doi.org/10.1158/0008-5472.can-10-3342
https://doi.org/10.1158/0008-5472.can-10-3342
Autor:
Chung Wah Wu, Ming-Wei Wang, Linwei Tian, Ming-Liang He, Kin-Fai Cheung, William K.K. Wu, Xiaoxing Li, Xiaowei Ma, Jun Yu, Simon S.M. Ng, Shanshan Wang, Joseph J.Y. Sung
Publikováno v:
Oncogene. 29:6464-6474
T-box transcription factor 5 (TBX5) is a member of a phylogenetically conserved family of genes involved in the regulation of developmental processes. The function of TBX5 in cancer development is largely unclear. We identified that TBX5 was preferen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9531de63f2933372ccbfb34dad3c94b9
https://doi.org/10.1038/onc.2010.370
https://doi.org/10.1038/onc.2010.370
Autor:
Linwei Tian, Qian Tao, Kin-Fai Cheung, Simon S.M. Ng, Jun Yu, Yuen Yee Cheng, K.F. Lee, Matthias P.A. Ebert, Francis K.L. Chan, Sunyoung Rha, Ulf Neumann, Christoph Röcken, Joseph J.Y. Sung
Publikováno v:
Cancer. 115:49-60
BACKGROUND: Abnormal activation of the Wnt/β-catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene Dkk-3 in these ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05f4041497535736da9a9cc09a3dd0c4
https://doi.org/10.1002/cncr.23989
https://doi.org/10.1002/cncr.23989
Autor:
Sing Fai Leung, Philip Wai Yan Chiu, Angus C.W. Chan, Simon Kin Hung Wong, James F. Griffith, Alex C.M. Au-Yeung, Sydney S.C. Chung, Kin-Fai Cheung, Enders K.W. Ng
Publikováno v:
Annals of Surgical Oncology. 15:576-582
We evaluated the role of chemoradiotherapy (CRT) for patients with inoperable squamous esophageal cancer.Patients with locally advanced or metastatic squamous esophageal carcinoma who received CRT were recruited. The CRT consists of continuous infusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c574e11a035792100c79006a7a075ea
https://doi.org/10.1245/s10434-007-9679-y
https://doi.org/10.1245/s10434-007-9679-y