Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Kin Fai Chan"'
Autor:
Kathy Hiu Laam Po, Hoi Yee Chow, Qipeng Cheng, Bill Kwan‐wai Chan, Xin Deng, Shuping Wang, Edward Wai Chi Chan, Hang‐Kin Kong, Kin Fai Chan, Xuechen Li, Sheng Chen
Publikováno v:
Natural Sciences, Vol 1, Iss 2, Pp n/a-n/a (2021)
Abstract Daptomycin, as a lipopeptide antibiotic, exhibits high potency in the treatment of infections caused by clinically relevant drug‐resistant Gram‐positive pathogens, such as methicillin‐resistant Staphylococcus aureus and vancomycin‐re
Externí odkaz:
https://doaj.org/article/a6bad123c9a94b91940a8c8acc3bb816
Autor:
Wenbin Jin, Chen Xu, Ning Dong, Kaichao Chen, Die Zhang, Jinhua Ning, Yunbing Li, Guangfen Zhang, Jin Ke, Anguo Hou, Linyun Chen, Sheng Chen, Kin-Fai Chan
Publikováno v:
BMC Chemistry, Vol 17, Iss 1, Pp 1-13 (2023)
Abstract Carbapenem-resistant Enterobacterales (CRE) has emerged as a worldwide spread nosocomial superbug exhibiting antimicrobial resistance (AMR) to all current antibiotics, leaving limited options for treating its infection. To discovery novel an
Externí odkaz:
https://doaj.org/article/b64a1ec6123c4f7083e0a713cf808327
Autor:
Kin-Fai Chan, Ning Sun, Siu-Cheong Yan, Iris L. K. Wong, Hok-Kiu Lui, Kwan-Choi Cheung, Jian Yuan, Fung-Yi Chan, Zhiwei Zheng, Edward W. C. Chan, Sheng Chen, Yun-Chung Leung, Tak Hang Chan, Kwok-Yin Wong
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 7281-7292 (2017)
Externí odkaz:
https://doaj.org/article/fe43b9ffa0e742c497654357194e1226
Autor:
Larry M.C. Chow, Chin-Fung Chan, Man Chun Law, Xuezhen Zhu, Tsz Cheung Chong, Zhen Liu, Tsun Sing Chow, Jiahua Cui, Kin-Fai Chan, Tak Hang Chan, Iris L. K. Wong
Publikováno v:
Journal of Medicinal Chemistry. 64:14311-14331
We synthesize various substituted triazole-containing flavonoids and identify potent, nontoxic, and highly selective BCRP inhibitors. Ac18Az8, Ac32Az19, and Ac36Az9 possess m-methoxycarbonylbenzyloxy substitution at C-3 of the flavone moiety and subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e263f6d662e83c7fb1095f6382fe523f
https://doi.org/10.1021/acs.jmedchem.1c00779
https://doi.org/10.1021/acs.jmedchem.1c00779
Autor:
Ping Zeng, Pengfei Zhang, Lanhua Yi, Kwok-Yin Wong, Sheng Chen, Kin-Fai Chan, Sharon Shui Yee Leung
Publikováno v:
Food Chemistry. 413:135647
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecbd334c5616afc68c2afbaf8dac85ee
https://doi.org/10.1016/j.foodchem.2023.135647
https://doi.org/10.1016/j.foodchem.2023.135647
Publikováno v:
ACS Food Science & Technology. 1:614-624
Pectobacterium carotovorum is a Gram-negative plant-specific pathogen that causes severe rot of postharvest vegetables. Given the safety consideration of pesticides, we developed a peptide approach...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::395d99ac5e8f72c344a42b72695cac73
https://doi.org/10.1021/acsfoodscitech.1c00037
https://doi.org/10.1021/acsfoodscitech.1c00037
Autor:
Chen Xu, Yun Chung Leung, Sheng Chen, Wen Bin Jin, Tak Hang Chan, Edward Wai-Chi Chan, Wei Gao, Kin-Fai Chan, Ki Hon Lai, Ping Zeng, Kwok Yin Wong, Jiachi Chiou, Xiao Lin Qi
Publikováno v:
New Journal of Chemistry. 45:3515-3534
The effective strategies to neutralize the New Delhi metallo-β-lactamase (NDM-1) activity offer unique opportunities to combination therapy because NDM-1 inactivates all classes of carbapenem antibiotics, which are widely regarded as the last resort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::157dc763ea07962677f4db794995f56b
https://doi.org/10.1039/d0nj06090a
https://doi.org/10.1039/d0nj06090a
Autor:
Jun Liu, Xuemei Yang, Chenyu Liu, Chen Xu, Sheng Chen, Wei Gao, Qipeng Cheng, Kin-Fai Chan, Ping Zeng, Kwok Yin Wong
Publikováno v:
ACS Applied Bio Materials. 3:1738-1752
Given the worldwide prevalence of pathogenic drug-resistant bacteria and the slow pace of new antibacterial development, discovering new uses for approved drugs that are outside the scope of the or...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e35f6fe26e6dbfcb36221285566c8d2e
https://doi.org/10.1021/acsabm.0c00044
https://doi.org/10.1021/acsabm.0c00044
C-terminal modification of a de novo designed antimicrobial peptide via capping of macrolactam rings
Autor:
Ping Zeng, Qipeng Cheng, Lanhua Yi, Sharon Shui Yee Leung, Sheng Chen, Kin-Fai Chan, Kwok-Yin Wong
Publikováno v:
Bioorganic Chemistry. 130:106251
In this work, by capping a macrolactam ring at the C-terminus of a de novo-designed peptide, namely zp80, we have constructed a small peptide library via the solid phase peptide synthesis for screening. Eight peptides bearing different aspartic acid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ce9222983197e5a8157efd60d7a804
https://doi.org/10.1016/j.bioorg.2022.106251
https://doi.org/10.1016/j.bioorg.2022.106251
Autor:
Hang-kin Kong, Hoi Yee Chow, Xuechen Li, Kathy Hiu Laam Po, Shuping Wang, Bill Kwan-wai Chan, Qipeng Cheng, Kin-Fai Chan, Edward Chan, Sheng Chen, Xin Deng
Publikováno v:
Natural Sciences, Vol 1, Iss 2, Pp n/a-n/a (2021)
Daptomycin, as a lipopeptide antibiotic, exhibits high potency in the treatment of infections caused by clinically relevant drug‐resistant Gram‐positive pathogens, such as methicillin‐resistant Staphylococcus aureus and vancomycin‐resistant E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ba44f881eceb69cac8e369a6ba4f3d
https://doi.org/10.1002/ntls.10023
https://doi.org/10.1002/ntls.10023