Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kin Chun Luk"'
Autor:
Eileen A. Friedman, John F. Boylan, Karen Zipf, Ann F. Hoffman, Ann Polonskaia, Kin-chun Luk, Xiaobing Deng, Maria Vilenchik, Jing Hu, Daina Z. Ewton
PDF file - 57K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328d46e1571d98bc8451fe866053f6ca
https://doi.org/10.1158/1535-7163.22496568
https://doi.org/10.1158/1535-7163.22496568
Autor:
Eileen A. Friedman, John F. Boylan, Karen Zipf, Ann F. Hoffman, Ann Polonskaia, Kin-chun Luk, Xiaobing Deng, Maria Vilenchik, Jing Hu, Daina Z. Ewton
PDF file - 286K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ac18212c658b7ba08ee3ed2fb35a40
https://doi.org/10.1158/1535-7163.22496574.v1
https://doi.org/10.1158/1535-7163.22496574.v1
Autor:
Eileen A. Friedman, John F. Boylan, Karen Zipf, Ann F. Hoffman, Ann Polonskaia, Kin-chun Luk, Xiaobing Deng, Maria Vilenchik, Jing Hu, Daina Z. Ewton
PDF file - 488K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccfe697436a195197ab6139e1da301d
https://doi.org/10.1158/1535-7163.22496577.v1
https://doi.org/10.1158/1535-7163.22496577.v1
Autor:
Eileen A. Friedman, John F. Boylan, Karen Zipf, Ann F. Hoffman, Ann Polonskaia, Kin-chun Luk, Xiaobing Deng, Maria Vilenchik, Jing Hu, Daina Z. Ewton
PDF file - 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49300c2d238b53eef6a5b1e77e7ca1c9
https://doi.org/10.1158/1535-7163.22496571
https://doi.org/10.1158/1535-7163.22496571
Autor:
Eileen A. Friedman, John F. Boylan, Karen Zipf, Ann F. Hoffman, Ann Polonskaia, Kin-chun Luk, Xiaobing Deng, Maria Vilenchik, Jing Hu, Daina Z. Ewton
A major problem in the treatment of cancer arises from quiescent cancer cells that are relatively insensitive to most chemotherapeutic drugs and radiation. Such residual cancer cells can cause tumor regrowth or recurrence when they reenter the cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::982e1d19b9983053d3ae3dde4af007fa
https://doi.org/10.1158/1535-7163.c.6535326
https://doi.org/10.1158/1535-7163.c.6535326
Autor:
Eileen A. Friedman, John F. Boylan, Karen Zipf, Ann F. Hoffman, Ann Polonskaia, Kin-chun Luk, Xiaobing Deng, Maria Vilenchik, Jing Hu, Daina Z. Ewton
PDF file - 387K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbb0d061e4df7d708f5b2bc6cb7f280
https://doi.org/10.1158/1535-7163.22496586.v1
https://doi.org/10.1158/1535-7163.22496586.v1
Autor:
Jin-Jun Liu, Cheryl Janson, Jing Zhang, Brian Higgins, David Joseph Bartkovitz, Zoran Filipovic, Kin-Chun Luk, Christian Tovar, Qingjie Ding, Bradford Graves, Zhuming Zhang, Lyubomir T. Vassilev, Kelli Glenn, Xin-Jie Chu, Packman Kathryn E, Nan Jiang
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:4001-4009
The field of small-molecule inhibitors of protein–protein interactions is rapidly advancing and the specific area of inhibitors of the p53/MDM2 interaction is a prime example. Several groups have published on this topic and multiple compounds are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc77838bb75adf351828dfa55c8c791
https://doi.org/10.1016/j.bmc.2014.05.072
https://doi.org/10.1016/j.bmc.2014.05.072
Autor:
Peter Michael Wovkulich, Cheryl Janson, Hongmao Sun, Yang He, Rossman Pamela Loreen, Qing Xiang, Xiaolei Zhang, Zhi Chen, Qi Qiao, Romyr Dominique, Christine Lukacs, Kin-Chun Luk, Yi Chen, Kevin W. Anderson, Aruna Railkar, Kelli Glenn, Ann Polonskaia, Masha Vilenchik
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:6610-6615
DYRK1B is a kinase over-expressed in certain cancer cells (including colon, ovarian, pancreatic, etc.). Recent publications have demonstrated inhibition of DYRK1B could be an attractive target for cancer therapy. From a data-mining effort, the team h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc5019acedd92e1f83d6b4a4d17562a
https://doi.org/10.1016/j.bmcl.2013.10.055
https://doi.org/10.1016/j.bmcl.2013.10.055
Autor:
Jing Hu, Ann F. Hoffman, Xiaobing Deng, Karen Zipf, Maria Vilenchik, Ann Polonskaia, Daina Z. Ewton, Eileen Friedman, John Frederick Boylan, Kin-Chun Luk
Publikováno v:
Molecular Cancer Therapeutics. 10:2104-2114
A major problem in the treatment of cancer arises from quiescent cancer cells that are relatively insensitive to most chemotherapeutic drugs and radiation. Such residual cancer cells can cause tumor regrowth or recurrence when they reenter the cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c965b4e89680a7f204ddda7f37e26a5f
https://doi.org/10.1158/1535-7163.mct-11-0498
https://doi.org/10.1158/1535-7163.mct-11-0498
Autor:
Zhuming Zhang, Melissa Smith, Navita L. Mallalieu, Omar Jose Morales, Kin-Chun Luk, Lee Apostle Mcdermott, Jia K. Li, Tom Flynn, Yi Chen, Brian Higgins, June Ke, Jin-Jun Liu, Hong Yang, Fred Konzelmann, Mary Simcox, Tom Nevins, Thomas Egan, Yingsi Chen, Kenneth Kolinsky, Louise Gerber, Aruna Railkar, Stan Kolis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:1950-1953
RO4396686 is a small molecule KDR, FGFR, and PDGFR inhibitor with good pharmacokinetic properties in rodents. In a mouse corneal neovascularization assay, this compound inhibited VEGF-induced angiogenesis. Tested in a H460a xenograft tumor model this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9e17ce43056e160291c9e5b5ce543e
https://doi.org/10.1016/j.bmcl.2005.12.092
https://doi.org/10.1016/j.bmcl.2005.12.092