Výsledky vyhledávání - "Kin Choo Pua"

Akademický článek

In vitro evaluation of dual-antigenic PV1 peptide vaccine in head and neck cancer patients

Autor: San Jiun Chai, Sammuel Chee Yong Fong, Chai Phei Gan, Kin Choo Pua, Paul Vey Hong Lim, Shin Hin Lau, Rosnah Binti Zain, Thomas Abraham, Siti Mazlipah Ismail, Zainal Ariff Abdul Rahman, Sathibalan Ponniah, Vyomesh Patel, Sok Ching Cheong, Kue Peng Lim

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 15, Iss 1, Pp 167-178 (2019)

Peptide vaccines derived from tumour-associated antigens have been used as an immunotherapeutic approach to induce specific cytotoxic immune response against tumour. We previously identified that MAGED4B and FJX1 proteins are overexpressed in HNSCC p

Externí odkaz: https://doaj.org/article/ba11ad8f5d45434c845f6d791e87ae5c

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Akademický článek

A Genome Wide Study of Copy Number Variation Associated with Nasopharyngeal Carcinoma in Malaysian Chinese Identifies CNVs at 11q14.3 and 6p21.3 as Candidate Loci.

Autor: Joyce Siew Yong Low, Yoon Ming Chin, Taisei Mushiroda, Michiaki Kubo, Gopala Krishnan Govindasamy, Kin Choo Pua, Yoke Yeow Yap, Lee Fah Yap, Selva Kumar Subramaniam, Cheng Ai Ong, Tee Yong Tan, Alan Soo Beng Khoo, Malaysian NPC Study Group, Ching Ching Ng

Publikováno v: PLoS ONE, Vol 11, Iss 1, p e0145774 (2016)

BACKGROUND:Nasopharyngeal carcinoma (NPC) is a neoplasm of the epithelial lining of the nasopharynx. Despite various reports linking genomic variants to NPC predisposition, very few reports were done on copy number variations (CNV). CNV is an inheren

Externí odkaz: https://doaj.org/article/8e7fa5cd0c6740c49c419f65ce18740c

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Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort

Autor: Yusuke Nakamura, Lu Ping Tan, Yoke-Yeow Yap, Noor Kaslina Mohd Kornain, Alan Soo-Beng Khoo, Taisei Mushiroda, Ching Ching Ng, Chee Lun Lum, Yoon-Ming Chin, Norazlin Abdul Aziz, Kin-Choo Pua, Geok Wee Tan, Soo-Hwang Teo, Paul Vey Hong Lim, Gopala Krishnan, Michiaki Kubo

Publikováno v: International Journal of Cancer. 139:1731-1739

Nasopharyngeal carcinoma (NPC) is an epithelial squamous cell carcinoma on the mucosal lining of the nasopharynx. The etiology of NPC remains elusive despite many reported studies. Most studies employ a single platform approach, neglecting the cumula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fffc671fe66abb2576ee03a3956d2fb4
https://doi.org/10.1002/ijc.30207

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Clinico-pathological features of oropharyngeal squamous cell carcinomas in Malaysia with reference to HPV infection

Autor: Anthony Rhodes, Phaik-Leng Cheah, Selvam Thavaraj, Lee Fah Yap, Pathmanathan Rajadurai, Max Robinson, Kin Choo Pua, Sook Ling Lai, Ian C. Paterson, Hans Prakash Sathasivam, Maizaton Atmadini Abdullah

Publikováno v: Infectious Agents and Cancer
Infectious Agents and Cancer, Vol 13, Iss 1, Pp 1-6 (2018)

Background The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising in Western countries and this has been attributed to human papillomavirus (HPV) infection. p16 expression is a marker for HPV infection and p16 positive OPSCC i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65b58719698eed980cc0305c9f7030e
https://doi.org/10.1186/s13027-018-0193-6

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Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma

Autor: Rajadurai Pathmanathan, Noor Kaslina Mohd Kornain, Lu Ping Tan, Kin Choo Pua, Chee Lun Lum, Alan Soo Beng Khoo, San Jiun Chai, Vyomesh Patel, Siew Woh Choo, Yoke Yeow Yap, Paul Vey Hong Lim, Tee Yong Tan, Norazlin Abdul Aziz, Yock Ping Chow, Soo-Hwang Teo

Publikováno v: Scientific Reports

In this study, we first performed whole exome sequencing of DNA from 10 untreated and clinically annotated fresh frozen nasopharyngeal carcinoma (NPC) biopsies and matched bloods to identify somatically mutated genes that may be amenable to targeted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3153068ff0f244c50784b80079629df9
https://pubmed.ncbi.nlm.nih.gov/28256603

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Clinical significance of plasma Epstein–Barr Virus DNA loads in a large cohort of Malaysian patients with nasopharyngeal carcinoma

Autor: Wan Rozita Wan Mahiyuddin, Yoke Yeow Yap, Selva Kumar Subramaniam, Alan S.B. Khoo, Soo-Hwang Teo, Kin Choo Pua, Lee Fah Yap, Chee Lun Lum, Gopala Krishnan, Amyza Saleh, Paul Vey Hong Lim, San Jiun Chai

Publikováno v: Journal of Clinical Virology. 55:34-39

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr Virus (EBV)-associated cancer that is the fifth most common cancer in Malaysia. Early and accurate diagnoses are critical for patient prognosis. Unfortunately, early detection of NPC is still a challe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac3482b7532cd9f42b966c912a75121
https://doi.org/10.1016/j.jcv.2012.05.017

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Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort

Autor: Yoon-Ming, Chin, Lu Ping, Tan, Norazlin, Abdul Aziz, Taisei, Mushiroda, Michiaki, Kubo, Noor Kaslina, Mohd Kornain, Geok Wee, Tan, Alan Soo-Beng, Khoo, Gopala, Krishnan, Kin-Choo, Pua, Yoke-Yeow, Yap, Soo-Hwang, Teo, Paul Vey-Hong, Lim, Yusuke, Nakamura, Chee Lun, Lum, Ching-Ching, Ng

Publikováno v: International journal of cancer. 139(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75532e2e2303704237f6742988f09d7d
https://pubmed.ncbi.nlm.nih.gov/27236004

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