Combined role for YAP-TEAD and YAP-RUNX2 signalling in substrate-stiffness regulation of cardiac fibroblast proliferation

Autor: Ebrahimighaei, Reza, Sala-Newby, Graciela B., Hudson, Claire, Kimura, Tomomi E., Hathway, Tom, Hawkins, Joseph, McNeill, Madeleine C., Richardson, Rebecca, Newby, Andrew C., Bond, Mark ^⁎

Publikováno v: In BBA - Molecular Cell Research November 2022 1869(11)

cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1

Autor: Duggirala, Aparna ^a, Kimura, Tomomi E. ^a, Sala-Newby, Graciela B. ^a, Johnson, Jason L. ^a, Wu, Yih-Jer ^{b, c}, Newby, Andrew C. ^a, Bond, Mark ^{a, ⁎}

Publikováno v: In Journal of Molecular and Cellular Cardiology February 2015 79:157-168

Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes

Autor: Bryant, Simon, Kimura, Tomomi E., Kong, Cherrie H.T., Watson, Judy J., Chase, Anabelle, Suleiman, M. Saadeh, James, Andrew F. ^⁎, Orchard, Clive H. ^⁎

Publikováno v: In Journal of Molecular and Cellular Cardiology March 2014 68:47-55

Mitogen-activated Protein Kinase Kinase 4 Deficiency in Cardiomyocytes Causes Connexin 43 Reduction and Couples Hypertrophic Signals to Ventricular Arrhythmogenesis

Autor: Zi, Min ^{‡, 1}, Kimura, Tomomi E. ^{§, 1}, Liu, Wei ^§, Jin, Jiawei ^§, Higham, Jonathan ^¶, Kharche, Sanjay ^¶, Hao, Guoliang ^‡, Shi, Ying ^‡, Shen, Weijian ^¶, Prehar, Sukhpal ^‡, Mironov, Aleksandr ^§, Neyses, Ludwig ^‡, Bierhuizen, Marti F.A. ^‖, Boyett, Mark R. ^‡, Zhang, Henggui ^¶, Lei, Ming ^‡, Cartwright, Elizabeth J. ^‡, Wang, Xin ^{§, 2}

Publikováno v: In Journal of Biological Chemistry 20 May 2011 286(20):17821-17830

Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function

Autor: Hudson, Claire, Kimura, Tomomi E., Duggirala, Aparna, Sala-Newby, Graciela B., Newby, Andrew C., Bond, Mark

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Hudson, C, Kimura, T E, Duggirala, A, Sala-Newby, G B, Newby, A C & Bond, M 2018, ' Dual role of CREB in the regulation of VSMC proliferation : mode of activation determines pro-or anti-mitogenic function ', Scientific Reports, vol. 8, 4904 . https://doi.org/10.1038/s41598-018-23199-4

Vascular smooth muscle cell (VSMC) proliferation has been implicated in the development of restenosis after angioplasty, vein graft intimal thickening and atherogenesis. We investigated the mechanisms underlying positive and negative regulation of VS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a50ed4758c6881b7b478347a14346fb6
http://link.springer.com/article/10.1038/s41598-018-23199-4