The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth.

Autor: Bowers LW; Department of Nutrition, University of North Carolina, 135 Dauer Drive, CB #7461, Chapel Hill, NC, 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, 450 West Drive, Chapel Hill, NC, 27514, USA., Lineberger CG; Department of Nutrition, University of North Carolina, 135 Dauer Drive, CB #7461, Chapel Hill, NC, 27599, USA., Ford NA; Department of Nutritional Sciences, University of Texas at Austin, 1400 Barbara Jordan Blvd, R1800, Austin, TX, 78723, USA., Rossi EL; Department of Nutrition, University of North Carolina, 135 Dauer Drive, CB #7461, Chapel Hill, NC, 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, 450 West Drive, Chapel Hill, NC, 27514, USA., Punjala A; Department of Nutrition, University of North Carolina, 135 Dauer Drive, CB #7461, Chapel Hill, NC, 27599, USA., Camp KK; Department of Nutrition, University of North Carolina, 135 Dauer Drive, CB #7461, Chapel Hill, NC, 27599, USA., Kimler BK; Department of Radiation Oncology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA., Fabian CJ; Department of Internal Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA., Hursting SD; Department of Nutrition, University of North Carolina, 135 Dauer Drive, CB #7461, Chapel Hill, NC, 27599, USA. hursting@email.unc.edu.; Lineberger Comprehensive Cancer Center, University of North Carolina, 450 West Drive, Chapel Hill, NC, 27514, USA. hursting@email.unc.edu.; Nutrition Research Institute, University of North Carolina, 500 Laureate Way, Kannapolis, NC, 28081, USA. hursting@email.unc.edu.

Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2019 Feb; Vol. 173 (3), pp. 545-557. Date of Electronic Publication: 2018 Oct 26.