Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kimio Kawano"'
Autor:
Hiroyuki Hoshino, Kimio Kawano, Toru Okuda, Maki Nishio, Noboru Kishi, Tetsuo Ohnuki, Masaaki Sakurai, Jun Kohno
Publikováno v:
The Journal of Antibiotics. 56:787-791
Publikováno v:
The Journal of Antibiotics. 56:513-519
A novel inhibitor of STAT6 activation, named as TMC-264 (1), was discovered from the fermentation broth of Phoma sp. TC 1674. Based on spectroscopic analyses, TMC-264 was found to be a novel tricyclic polyketide with chloro-1H-dibenzo[b,d]pyran-4,6-d
Autor:
Kimio Kawano, Saburo Komatsubara, Toru Okuda, Noriyuki Nakanishi, Shiho Tsunoda, Naomitsu Hirano, Maki Nishio, Noboru Kishi, Jun Kohno
Publikováno v:
The Journal of Antibiotics. 54:421-427
A new antibiotic designated TMC-69 has been isolated from, the fermentation broth of a fungal strain Chrysosporium sp. TC 1068. TMC-69 exhibited moderate in vitro cytotoxic activity. TMC-69-6H, a derivative of TMC-69 prepared by hydrogenation, posses
Autor:
Toru Okuda, Kozo Yamamoto, Noriyuki Nakanishi, Jun Kohno, Kimio Kawano, Maki Nishio, Masaaki Sakurai
Publikováno v:
The Journal of Antibiotics. 54:628-634
A new transcriptional up-regulator designated TMC-205 was discovered from the fermentation broth of an unidentified fungal strain TC 1630 by using an SV40 promoter-luciferase reporter assay. Based on spectroscopic analyses, its structure was determin
Autor:
Maki Nishio, Masaaki Sakurai, Saburo Komatsubara, Kimio Kawano, Toyoharu Yamashita, Noboru Kishi, Noriaki Kameda, Hajime Hiramatsu, Jun Kohno, Toru Okuda
Publikováno v:
Tetrahedron. 55:7771-7786
Six new antibiotics, TMC-151 A-F (2–7) have been isolated from organic extracts of the fermentation broth of Gliocladium catenulatum Gilman & Abbott TC 1280, isolated from a soil sample. Their structures including the absolute stereochemistries, we
Autor:
Hajime Hiramatsu, Toru Okuda, Maki Nishio, Masaaki Sakurai, Yasuyuki Asai, Kimio Kawano, Noriaki Kameda, Saburo Komatsubara, Jun Kohno, Noboru Kishi
Publikováno v:
The Journal of Antibiotics. 52:1114-1123
Four new antibiotics, TMC-171A (2), B (3), C (4) and TMC-154 (5) have been isolated from the fermentation of fungal strains Gliocladium sp. TC 1304 and TC 1282, respectively. Spectroscopic and degradation studies have shown that TMC-171s and TMC-154
Autor:
Kimio Kawano, Maki Nishio, Saburo Komatsubara, Noriyuki Nakanishi, Jun Kohno, Tomofumi Uchida, Shin-Ichi Suzuki
Publikováno v:
The Journal of Antibiotics. 49:1212-1220
Four new antitumor antibiotics, TMC-1 A, B, C and D were isolated from a fermentation broth of Streptomyces sp. A-230. Spectroscopic studies have shown that TMC-1 A to D were new members of the manumycin class of antibiotics. These antibiotics showed
Publikováno v:
Organic Letters. 5:1083-1085
[structure: see text] TMC-264 (1), a novel tricyclic heptaketide with a unique chloro-1H-dibenzo[b,d]pyran-4,6-dione skeleton, was discovered from the fungus Phoma sp. TC 1674. The structure was elucidated on the basis of NMR analyses of normal abund
Autor:
Noriyuki Ohkusa, Toshikazu Oki, Kimio Kawano, Yosuke Sawada, Shiu-Lok Hu, Seiji Iimura, Yasuo Fukagawa, Masaru Sugawara, Haruaki Yamamoto, Masahisa Oka, Osamu Tenmyo
Publikováno v:
The Journal of Antibiotics. 46:367-373
Terpestacin, a new antibiotic which inhibits syncytium formation, was isolated from Arthrinium sp. FA1744 (ATCC 74132). The structure of terpestacin was elucidated as a bicyclic sesterterpene on the basis of spectroscopic data and chemical derivatiza
Publikováno v:
ChemInform. 27