Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Kiminao MIZUKAWA"'
Publikováno v:
Neuroscience Research. 30:43-52
To investigate dopamine (DA) levels as well as DA metabolism by which the striatal DAergic grafts may bring the functional recovery to hemiparkinsonian model rats, a microdialysis study was performed in the striatum, and an autoradiographic analysis
Publikováno v:
International Journal of Stress Management. 1:299-307
It is known that nitroglycerin (GTN) can be converted to form a nitric oxide (NO) molecule which is a highly reactive and unstable free radical species. NO is known to have many beneficial effects such as relaxing blood vessels, promoting digestive a
Autor:
Hiromi Iwagaki, Kunzo Orita, Nagahide Matsubara, Yasuhiro Kimura, Sadanori Fuchimoto, Kiminao Mizukawa
Publikováno v:
Pathophysiology. 1:47-51
Recently we demonstrated that constitutive production of hydroxyl radicals could be shown by measuring the radical spin adducts using a spin trap and electron paramagnetic resonance spectrometer. Using this method, we show that various cancer cell li
Autor:
Kiminao Mizukawa, Sakiko Nishibayashi, Ken-ichi Tanaka, Akitane Mori, Norio Ogawa, Yoichi Kondo, Masato Asanuma
Publikováno v:
Neurochemical Research. 19:117-122
The effects of pre-treatment with ENA-713, an acetylcholinesterase (AChE) inhibitor, on changes in pre- and postsynaptic cholinergic indices in gerbil brain following transient ischemia were studied at 4 and 14 days after recirculation. In the ischem
Autor:
Junzo Ochi, Kazuwa Nakao, Masahiko Kinoshita, Kiminao Mizukawa, Tamaki Nishimura, Hisao Yamada
Publikováno v:
Archives of Histology and Cytology. 57:1-7
The distribution of atrial natriuretic polypeptide (ANP) and atrial specific granules in the myocytes of the atria and ventricles of an experimental animal model, stroke-prone spontaneously hypertensive rats (SHRSP) and a control, Wistar Kyoto rats (
Publikováno v:
Archives of Gerontology and Geriatrics. 17:77-89
Receptor binding assays and in vitro macroautoradiography were used to analyze muscarinic cholinergic receptors (MCR) in the cerebral frontal cortex of Alzheimer's disease (AD), senile dementia of Alzheimer type (SDAT), and age-matched control brains
Publikováno v:
Neuroscience Research. 17:23-30
We produced an improved microembolism model of cerebral focal ischemia by injection of 1000–2000 microspheres (50 ± 5 μ m diameter) via a tube retrogradely inserted into the right external carotid artery in freely moving rats. The group injected
Publikováno v:
Neuroscience Letters. 152:173-176
We previously reported that a late onset reduction of muscarinic acetylcholine receptors (LORMAR) occurs in the gerbil hippocampus after 5 min of transient ischemia. This reduction begins as late as 7 days post-ischemia and accompanies the accumulati
Publikováno v:
Neurochemical Research. 17:687-691
We assayed N-methyl-D-aspartate (NMDA) receptors [3H]3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid ([3H]CPP) bindings) and evaluated their distribution in the brain by quantitative autoradiography in young adult and aged rats. In the young adul
Publikováno v:
Developmental Brain Research. 65:119-122
We have previously found that neonatal administration of cytosine arabinoside (Ara-C) induces cerebellar malformation, including arrest of granule cell migration and destruction of glial palisade. In the present study, the expression of neural cell a