Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kimiko M, Tsutsui"'
Autor:
Rifat Ara Najnin, Md Rasel Al Mahmud, Md Maminur Rahman, Shunichi Takeda, Hiroyuki Sasanuma, Hisashi Tanaka, Yasuhiro Murakawa, Naoto Shimizu, Salma Akter, Masatoshi Takagi, Takuro Sunada, Shusuke Akamatsu, Gang He, Junji Itou, Masakazu Toi, Mary Miyaji, Kimiko M. Tsutsui, Scott Keeney, Shintaro Yamada
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111909- (2023)
Summary: ATM gene mutation carriers are predisposed to estrogen-receptor-positive breast cancer (BC). ATM prevents BC oncogenesis by activating p53 in every cell; however, much remains unknown about tissue-specific oncogenesis after ATM loss. Here, w
Externí odkaz:
https://doaj.org/article/fc73a448f05d4c34af1641771aac7840
Autor:
Mary Miyaji, Ryohei Furuta, Osamu Hosoya, Kuniaki Sano, Norikazu Hara, Ryozo Kuwano, Jiyoung Kang, Masaru Tateno, Kimiko M. Tsutsui, Ken Tsutsui
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Type II DNA topoisomerases (topo II) flip the spatial positions of two DNA duplexes, called G- and T- segments, by a cleavage-passage-resealing mechanism. In living cells, these DNA segments can be derived from distant sites on the same chro
Externí odkaz:
https://doaj.org/article/5291d081cd5a40e69f1221a370ac306d
Autor:
Kyoko Nakamura, Toshiaki Kogame, Hiroyuki Oshiumi, Akira Shinohara, Yoshiki Sumitomo, Keli Agama, Yves Pommier, Kimiko M Tsutsui, Ken Tsutsui, Edgar Hartsuiker, Tomoo Ogi, Shunichi Takeda, Yoshihito Taniguchi
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000828 (2010)
Topoisomerase inhibitors such as camptothecin and etoposide are used as anti-cancer drugs and induce double-strand breaks (DSBs) in genomic DNA in cycling cells. These DSBs are often covalently bound with polypeptides at the 3' and 5' ends. Such modi
Externí odkaz:
https://doaj.org/article/7b2bc382af5b4b5b85a20ce23adb65aa
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e4103 (2008)
DNA topoisomerase II (topo II) catalyzes a strand passage reaction in that one duplex is passed through a transient brake or gate in another. Completion of late stages of neuronal development depends on the presence of active beta isoform (topo IIbet
Externí odkaz:
https://doaj.org/article/5c381ccd7f13485b915931276dfe8ce3
Publikováno v:
Acta Medica Okayama. 59(4):113-120
The nuclear matrix is an operationally defined nuclear skeletal structure that is believed to be involved in many nuclear functions including DNA replication, transcription, repair, and prem RNA processing/transport. Until relatively recently, the nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4bddc177876666acb17e8a93f928bd62
https://ousar.lib.okayama-u.ac.jp/31953
https://ousar.lib.okayama-u.ac.jp/31953
Publikováno v:
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de3cd661299dce8390ff91894230923b
https://pubmed.ncbi.nlm.nih.gov/19764468
https://pubmed.ncbi.nlm.nih.gov/19764468
Publikováno v:
The Journal of biological chemistry. 276(8)
Two isoforms of DNA topoisomerase II (topo II) have been identified in mammalian cells. While topo IIalpha is essential for chromosome segregation in mitotic cells, in vivo function of topo IIbeta remains to be clarified. Here we demonstrate that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903269d7775d795b3351dc3bd1b65e84
https://pubmed.ncbi.nlm.nih.gov/11106659
https://pubmed.ncbi.nlm.nih.gov/11106659