Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Kimiko Kobayashi"'
Autor:
Masamichi Okubo, Hiroki Yamanaka, Kimiko Kobayashi, Yi Dai, Hirosato Kanda, Hideshi Yagi, Koichi Noguchi
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153375 (2016)
Peripheral nerve injury induces proliferation of microglia in the spinal cord, which can contribute to neuropathic pain conditions. However, candidate molecules for proliferation of spinal microglia after injury in rats remain unclear. We focused on
Externí odkaz:
https://doaj.org/article/b4ed70f658b44416abcd3f8127f03854
Autor:
Ryo Kawabata, Hiroki Yamanaka, Kimiko Kobayashi, Yoshihiko Oke, Ayumi Fujita, Yoshitaka Oku, Ikuko Yao, Kohei Koga
Publikováno v:
Neuroscience.
Autor:
Hirosato Kanda, Shaoqi Duan, Hiroki Yamanaka, Koichi Noguchi, Masashi Fukushima, Hiroto Miwa, Tadahiro Fujimura, Takashi Kondo, Hiroki Okada, Yi Dai, Yoshihito Fujii, Toshihiko Tomita, Tadayuki Oshima, Hirokazu Fukui, Takashi Konemura, Tomoaki Kono, Kimiko Kobayashi
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 70:28-32
Publikováno v:
PAIN RESEARCH. 36:147-153
Publikováno v:
Molecular pain. 18
Itch and pain are both unpleasant, but they are discrete sensations. Both of these sensations are transmitted by C-fibers and processed in laminae I-II of the dorsal horn. To examine whether pruriception modulates pain, we first confirmed the activat
Publikováno v:
The Journal of Physiology. 599:1783-1798
KEY POINTS Nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) are essential for neuronal development and survival in embryo. However, after birth they play pivotal roles in the generation of hyperalgesia in many painful
Autor:
Hiroki Yamanaka, Kazuya Kishima, Keishi Maruo, Masamichi Okubo, Koichi Noguchi, Toshiya Tachibana, Kimiko Kobayashi
Publikováno v:
The Spine Journal. 21:343-351
Spinal cord injury (SCI) can lead to increased phosphorylation of p38 in spinal cord microglia. This is one of the main causes for the development of persistent pain. Recently, we reported our study on the activation of p38 mitogen-activated protein
Publikováno v:
The Journal of physiologyReferences. 599(17)
Publikováno v:
eNeuro
In the dorsal horn of the spinal cord, peripheral nerve injury induces structural and neurochemical alterations through which aberrant synaptic signals contribute to the formation of neuropathic pain. However, the role of injured primary afferent ter
Autor:
Naomi Hirakawa, Hiromitsu Hara, Toshiharu Yasaka, Yuzo Murata, Tomoko Sasaguri, Ei’ichi Iizasa, Kimiko Kobayashi, Makoto Tsuda, Sayaka Iizasa, Toru Taguchi, Hiroki Yoshida
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Numerous studies have shown that pain sensation is affected by various immune molecules, such as cytokines, in tissues comprising the sensory pathway. Specifically, it has been shown that interleukin (IL)-17 promotes pain behaviour, but IL-10 suppres