Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kimihisa Yoshida"'
Publikováno v:
Proceedings of the National Academy of Sciences. 108:16571-16576
So far, only a few of the interactions between the ≈30 nucleoporins comprising the modular structure of the nuclear pore complex have been defined at atomic resolution. Here we report the crystal structure, at 2.6 Å resolution, of a heterotrimeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792969a7e7ac2733cc19deeaf6c9fd83
https://doi.org/10.1073/pnas.1112846108
https://doi.org/10.1073/pnas.1112846108
Autor:
Tomohiro Hitomi, Noriko Miwa, Hitoshi Jinnai, Kimihisa Yoshida, Toshihiro Akisue, Shun-ichi Nakamura
Publikováno v:
FEBS Letters. 422:108-112
A heat-stable activator for ADP-ribosylation factor (ARF)-dependent phospholipase D (PLD) was purified to near homogeneity from rat kidney cytosol by a sequential column chromatography. The purified activator has a molecular mass of 23 kDa on SDS-PAG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee3da6ea4bc5c14c77039745a6a5ad81
https://doi.org/10.1016/s0014-5793(97)01611-6
https://doi.org/10.1016/s0014-5793(97)01611-6
Autor:
Hitoshi Jinnai, Kimihisa Yoshida, Kiyoshi Shimooku, Toshihiro Akisue, Tomohiro Hitomi, Chiaki Ogino, Yasutomi Nishizuka, Shun-ichi Nakamura
Publikováno v:
FEBS Letters. 387:141-144
For activation of kidney membrane phospholipase D (PLD), cytosol is absolutely needed in addition to GTP-gamma-S. The active component of cytosol consists of three protein factors: ADP-ribosylation factor, RhoA, and a soluble 36-kDa protein. Any comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dc057482ea8f3a261d883c84bf069b
https://doi.org/10.1016/0014-5793(96)00483-8
https://doi.org/10.1016/0014-5793(96)00483-8
Autor:
Chiaki Ogino, Tomohiro Hitomi, Yoshimoto Kiyohara, Yasutomi Nishizuka, Shun-ichi Nakamura, Hitoshi Jinnai, Kimihisa Yoshida
Publikováno v:
Proceedings of the National Academy of Sciences. 93:4300-4304
Bovine kidney phospholipase D (PLD) was assayed by measuring the formation of phosphatidylethanol from added radioactive phosphatidylcholine (PtdCho) in the presence of ethanol, guanosine 5'-[gamma-thio]triphosphate, ammonium sulfate, and cytosol fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db088ed8c9b94ea8fc1f44eb83c1979
https://doi.org/10.1073/pnas.93.9.4300
https://doi.org/10.1073/pnas.93.9.4300
Autor:
Makoto Murakami, Kimihisa Yoshida, Ichiro Kudo, Yasutomi Nishizuka, Keizo Inoue, Yukio Sasaki, Yoshinori Asaoka
Publikováno v:
Proceedings of the National Academy of Sciences. 90:716-719
Both 2-lysophosphatidylcholine and cis-unsaturated fatty acids were previously shown to intensify agonist-induced cellular responses by enhancing the diacylglycerol-dependent activation of protein kinase C. Consistent with these observations, extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60626522d16d7352edd65d8ab9bb61e4
https://doi.org/10.1073/pnas.90.2.716
https://doi.org/10.1073/pnas.90.2.716
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6447-6451
2-Lysophosphatidylcholine (lysoPtdCho), a product of the hydrolysis of phosphatidylcholine catalyzed by phospholipase A2, greatly potentiates the activation of human resting T lymphocytes that is induced by a membrane-permeant diacylglycerol plus a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f27bfe8e4bfaaa958028db4279fade2
https://doi.org/10.1073/pnas.89.14.6447
https://doi.org/10.1073/pnas.89.14.6447
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6443-6446
Several cis-unsaturated fatty acids such as oleic, linoleic, linolenic, eicosapentaenoic, and docosahexaenoic acids added directly to intact human platelets greatly enhance protein kinase C activation as judged by the phosphorylation of its specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead014f4079520947065f7ff96248183
https://doi.org/10.1073/pnas.89.14.6443
https://doi.org/10.1073/pnas.89.14.6443
Autor:
Yasutomi Nishizuka, Kouji Ogita, Hiroshi Koide, Masahiro Oka, Kimihisa Yoshida, Tetsutaro Shinomura, Yoshinori Asaoka, Ushio Kikkawa
Publikováno v:
Journal of Nutritional Science and Vitaminology. 38:7-12
Signal-induced hydrolysis of inositol phospholipid produces two second messengers, diacylglycerol and inositol trisphosphate. Diacylglycerol activates protein kinase C, whereas inositol trisphosphate mobilizes Ca2+ from its internal store. Analogousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203c8d35668f8ed40ec1725cce6c363c
https://doi.org/10.3177/jnsv.38.special_7
https://doi.org/10.3177/jnsv.38.special_7
Publikováno v:
Proceedings of the National Academy of Sciences. 88:11062-11066
Although a single dose of phorbol 12-myristate 13-acetate (PMA) allowed HL-60 cells to differentiate to macrophages, a single dose of membrane-permeant diacylglycerol (DAG), 1,2-dioctanoylglycerol (1,2-DiC8), was normally insufficient to differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96058f79aac84b54593b8a619a2e23e8
https://doi.org/10.1073/pnas.88.24.11062
https://doi.org/10.1073/pnas.88.24.11062
Publikováno v:
Proceedings of the National Academy of Sciences. 88:8681-8685
DL-1,2-Dioctanoylglycerol (1,2-DiC8) added to human peripheral resting T lymphocytes was rapidly metabolized to produce octanoic acid and further to small molecules, probably by the action of diacylglycerol lipase and/or nonspecific esterase. Only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5603dd65442eb44327e9481b307e2e81
https://doi.org/10.1073/pnas.88.19.8681
https://doi.org/10.1073/pnas.88.19.8681