Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Kimihiko Kameyama"'
Publikováno v:
Journal of Receptors and Signal Transduction. 34:154-161
Directed evolution is a very popular strategy for improving biophysical properties and even for generating proteins with novel functions. Recent advances in combinatorial protein engineering mean it is now possible to develop protein scaffolds that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6caa5a99d77c74211ad23acfbc20aa
https://doi.org/10.3109/10799893.2013.865747
https://doi.org/10.3109/10799893.2013.865747
Autor:
Kaiwen He, Sandy Yu, Richard L. Huganir, Kogo Takamiya, Kimihiko Kameyama, David Wilen, Hey Kyoung Lee, Luciano Rossetti
Publikováno v:
Molecular and Cellular Neuroscience. 36:86-94
Phosphorylation of various AMPA receptor subunits can alter synaptic transmission and plasticity at excitatory glutamatergic synapses in the central nervous system. Here, we identified threonine-840 (T840) on the GluR1 subunit of AMPA receptors as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82c4961b5ffd1ef4ec6c08ea3369a6b
https://doi.org/10.1016/j.mcn.2007.06.003
https://doi.org/10.1016/j.mcn.2007.06.003
Publikováno v:
Neuropharmacology. 53:157-168
Melatonin is a hormone that controls circadian rhythms and seasonal behavioral changes in vertebrates. Recent studies indicate that melatonin participates in diverse physiological functions including the modulation of neural activities. Melatonin is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a55412731d91763a783d301f33ed31
https://doi.org/10.1016/j.neuropharm.2007.04.017
https://doi.org/10.1016/j.neuropharm.2007.04.017
Autor:
Muffadal Taher, Kimihiko Kameyama, Joshua T. Dudman, Wendy Macías, Molly E. Eaton, Amy K. Barczak, Richard L. Huganir, Anjali M. Rajadhyaksha, Christine Konradi
Publikováno v:
Journal of Neurochemistry. 87:922-934
Addictive drugs such as amphetamine and cocaine stimulate the dopaminergic system, activate dopamine receptors and induce gene expression throughout the striatum. The signal transduction pathway leading from dopamine receptor stimulation at the synap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089ddafdd959eeb2c0159e7c787edf07
https://doi.org/10.1046/j.1471-4159.2003.02067.x
https://doi.org/10.1046/j.1471-4159.2003.02067.x
Autor:
Takeshi Anzai, Keisuke Tsuzuki, Ken Inada, Nobuaki Yamada, Makoto Saji, Miwa Iwakuma, Sumio Hoka, Tomoyo Hayashi, Kimihiko Kameyama
Publikováno v:
Neuroscience Research. 46:41-51
To examine the role of Ca(2+) entry through AMPA receptors in the pathogenesis of the ischemia-induced cell death of hippocampal neurons, we delivered cDNA of Q/R site-unedited form (GluR2Q) of AMPA receptor subunit GluR2 in the hippocampus by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8075858ad3c3b3b6af78baed6c1edc0c
https://doi.org/10.1016/s0168-0102(03)00023-3
https://doi.org/10.1016/s0168-0102(03)00023-3
Publikováno v:
Folia Pharmacologica Japonica. 122:515-526
As glutamate is a dominant excitatory neurotransmitter in the central nervous system, glutamate receptors, and especially AMPA receptors, are located ubiquitously in all brain areas. In this paper, we reviewed recent advances of studies on AMPA recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb73bc2cc1b8067fb80316e3cbff630
https://doi.org/10.1254/fpj.122.515
https://doi.org/10.1254/fpj.122.515
Publikováno v:
Journal of Neurochemistry. 63:400-412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adcb35323c0e3076391968ad2b0efba
https://doi.org/10.1046/j.1471-4159.1994.63020400.x
https://doi.org/10.1046/j.1471-4159.1994.63020400.x
Publikováno v:
Nature. 405:955-959
Bidirectional changes in the efficacy of neuronal synaptic transmission, such as hippocampal long-term potentiation (LTP) and long-term depression (LTD), are thought to be mechanisms for information storage in the brain. LTP and LTD may be mediated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6571cb2bd3e48c71f3abed84028ce094
https://doi.org/10.1038/35016089
https://doi.org/10.1038/35016089
Autor:
Daniel A. Gschwend, Tatsuya Haga, Kimihiko Kameyama, Matthias U. Kassack, Richard C. Graul, Petra Högger, Wolfgang Sadee
Publikováno v:
AAPS PharmSci. 2:9-21
G-protein coupled receptor kinase 2 (GRK2) regulates the activity of many receptors. Because potent inhibitors of GRK2 are thus far limited to polyanionic compounds like heparin, we searched for new inhibitors with the aid of a molecular model of GRK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5383d389195a5afe490a0803c61db96d
https://doi.org/10.1208/ps020102
https://doi.org/10.1208/ps020102
Publikováno v:
Neuron. 21(5):1151-1162
Brief bath application of N-methyl-D-aspartate (NMDA) to hippocampal slices produces long-term synaptic depression (LTD) in CA1 that is (1) sensitive to postnatal age, (2) saturable, (3) induced postsynaptically, (4) reversible, and (5) not associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44914b18fcab4065055bac019a3174c