Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Kimihiko, Satoh"'
Autor:
Kimihiko Satoh
Publikováno v:
Cancer Medicine, Vol 13, Iss 18, Pp n/a-n/a (2024)
Abstract Background Cancer initiation has long been “unknowable” in biology and medicine. In 1987, however, Moore and our research group observed single hepatocytes and minifoci that were strongly positive for glutathione S‐transferase P‐form
Externí odkaz:
https://doaj.org/article/b5316639a0a047c8bc3904aaa75fb427
Autor:
Kimihiko, Satoh
Publikováno v:
Analytical Biochemistry. 643:114542
To analyze the initial carcinogenic changes that induce preneoplastic and neoplastic cell populations in the rat liver, a short-term in vivo promotion assay method was developed. Preneoplastic foci and nodules were quantitated with glutathione S-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dc36fc44a50701dacbedf44011da80
https://doi.org/10.1016/j.ab.2021.114542
https://doi.org/10.1016/j.ab.2021.114542
Autor:
Kimihiko Satoh
Publikováno v:
Life Sciences. 200:42-48
Aims To identify experimental conditions that induce preneoplastic cells positive for glutathione S-transferase P-form (GST-P) in the rat liver by new approaches, and analysis of the mechanism of cancer initiation based on the findings. Main methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55481b0b0a7a9c513d27e5be7e1443f
https://doi.org/10.1016/j.lfs.2018.02.041
https://doi.org/10.1016/j.lfs.2018.02.041
Publikováno v:
Internal Medicine
We present a case in which the accidental ingestion of a toothpick caused duodenal perforation and small intestinal obstruction. A 58-year-old man visited our emergency room with acute abdominal pain. Computed tomography (CT) showed obstructive ileus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf6b41c02ad3887f4869b60f78df71d
http://europepmc.org/articles/PMC5410475
http://europepmc.org/articles/PMC5410475
Publikováno v:
Cancer Sci
We investigated the process of induction of preneoplastic cells positive for glutathione S‐transferase P‐form (GST‐P) in the rat liver. AAF (2‐Acetylaminofluorene) mixed with normal rat chow at high concentration (0.04%) induced 517 000 ± 86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d900a754fc57ff4f3fe7c01c8b781f32
https://doi.org/10.1111/j.1349-7006.2012.02325.x
https://doi.org/10.1111/j.1349-7006.2012.02325.x
Autor:
Daishi Yamakawa, Kazuhiro Hosoi, Tatsusuke Sato, Kimihiko Satoh, Kazuyuki Kida, Makoto Hayakari, Hideaki Sugio
Publikováno v:
Japanese Journal of Clinical Oncology. 38:604-610
Background: We previously detected precursor cell populations of preneoplastic foci, GST-P þ /GGT 2 and GST-P þ /GGT þ minifoci, in rat liver in the initiation stage of chemical hepatocarcinogenesis, where GST-P and GGT represent glutathione S-tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c22cc0e6aa9342e75ea91f9537c66b
https://doi.org/10.1093/jjco/hyn080
https://doi.org/10.1093/jjco/hyn080
Autor:
Masayoshi Imagawa, Soken Tsuchiya, Yukihiko Sugimoto, Shigero Tamba, Ayako Naganawa, Yasushi Okuno, Gozoh Tsujimoto, Kimihiko Satoh, Masashi Misonou, Jun ichi Nishikawa, Shigehiro Osada, Tsutomu Nishihara
Publikováno v:
Toxicology Letters. 167:106-113
Glutathione-S-transferase placental form (GST-P) is markedly and specifically inducible in rat chemical hepatocarcinogenesis and is a reliable marker protein for pre-neoplasia. To gain insights into the molecular mechanisms at the early stage of hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9518f616d5e3c06d628577dd4df5c7d6
https://doi.org/10.1016/j.toxlet.2006.08.014
https://doi.org/10.1016/j.toxlet.2006.08.014
Publikováno v:
International Journal of Cancer. 115:711-716
An improved staining method for gamma-glutamyltranspeptidase (GGT) was developed using Vibratome-prepared microslices. Microscopic precursor cell populations of preneoplastic foci positive for the marker enzyme were detectable sequentially in rat liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1633816eefcfa90d57750fbf2e1ec979
https://doi.org/10.1002/ijc.20979
https://doi.org/10.1002/ijc.20979
Autor:
Hiroshi Izumi, Shigeki Tsuchida, Junpei Asano, Takehiko Yamazaki, Toshihiro Kudoh, Makoto Hayakari, Kimihiko Satoh
Publikováno v:
Peptides. 24:1075-1082
Leu-Val-Val-hemorphin-7 (LVV-H7, LVVYPWTQRY), an opioid peptide, was found to be hydrolyzed sequentially by rat brain angiotensin-converting enzyme (ACE) in three steps through dipeptidyl carboxypeptidase activity. The kinetic constants evaluated wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d725ac89e3ed098e80535ca0f8a7feaf
https://doi.org/10.1016/s0196-9781(03)00178-5
https://doi.org/10.1016/s0196-9781(03)00178-5
Autor:
Kimihiko Satoh, Ichiro Hatayama
Publikováno v:
Carcinogenesis. 23:1193-1198
The molecular mechanism of the specific expression of glutathione S-transferase P-form (GST-P) in the rat hepatic preneoplastic foci and "GST-P-positive" single cells requires elucidation. Immunochemical and stereological analyses revealed that the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd99ed68c5441c1f76304e93de5a2769
https://doi.org/10.1093/carcin/23.7.1193
https://doi.org/10.1093/carcin/23.7.1193