Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Kimi, Araki"'
Autor:
Yumeng Wu, Tatsuya Yano, Takayuki Enomoto, Atena Endo, Seiji Okada, Kimi Araki, Nobuaki Shiraki, Shoen Kume
Publikováno v:
Cell Transplantation, Vol 33 (2024)
Type 1 diabetes mellitus (T1DM) affects 8.4 million people worldwide, with patients primarily relying on exogenous insulin injections to maintain blood glucose levels. Islet transplantation via the portal vein has allowed for the direct internal rele
Externí odkaz:
https://doaj.org/article/3ee0e64877004664bcd634a32b71e517
Autor:
Saori Yoshimura, Ryuki Shimada, Koji Kikuchi, Soichiro Kawagoe, Hironori Abe, Sakie Iisaka, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Naoki Tani, Takashi Ohba, Eiji Kondoh, Tomohide Saio, Kimi Araki, Kei-ichiro Ishiguro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Meiotic prophase progression is differently regulated in males and females. In males, pachytene transition during meiotic prophase is accompanied by robust alteration in gene expression. However, how gene expression is regulated differently
Externí odkaz:
https://doaj.org/article/6a02458e68fa47fb9b60342236eeb4b5
Autor:
Naoto Yoshimura, Ryusho Kariya, Masaki Shimada, Makoto Tateyama, Hideto Matsunaga, Yuto Shibata, Shuntaro Tanimura, Kosei Takata, Takahiro Arima, Junki Kawakami, Kazuya Maeda, Yuko Fukuma, Masaru Uragami, Katsumasa Ideo, Kazuki Sugimoto, Ryuji Yonemitsu, Kozo Matsushita, Satoshi Hisanaga, Masaki Yugami, Yusuke Uehara, Tetsuro Masuda, Takayuki Nakamura, Takuya Tokunaga, Tatsuki Karasugi, Takanao Sueyoshi, Hiro Sato, Yoichiro Iwakura, Kimi Araki, Eisuke Kobayashi, Seiji Okada, Takeshi Miyamoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Osteosarcoma is rare but is the most common bone tumor. Diagnostic tools such as magnetic resonance imaging development of chemotherapeutic agents have increased the survival rate in osteosarcoma patients, although 5-year survival has platea
Externí odkaz:
https://doaj.org/article/ed559e9c0ee0472ab0240adfebdfaea7
Autor:
Tsuyoshi Kadomatsu, Chiaki Hara, Ryoma Kurahashi, Haruki Horiguchi, Jun Morinaga, Keishi Miyata, Sohtaro Kurano, Hisashi Kanemaru, Satoshi Fukushima, Kimi Araki, Masaya Baba, W. Marston Linehan, Tomomi Kamba, Yuichi Oike
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2637-2658 (2023)
Loss or downregulation of major histocompatibility complex class I (MHC‐I) contributes to tumor immune evasion. We previously demonstrated that angiopoietin‐like protein 2 (ANGPTL2) promotes tumor progression using a Xp11.2 translocation renal ce
Externí odkaz:
https://doaj.org/article/77efc53feca24f4d9bfc397aad582af1
Autor:
Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Meiosis is differently regulated in males and females. In females, germ cells initiate meiosis within a limited time period in the fetal ovary and undergo a prolonged meiotic arrest until puberty. However, how meiosis initiation is coordinat
Externí odkaz:
https://doaj.org/article/b9127f032d2d4588b364b73be9cdf150
Autor:
Yuichi Tsuchiya, Takao Seki, Kenta Kobayashi, Sachiko Komazawa-Sakon, Shigeyuki Shichino, Takashi Nishina, Kyoko Fukuhara, Kenichi Ikejima, Hidenari Nagai, Yoshinori Igarashi, Satoshi Ueha, Akira Oikawa, Shinya Tsurusaki, Soh Yamazaki, Chiharu Nishiyama, Tetuo Mikami, Hideo Yagita, Ko Okumura, Taketomo Kido, Atsushi Miyajima, Kouji Matsushima, Mai Imasaka, Kimi Araki, Toru Imamura, Masaki Ohmuraya, Minoru Tanaka, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Liver fibrosis results from chronic liver injury triggered by factors such as viral infection, excess alcohol intake, and lipid accumulation. However, the mechanisms underlying liver fibrosis are not fully understood. Here, we demonstrate th
Externí odkaz:
https://doaj.org/article/634090b816f84d4c88ef880ddf06cc84
Autor:
Takuya Nagai, Tomohisa Sekimoto, Syuji Kurogi, Tomomi Ohta, Shihoko Miyazaki, Yoichiro Yamaguchi, Takuya Tajima, Etsuo Chosa, Mai Imasaka, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Narantsog Choijookhuu, Katsuaki Sato, Yoshitaka Hishikawa, Taro Funamoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Bone remodeling is an extraordinarily complex process involving a variety of factors, such as genetic, metabolic, and environmental components. Although genetic factors play a particularly important role, many have not been identified. In th
Externí odkaz:
https://doaj.org/article/0e6015e1753c41daacaf7b76f7d2d5ac
Autor:
Shin Murai, Kanako Takakura, Kenta Sumiyama, Kenta Moriwaki, Kenta Terai, Sachiko Komazawa-Sakon, Takao Seki, Yoshifumi Yamaguchi, Tetuo Mikami, Kimi Araki, Masaki Ohmuraya, Michiyuki Matsuda, Hiroyasu Nakano
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The SMART (MLKL-activation reporter) system FRET biosensor allows for necroptosis assessment in primary cells and in a mouse model of cisplatininduced AKI.
Externí odkaz:
https://doaj.org/article/6504ff9ca71d4ea289906bdb29e18461
Autor:
Kaori Oka, Shusuke Fujioka, Yoshimi Kawamura, Yoshihiro Komohara, Takeshi Chujo, Koki Sekiguchi, Yuki Yamamura, Yuki Oiwa, Natsuko Omamiuda-Ishikawa, Shohei Komaki, Yoichi Sutoh, Satoko Sakurai, Kazuhito Tomizawa, Hidemasa Bono, Atsushi Shimizu, Kimi Araki, Takuya Yamamoto, Yasuhiro Yamada, Hiroyuki Oshiumi, Kyoko Miura
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Naked mole rats are found to be resistant to cancer development through dampened inflammatory response due to genetically determined impaired necroptosis, with essential necroptosis genes RIPK3 and MLKL containing mutations causing premature stop cod
Externí odkaz:
https://doaj.org/article/9dd13d092962438287167bbbff17d001
Autor:
Yuki Horisawa-Takada, Chisato Kodera, Kazumasa Takemoto, Akihiko Sakashita, Kenichi Horisawa, Ryo Maeda, Ryuki Shimada, Shingo Usuki, Sayoko Fujimura, Naoki Tani, Kumi Matsuura, Tomohiko Akiyama, Atsushi Suzuki, Hitoshi Niwa, Makoto Tachibana, Takashi Ohba, Hidetaka Katabuchi, Satoshi H. Namekawa, Kimi Araki, Kei-Ichiro Ishiguro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The authors add to our knowledge of the transcriptional regulation of the meiotic program in mice spermatocytes, showing ZFP541 regulates meiotic prophase and transition to the division phase by being the target for upstream factors MEIOSIN/STRA8.
Externí odkaz:
https://doaj.org/article/ae1c01342b7a40449dbc60cd3eaf9267