Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kimheak Sao"'
Autor:
Kimheak Sao, Makarand V. Risbud
Publikováno v:
Neurospine, Vol 21, Iss 1, Pp 162-178 (2024)
Proteoglycans through their sulfated glycosaminoglycans regulate cell-matrix signaling during tissue development, regeneration, and degeneration processes. Large extracellular proteoglycans such as aggrecan, versican, and perlecan are especially impo
Externí odkaz:
https://doaj.org/article/edd25b60f1604dba9d959de519f18d51
Autor:
Takashi Ohnishi, Victoria Tran, Kimheak Sao, Pranay Ramteke, William Querido, Ruteja A. Barve, Koen van de Wetering, Makarand V. Risbud
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-16 (2023)
Abstract Pathological mineralization of intervertebral disc is debilitating and painful and linked to disc degeneration in a subset of human patients. An adenosine triphosphate efflux transporter, progressive ankylosis (ANK) is a regulator of extrace
Externí odkaz:
https://doaj.org/article/52af5c97e2af4fe581d193748d0a3806
Autor:
Takashi Ohnishi, Victoria Tran, Kimheak Sao, Pranay Ramteke, William Querido, Koen van de Wetering, Makarand Risbud
Pathological mineralization of intervertebral disc is debilitating and painful and linked to disc degeneration in a subset of human patients. An adenosine triphosphate transporter, progressive ankylosis (ANK) is a regulator of extracellular inorganic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd19d99ae9b9d208ab63f0955da4dd1
https://doi.org/10.21203/rs.3.rs-2336837/v1
https://doi.org/10.21203/rs.3.rs-2336837/v1
Autor:
Kimheak Sao, Ryan J. Petrie, Changsong Yang, Nicole M Naranjo, Tatyana Svitkina, Donna McKeon, Shivani Patel
Publikováno v:
Molecular Biology of the Cell
Human fibroblasts can switch between lamellipodia-dependent and -independent migration mechanisms on two-dimensional surfaces and in three-dimensional (3D) matrices. RhoA GTPase activity governs the switch from low-pressure lamellipodia to high-press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1844549c1870c34babc56ec6b2fe5210
https://doi.org/10.1091/mbc.e20-04-0227
https://doi.org/10.1091/mbc.e20-04-0227
Autor:
Kimheak Sao, Claire E. Witherel, Becky K. Brisson, Biao Han, Susan W. Volk, Lin Han, Kara L. Spiller, Ryan J. Petrie
Publikováno v:
Biomaterials
Aberrant extracellular matrix (ECM) assembly surrounding implanted biomaterials is the hallmark of the foreign body response, in which implants become encapsulated in thick fibrous tissue that prevents their proper function. While macrophages are kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b549fa18e4f1636b88163b79733a4b03
https://doi.org/10.1101/2020.08.21.261933
https://doi.org/10.1101/2020.08.21.261933
Autor:
James E. Bear, Richard F. Loeser, Veronica Ulici, Brian O. Diekman, Alexandra C. Doolittle, Irving M. Shapiro, Jeremy D. Rotty, Steven Tessier, Kimheak Sao, Makarand V. Risbud
Publikováno v:
JCI insight. 5(4)
Extracellular matrix and osmolarity influence the development and homeostasis of skeletal tissues through Rho GTPase–mediated alteration of the actin cytoskeleton. This study investigated whether the actin-branching Arp2/3 complex, a downstream eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b44d40199f5b5c98064132199cfa9e8
https://pubmed.ncbi.nlm.nih.gov/31961823
https://pubmed.ncbi.nlm.nih.gov/31961823
Autor:
Galina Schevzov, Andrew D. Doyle, Ryan J. Petrie, Tia M. Jones, Yun Chen, Kimheak Sao, Debonil Maity, Peter W. Gunning
Publikováno v:
Molecular Biology of the Cell
Two-dimensional (2D) substrate rigidity promotes myosin II activity to increase traction force in a process negatively regulated by tropomyosin (Tpm) 2.1. We recently discovered that actomyosin contractility can increase intracellular pressure and sw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8123062da5c369774587b90173c4416
https://pubmed.ncbi.nlm.nih.gov/30865560
https://pubmed.ncbi.nlm.nih.gov/30865560
Publikováno v:
International review of cell and molecular biology. 337
Intracellular pressure, generated by actomyosin contractility and the directional flow of water across the plasma membrane, can rapidly reprogram cell shape and behavior. Recent work demonstrates that cells can generate intracellular pressure with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b84ef5752861f658609aac586289012c
https://pubmed.ncbi.nlm.nih.gov/29551161
https://pubmed.ncbi.nlm.nih.gov/29551161
Intracellular pressure, generated by actomyosin contractility and the directional flow of water across the plasma membrane, can rapidly reprogram cell shape and behavior. Recent work demonstrates that cells can generate intracellular pressure with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdda27eb2b67ece03c47a8fc19873b12
https://doi.org/10.1016/bs.ircmb.2017.12.005
https://doi.org/10.1016/bs.ircmb.2017.12.005