A cross-sectional analysis identifies a low prevalence of Plasmodium ovale  species   infections in symptomatic and asymptomatic individuals in Kilifi county, Kenya.

Autor: Akinyi MY; KEMRI-Wellcome Trust Research Programme, Kenya Medical Research Institute, Kilifi, P.O. Box 230, 80108, Kenya.; Institute of Primate Research, National Museums of Kenya, Nairobi, 24481-00502, Kenya., Chifwete M; KEMRI-Wellcome Trust Research Programme, Kenya Medical Research Institute, Kilifi, P.O. Box 230, 80108, Kenya.; Pwani University, Kilifi, P.O. Box 195-80108, Kenya., Ndwiga L; KEMRI-Wellcome Trust Research Programme, Kenya Medical Research Institute, Kilifi, P.O. Box 230, 80108, Kenya., Kimenyi KM; KEMRI-Wellcome Trust Research Programme, Kenya Medical Research Institute, Kilifi, P.O. Box 230, 80108, Kenya.; Center for Biotechnology and Bioinformatics, University of Nairobi, Kilifi, P.O Box 30197-00100, Kenya., Osoti V; KEMRI-Wellcome Trust Research Programme, Kenya Medical Research Institute, Kilifi, P.O. Box 230, 80108, Kenya., Ochola-Oyier LI; KEMRI-Wellcome Trust Research Programme, Kenya Medical Research Institute, Kilifi, P.O. Box 230, 80108, Kenya.

Publikováno v: Wellcome open research [Wellcome Open Res] 2024 Sep 17; Vol. 7, pp. 207. Date of Electronic Publication: 2024 Sep 17 (Print Publication: 2022).

Amplicon Sequencing as a Potential Surveillance Tool for Complexity of Infection and Drug Resistance Markers in Plasmodium falciparum Asymptomatic Infections.

Autor: Wamae K; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya., Kimenyi KM; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya.; Centre for Biotechnology and Bioinformatics, University of Nairobi, Nairobi, Kenya., Osoti V; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya., de Laurent ZR; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya., Ndwiga L; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya., Kharabora O; Division of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Hathaway NJ; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Bailey JA; Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA., Juliano JJ; Division of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.; Curriculum in Genetics and Molecular Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Bejon P; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Ochola-Oyier LI; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2022 Sep 13; Vol. 226 (5), pp. 920-927.

Targeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya.

Autor: Osoti V; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya., Akinyi M; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya.; Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya., Wamae K; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya., Kimenyi KM; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya.; Department of Biochemistry, University of Nairobi, Nairobi, Kenya., de Laurent Z; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya., Ndwiga L; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya., Gichuki P; Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institutegrid.33058.3d, Nairobi, Kenya., Okoyo C; Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institutegrid.33058.3d, Nairobi, Kenya., Kepha S; Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institutegrid.33058.3d, Nairobi, Kenya., Mwandawiro C; Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institutegrid.33058.3d, Nairobi, Kenya., Kandie R; Division of National Malaria Programme, Ministry of Health, Nairobi, Kenya., Bejon P; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Snow RW; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Ochola-Oyier LI; KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Apr 19; Vol. 66 (4), pp. e0194521. Date of Electronic Publication: 2022 Mar 10.

A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.

Autor: Ndwiga L; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya., Kimenyi KM; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya; Centre for Biotechnology and Bioinformatics, University of Nairobi, Nairobi, Kenya., Wamae K; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya., Osoti V; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya., Akinyi M; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya; Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya., Omedo I; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, United Kingdom., Ishengoma DS; National Institute for Medical Research (NIMR), Dar es Salaam, Tanzania., Duah-Quashie N; Department of Epidemiology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana., Andagalu B; United States Army Medical Research Directorate-Africa, Kenya Medical Research Institute/Walter Reed Project, Kisumu, Kenya., Ghansah A; Department of Parasitology, Noguchi Memorial Institute for Medical Research (NMIMR), Accra, Ghana., Amambua-Ngwa A; Medical Research Council Unit the Gambia at LSHTM, Banjul, Gambia., Tukwasibwe S; Infectious Diseases Research Collaboration, Kampala, Uganda., Tessema SK; Africa Centres for Disease Control, Addis Ababa, Ethiopia., Karema C; Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Quality and Equity Healthcare, Kigali, Rwanda., Djimde AA; Malaria Research and Training Centre, University of Science, Techniques and Technologies of Bamako, Bamako, Mali., Dondorp AM; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Raman J; Centre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Disease, Sandringham, Gauteng, South Africa; Wits Research Institute for Malaria, Univerisity of Witwatersrand, Johannesburg, South Africa., Snow RW; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Bejon P; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Ochola-Oyier LI; KEMRI-Wellcome Trust Collaborative Programme, P.O. Box 230, 80108, Kilifi, Kenya. Electronic address: LiOchola@kemri-wellcome.org.

Publikováno v: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2021 Aug; Vol. 16, pp. 155-161. Date of Electronic Publication: 2021 Jun 10.

Understanding P. falciparum Asymptomatic Infections: A Proposition for a Transcriptomic Approach.

Autor: Kimenyi KM; KEMRI-Wellcome Trust Research Programme, CGMRC, Kilifi, Kenya.; Centre for Biotechnology and Bioinformatics, University of Nairobi, Nairobi, Kenya., Wamae K; KEMRI-Wellcome Trust Research Programme, CGMRC, Kilifi, Kenya., Ochola-Oyier LI; KEMRI-Wellcome Trust Research Programme, CGMRC, Kilifi, Kenya.; Pwani University Bioscience Research Centre, Pwani University, Kilifi, Kenya.

Publikováno v: Frontiers in immunology [Front Immunol] 2019 Oct 15; Vol. 10, pp. 2398. Date of Electronic Publication: 2019 Oct 15 (Print Publication: 2019).