Aging-related defects in macrophage function are driven by MYC and USF1 transcriptional programs.

Autor: Moss CE; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK; Healthy Lifespan Institute, University of Sheffield, Sheffield, UK., Johnston SA; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Kimble JV; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK; Healthy Lifespan Institute, University of Sheffield, Sheffield, UK., Clements M; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Codd V; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; National Institute for Healthcare Research, Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Hamby S; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; National Institute for Healthcare Research, Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Goodall AH; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; National Institute for Healthcare Research, Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Deshmukh S; School of Biosciences, University of Sheffield, Sheffield, UK., Sudbery I; School of Biosciences, University of Sheffield, Sheffield, UK., Coca D; Healthy Lifespan Institute, University of Sheffield, Sheffield, UK; Department of Autonomic Control and Systems Engineering, University of Sheffield, Sheffield, UK., Wilson HL; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK; Healthy Lifespan Institute, University of Sheffield, Sheffield, UK. Electronic address: h.l.wilson@sheffield.ac.uk., Kiss-Toth E; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK; Healthy Lifespan Institute, University of Sheffield, Sheffield, UK; Biological Research Centre, Szeged, Hungary. Electronic address: e.kiss-toth@sheffield.ac.uk.

Publikováno v: Cell reports [Cell Rep] 2024 Apr 23; Vol. 43 (4), pp. 114073. Date of Electronic Publication: 2024 Apr 04.

Human monocyte subtype expression of neuroinflammation- and regeneration-related genes is linked to age and sex.

Autor: Tampé, Juliane F.¹ (AUTHOR) juliane.tampe@med.lu.se, Monni, Emanuela¹ (AUTHOR), Palma-Tortosa, Sara¹ (AUTHOR), Brogårdh, Emil² (AUTHOR), Böiers, Charlotta³ (AUTHOR), Lindgren, Arne G.² (AUTHOR), Kokaia, Zaal¹ (AUTHOR) zaal.kokaia@med.lu.se

Publikováno v: PLoS ONE. 10/30/2024, Vol. 19 Issue 10, p1-21. 21p.