Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kimberly T. Fowler"'
Autor:
Kimberly T. Fowler, Ong Moua, Janet M. Wenzlau, Liping Yu, Howard W. Davidson, John C. Hutton, Yu Liu, Jay A. Walters, George S. Eisenbarth, Sampathkumar Rangasamy
Publikováno v:
Diabetes
OBJECTIVE—Zinc transporter eight (SLC30A8) is a major target of autoimmunity in human type 1A diabetes and is implicated in type 2 diabetes in genome-wide association studies. The type 2 diabetes nonsynonymous single nucleotide polymorphism (SNP) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cbbb242e68bbb6f67b015a83cb65e7
http://europepmc.org/articles/PMC2551679
http://europepmc.org/articles/PMC2551679
Autor:
Kimberly T. Fowler, Norma W. Andrews, David R. Liston, Koichi Kobayashi, Richard A. Flavell, Sabyasachi Chakrabarti, Katsuya Miyake, Carolyn Marks, Fred S. Gorelick
Publikováno v:
The Journal of Cell Biology
Members of the synaptotagmin family have been proposed to function as Ca2+ sensors in membrane fusion. Syt VII is a ubiquitously expressed synaptotagmin previously implicated in plasma membrane repair and Trypanosoma cruzi invasion, events which are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dec93e99f362e34f889e251173b3d7
https://doi.org/10.1083/jcb.200305131
https://doi.org/10.1083/jcb.200305131
Autor:
Iñigo Martinez, Sabyasachi Chakrabarti, Jennifer Morehead, Turid Hellevik, Kimberly T. Fowler, Norma W. Andrews
Publikováno v:
The Journal of Cell Biology
Synaptotagmins (Syts) are transmembrane proteins with two Ca(2+)-binding C(2) domains in their cytosolic region. Syt I, the most widely studied isoform, has been proposed to function as a Ca(2+) sensor in synaptic vesicle exocytosis. Several of the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d09370e0fbe662391654f516642d88f
https://doi.org/10.1083/jcb.148.6.1141
https://doi.org/10.1083/jcb.148.6.1141
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(3)
The Ca2+ sensor synaptotagmin (Syt) VII regulates the exocytosis of conventional lysosomes in several cell types. In CTLs, the Ca2+-regulated exocytosis of lytic granules/secretory lysosomes is responsible for the perforin/granzyme-mediated lysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39975bd207d99417f34a1e13f15f4320
https://pubmed.ncbi.nlm.nih.gov/17237398
https://pubmed.ncbi.nlm.nih.gov/17237398
Autor:
Sabyasachi Chakrabarti, Swathi K. Rao, Kimberly T. Fowler, Elisabet V. Caler, Norma W. Andrews
Publikováno v:
The Journal of Experimental Medicine
The intracellular protozoan parasite Trypanosoma cruzi causes Chagas' disease, which affects millions of people in Latin America. T. cruzi enters a large number of cell types by an unusual mechanism that involves Ca2+-triggered fusion of lysosomes wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d64793ba6d14b40fb1a1525427a531
https://pubmed.ncbi.nlm.nih.gov/11342594
https://pubmed.ncbi.nlm.nih.gov/11342594