Výsledky vyhledávání - "Kimberly Spence"

Avoiding NICU Transfers for Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS): A Quality Improvement Initiative to Manage NOWS on the Mother-baby Unit

Autor: Rebecca Boedeker, Justin B. Josephsen, Mary Harhausen, Kimberly Spence, Gauri Kaushal, Paula Buchanan

Publikováno v: Journal of Addiction Medicine. 14:401-408

OBJECTIVES To reduce transfers to the neonatal intensive care unit (NICU) for neonates with opioid withdrawal while also reducing length of stay and pharmacologic intervention, and maintaining standards of safety. PATIENTS AND METHODS This was a sing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7f6a8ab9eed88e35f3eccd4fe59c8a6
https://doi.org/10.1097/adm.0000000000000607

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Factors Influencing Outcomes After Cardiac Intervention in Infants with Trisomy 13 and 18

Autor: Renuka E. Peterson, Charles B. Huddleston, Kimberly Spence, Andrew C. Fiore, Nandini Calamur

Publikováno v: Pediatric cardiology. 39(1)

Cardiac intervention remains controversial in patients with trisomy 13 and 18 and little is known about factors that may affect outcomes. The goal of this study was to evaluate preoperative factors and surgical approach with respect to outcomes in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce09c26cbbf1bcd0bb461378e7ddd659
https://pubmed.ncbi.nlm.nih.gov/28948390

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Pilot trial of late booster doses of surfactant for ventilated premature infants

Autor: Aaron Hamvas, Anna Maria Hibbs, Robin H. Steinhorn, William E Truog, David J. Durand, K. W. Lu, Sherry E. Courtney, Roberta A. Ballard, Anne Marie Reynolds, Kimberly Spence, Philip L. Ballard, Rita M. Ryan, Eric C. Eichenwald, Jeffrey D. Merrill

Publikováno v: Journal of Perinatology. 31:599-606

Many premature infants at risk for bronchopulmonary dysplasia experience episodes of surfactant dysfunction with reduced surfactant protein B (SP-B). In this study, we investigated the safety and responses to booster doses of surfactant. A total of 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd7392d38baece056fea98d383455da
https://doi.org/10.1038/jp.2010.210

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Measurement of Human Surfactant Protein-B Turnover in Vivo from Tracheal Aspirates Using Targeted Proteomics

Autor: F. Sessions Cole, Paolo Vicini, Kimberly Spence, Daniela M. Tomazela, Elizabeth Hanson, Bruce W. Patterson, Aaron Hamvas, David H. Salinger, Tiffany B. Kanion, Hugh Barret, Hillary B. Heins, Michael J. MacCoss

Publikováno v: Analytical Chemistry. 82:2561-2567

We describe a method to measure protein synthesis and catabolism in humans without prior purification and use the method to measure the turnover of surfactant protein-B (SP-B). SP-B, a lung-specific, hydrophobic protein essential for fetal-neonatal r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cdf3a36caed40efcd0c5635cfaf8cf
https://doi.org/10.1021/ac1001433

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High-flow nasal cannula as a device to provide continuous positive airway pressure in infants

Autor: Kimberly Spence, R McGonigle, D Murphy, R A Kilani, C Kilian

Publikováno v: Journal of Perinatology. 27:772-775

Objective To measure the intrapharyngeal pressure (IPP) generated by high-flow nasal cannula (HFNC) at varying flow rates up to 5 l min(-1). Study design We studied 14 infants on HFNC or NCPAP using IPP manometry to measure the IPP generated at flows

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d904cb6a8d28b9abc0fd390fba40a27
https://doi.org/10.1038/sj.jp.7211828

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Substrate utilization and kinetics of surfactant metabolism in evolving bronchopulmonary dysplasia

Autor: Aaron Hamvas, Kimberly Spence, Bruce W. Patterson, James C.G. Zozobrado

Publikováno v: The Journal of Pediatrics. 147:480-485

Objectives To use stable isotopically labeled precursors of pulmonary surfactant phospholipids to measure precursor utilization and surfactant turnover in premature infants who required mechanical ventilation at birth, 2 weeks, and >4 weeks of age. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ab86966159304e39fee856a96c2745
https://doi.org/10.1016/j.jpeds.2005.04.039

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Metabolic kinetics of pulmonary surfactant in newborn infants using endogenous stable isotope techniques

Autor: Aaron Hamvas, Bruce W. Patterson, Kimberly Spence, Assaad Merchak, Kajsa Bohlin, Luc J. I. Zimmermann, James C.G. Zozobrado, Virgilio P. Carnielli

Publikováno v: Journal of Lipid Research, Vol 46, Iss 6, Pp 1257-1265 (2005)

We compared kinetic indices of pulmonary surfactant metabolism in premature infants (n = 41) with respect to i) tracer ([1-(13)C1]acetate, [U-(13)C6]glucose, and [1,2,3,4-(13)C4] palmitate), ii) phospholipid (PL) pool (total PLs or disaturated PLs),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1d58072e3690d1ec6866f9f7518967
http://www.sciencedirect.com/science/article/pii/S0022227520330303

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