Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kimberly S. Paul"'
Autor:
Lawrence Fernando, Jing Echesabal-Chen, Murphy Miller, Rhonda Reigers Powell, Terri Bruce, Apurba Paul, Nava Poudyal, Joshua Saliutama, Kristina Parman, Kimberly S. Paul, Alexis Stamatikos
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1730 (2024)
Trypanosoma brucei causes African trypanosomiasis in humans. Infection with T. brucei elicits a potent pro-inflammatory immune response within infected human hosts, and this response is thought to at least be partially due to Toll-like receptor (TLR)
Externí odkaz:
https://doaj.org/article/749ae7d287a74d17a759d12de42bd4da
Autor:
Nava Raj Poudyal, Kimberly S. Paul
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Trypanosoma brucei spp. causes African Sleeping Sickness in humans and nagana, a wasting disease, in cattle. As T. brucei goes through its life cycle in its mammalian and insect vector hosts, it is exposed to distinct environments that differ in thei
Externí odkaz:
https://doaj.org/article/4620f4c1ed194da887d40d2e8b69f5a9
Autor:
Lucie Kafková, Chengjian Tu, Kyle L. Pazzo, Kyle P. Smith, Erik W. Debler, Kimberly S. Paul, Jun Qu, Laurie K. Read
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT In Trypanosoma brucei and related kinetoplastid parasites, transcription of protein coding genes is largely unregulated. Rather, mRNA binding proteins, which impact processes such as transcript stability and translation efficiency, are the p
Externí odkaz:
https://doaj.org/article/647e168636894a55bb8debea108ceecc
Publikováno v:
mSphere, Vol 3, Iss 4 (2018)
ABSTRACT To satisfy its fatty acid needs, the extracellular eukaryotic parasite Trypanosoma brucei relies on two mechanisms: uptake of fatty acids from the host and de novo synthesis. We hypothesized that T. brucei modulates fatty acid synthesis in r
Externí odkaz:
https://doaj.org/article/256981ecbf8e46b4854349ddfa8a720e
Autor:
Nava R. Poudyal, Kimberly S. Paul
Publikováno v:
The FASEB Journal. 36
Autor:
Kimberly S. Paul, Joshua Saliutama
Publikováno v:
The FASEB Journal. 35
Autor:
Lucie Kafková, Kyle L. Pazzo, Laurie K. Read, Kyle P. Smith, Kimberly S. Paul, Erik W. Debler, Jun Qu, Chengjian Tu
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
mBio, Vol 9, Iss 6, p e02430-18 (2018)
mBio
mBio, Vol 9, Iss 6, p e02430-18 (2018)
mBio
Trypanosoma brucei infection causes human African trypanosomiasis, also known as sleeping sickness, a disease with a nearly 100% fatality rate when untreated. Current drugs are expensive, toxic, and highly impractical to administer, prompting the com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d5ec1c7a7e530759053ed2a2fe9185
https://ora.ox.ac.uk/objects/uuid:0b88e9a6-715c-440b-aed9-f84cc0a745f6
https://ora.ox.ac.uk/objects/uuid:0b88e9a6-715c-440b-aed9-f84cc0a745f6
Publikováno v:
mSphere
Trypanosoma brucei is a eukaryotic parasite that causes African sleeping sickness. T. brucei is transmitted by the blood-sucking tsetse fly. In order to adapt to its two very different hosts, T. brucei must sense the host environment and alter its me
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance. 2:225-229
The current pharmacopeia to treat the lethal human and animal diseases caused by the protozoan parasite Trypanosoma brucei remains limited. The parasite’s ability to undergo antigenic variation represents a considerable barrier to vaccine developme
Autor:
Patrick A. Vigueira, Kylie M. Smith, Michael J. Childress, C. Kaighn Morlok, Kimberly S. Paul, Kirk J. Parmenter, Jennifer A. Micklewright
Publikováno v:
Estuaries and Coasts. 36:174-191
Blue crab, Callinectes sapidus, commercial landings in the USA have been declining at an alarming rate. In South Carolina, these declines are significantly correlated with years of decreased rainfall and elevated salt marsh salinity. Previous studies