Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kimberly R. Coenen"'
Autor:
Kimberly R. Coenen, R. Richard Pencek, Larry L. Swift, Jane Shearer, Jeffrey N. Rottman, David H. Wasserman
Publikováno v:
Lipids. 43:703-711
Insulin resistance is characterized by increased metabolic uptake of fatty acids. Accordingly, techniques to examine in vivo shifts in fatty acid metabolism are of value in both clinical and experimental settings. Partially metabolizable long chain f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8961a9691602a45d6cbb1a3b8d06516
https://doi.org/10.1007/s11745-008-3183-4
https://doi.org/10.1007/s11745-008-3183-4
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 294:E284-E290
Previous studies have demonstrated that macrophage-derived apolipoprotein E (apoE) reduces atherosclerotic lesion formation in lean apoE-deficient (−/−) mice. apoE has also been demonstrated to play a role in adipocyte differentiation and lipid a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbe56deef7738068bc339b85022c387
https://doi.org/10.1152/ajpendo.00601.2007
https://doi.org/10.1152/ajpendo.00601.2007
Autor:
Alyssa H. Hasty, Kimberly R. Coenen
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 293:E492-E499
Obesity is increasing at an alarming rate, and its related disorders are placing a considerable strain on our healthcare system. Although they are not always coincident, obesity is often accompanied by hyperlipidemia. Both obesity and hyperlipidemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec31a3d2f469c2f3bcea796d3fcd5d9
https://doi.org/10.1152/ajpendo.00171.2007
https://doi.org/10.1152/ajpendo.00171.2007
Autor:
Thomas M. Morgan, M.S.H.S. Shari L. Barkin M.D., Mary S. Dietrich, C.P.N.P. Sharon M. Karp Ph.D., R.D. Kimberly R. Coenen Ph.D., Sabina B. Gesell
Publikováno v:
Clinical and translational science. 4(5)
Obesity disproportionately affects Latina women. Common genetic variants are convincingly associated with body mass index (BMI) and may be used to create genetic risk scores (GRS) for obesity that could define genetically influenced forms of obesity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de53be9e208541b6bea9245abaf1f82
https://pubmed.ncbi.nlm.nih.gov/22029802
https://pubmed.ncbi.nlm.nih.gov/22029802
Autor:
David H. Wasserman, Marnie L. Gruen, Kimberly R. Coenen, Michael J. Puglisi, Robert S. Lee-Young, Alyssa H. Hasty
Toll-like receptor 4 (TLR4) is a receptor for saturated fatty acids (SFAs), global deficiency of which has been shown to protect against inflammation, insulin resistance and atherosclerotic lesion formation. Because macrophages express Tlr4 and are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92760db18d8551ca38e406e4db3b0947
https://europepmc.org/articles/PMC2615827/
https://europepmc.org/articles/PMC2615827/
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 294(3)
Plasma leptin is often elevated in obese individuals, and previous studies have suggested leptin as a factor that links obesity and atherosclerosis. Because macrophages play a key role in atherogenesis and are responsive to leptin, we hypothesized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e99ae940a77a81eef744fc205b71801
https://pubmed.ncbi.nlm.nih.gov/18182468
https://pubmed.ncbi.nlm.nih.gov/18182468
Publikováno v:
Diabetes. 56(3)
Obesity, hyperlipidemia, and insulin resistance are cardinal features of the metabolic syndrome and individually increase the risk for developing diabetes and cardiovascular disease, a risk that is amplified when they are simultaneously present. It i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bd6ca0b928ab9add4d0533e04290f3
https://pubmed.ncbi.nlm.nih.gov/17327423
https://pubmed.ncbi.nlm.nih.gov/17327423
Publikováno v:
The Journal of nutritional biochemistry. 18(11)
We have reported that obese leptin-deficient mice (ob/ob) lacking the low-density lipoprotein receptor (LDLR(-/-)) develop severe hyperlipidemia and spontaneous atherosclerosis. In the present study, we show that obese leptin receptor-deficient mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c37ff840ff48c86519b6a44103fb43
https://pubmed.ncbi.nlm.nih.gov/17418556
https://pubmed.ncbi.nlm.nih.gov/17418556
Autor:
Alli M. Nuotio-Antar, Viswanathan Saraswathi, Kimberly R. Coenen, Michelle R. Plummer, Alyssa H. Hasty, Marnie L. Gruen
Publikováno v:
Atherosclerosis. 186(1)
Despite a clear association between obesity, insulin resistance and atherosclerosis in humans, to date, no animal models have been described in which insulin resistance is associated with atherosclerotic lesion burden. Using two mouse models of obesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee256b23e81b0373c37774aea450f73
https://pubmed.ncbi.nlm.nih.gov/16102772
https://pubmed.ncbi.nlm.nih.gov/16102772