Výsledky vyhledávání - "Kimberly R Sabsay"

Evolution of transient RNA structure-RNA polymerase interactions in respiratory RNA virus genomes

Autor: Charlotte V Rigby, Kimberly R Sabsay, Karishma Bisht, Dirk Eggink, Hamid Jalal, Aartjan J.W. te Velthuis

Publikováno v: bioRxiv

RNA viruses are important human pathogens that cause seasonal epidemics and occasional pandemics. Examples are influenza A viruses (IAV) and coronaviruses (CoV). When emerging IAV and CoV spill over to humans, they adapt to evade immune responses and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa216488191a223f813d10fa98d2b44
https://europepmc.org/articles/PMC10245964/

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Computational Models for Activated Human MEK1: Identification of Key Active Site Residues and Interactions

Autor: Ashley Ringer McDonald, Leandre M. Ravatt, Rebecca T. Lee, Javin P. Oza, Kimberly R. Sabsay

Publikováno v: Journal of chemical information and modeling. 59(5)

MEK1 is a protein kinase in the MAPK cellular signaling pathway that is notable for its dual specificity and its potential as a drug target for a variety of cancer therapies. While much is known about the key role of MEK1 in signaling events, underst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5420907ae99c857c5eb6faf3c045c02
https://pubmed.ncbi.nlm.nih.gov/30879307