Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kimberly R Drake"'
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9806 (2010)
The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol. Microtubule-associated protein light chain 3 (LC3) was the first protein shown to specifically label autophagosomal membranes in m
Externí odkaz:
https://doaj.org/article/de9385b6ab1d4a589966149b12e1e5b1
Autor:
James R. Goldenring, Lynne A. Lapierre, Anne K. Kenworthy, Nicole A. Ducharme, Kimberly R. Drake
Publikováno v:
Experimental Cell Research. 318:103-113
Recent studies have identified caveolin-1, a protein best known for its functions in caveolae, in apical endocytic recycling compartments in polarized epithelial cells. However, very little is known about the regulation of caveolin-1 in the endocytic
Autor:
Randall K. Holmes, Eli Kern, Michael G. Jobling, David E. Saslowsky, Anne K. Kenworthy, Anne A. Wolf, Wayne I. Lencer, Kimberly R. Drake
Publikováno v:
Infection and Immunity. 76:1476-1484
Cholera toxin (CT) moves from the plasma membrane (PM) of host cells to the endoplasmic reticulum (ER) by binding to the lipid raft ganglioside GM 1 . The homopentomeric B-subunit of the toxin can bind up to five GM 1 molecules at once. Here, we exam
Autor:
Michael W. Davidson, Bing Han, Daniel J.-F. Chinnapen, Nicholas W. Baetz, Anne K. Kenworthy, Charles A. Day, Courtney A. Copeland, Randall K. Holmes, Kimberly R. Drake, Trina A. Schroer, Heidi De Luca, Lewis J. Kraft, Michael G. Jobling, Ajit Tiwari, Wayne I. Lencer
Publikováno v:
Traffic (Copenhagen, Denmark)
How the plasma membrane is bent to accommodate clathrin-independent endocytosis remains uncertain. Recent studies suggest Shiga and cholera toxin induce membrane curvature required for their uptake into clathrin-independent carriers by binding and cr
Autor:
Charles A. Day, Nicholas W. Baetz, Ajit Tiwari, Kimberly R. Drake, Courtney A. Copeland, Lewis J. Kraft, Bing Han, Daniel J. Chinnapen, Michael W. Davidson, Randall K. Holmes, Michael G. Jobling, Trina A. Schroer, Wayne I. Lencer, Anne K. Kenworthy
Publikováno v:
Biophysical Journal. 108(2)
Autor:
M. David Ullman, Tobias Baumgart, Hyejung Park, David E. Saslowsky, Lydia Kaoutzani, Jessica Wagner, Minchul Kang, Anne K. Kenworthy, Eelke Brandsma, Ludovic D'Auria, Daniel J.-F. Chinnapen, Thomas L. Benjamin, Wan-Ting Hsieh, Kimberly R. Drake, Catherine E. Costello, Wayne I. Lencer, Yvonne M. te Welscher, Ramiro Massol
Publikováno v:
Developmental Cell, Vol. 23, no.3, p. 573-86 (2012)
Summary The glycosphingolipid GM1 binds cholera toxin (CT) on host cells and carries it retrograde from the plasma membrane (PM) through endosomes, the trans -Golgi (TGN), and the endoplasmic reticulum (ER) to induce toxicity. To elucidate how a memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eac55f217d66e0851b041b7d0e67c8c
https://hdl.handle.net/2078.1/226093
https://hdl.handle.net/2078.1/226093
Publikováno v:
Biophysical Journal. 98(3)
The B subunit of cholera toxin (CTXB) is generally accepted as a marker of lipid rafts. Compared to other raft markers or lipid-anchored proteins, CTXB exhibits relatively slow diffusion. A variety of mechanisms could potentially account for this slo
Fluorescence recovery after photobleaching (FRAP) using confocal laser scanning microscopes (confocal FRAP) has become a valuable technique for studying the diffusion of biomolecules in cells. However, two-dimensional confocal FRAP sometimes yields r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f802fe30a6a1ed605d9b5faf73405f0
https://europepmc.org/articles/PMC2749741/
https://europepmc.org/articles/PMC2749741/
Autor:
Anne K. Kenworthy, J. Shawn Goodwin, Carl E. Rogers, Mark R. Philips, Kimberly R. Drake, Latasha Wright, Jennifer Lippincott-Schwartz
Publikováno v:
The Journal of Cell Biology
Palmitoylation is postulated to regulate Ras signaling by modulating its intracellular trafficking and membrane microenvironment. The mechanisms by which palmitoylation contributes to these events are poorly understood. Here, we show that dynamic tur
Publikováno v:
Microscopy and Microanalysis. 17:326-327
Extended abstract of a paper presented at Microscopy and Microanalysis 2011 in Nashville, Tennessee, USA, August 7–August 11, 2011.