Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kimberly Phan"'
Autor:
Ophélie d’Udekem d’Acoz, Fong Hue, Tianyi Ye, Louise Wang, Maxime Leroux, Lucila Rajngewerc, Tung Tran, Kimberly Phan, Maria S. Ramirez, Walter Reisner, Marcelo E. Tolmasky, Rodrigo Reyes-Lamothe
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTAminoglycosides are essential components in the available armamentarium to treat bacterial infections. The surge and rapid dissemination of resistance genes strongly reduce their efficiency, compromising public health. Among the multitude of
Externí odkaz:
https://doaj.org/article/210fadee2ade493798bc761ed0b11068
Autor:
Jesus Magallon, Peter Vu, Craig Reeves, Stella Kwan, Kimberly Phan, Crista L. Oakley-Havens, Kenneth Rocha, Veronica Jimenez, María Soledad Ramirez, Marcelo E. Tolmasky
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract Resistance to amikacin in Gram-negatives is usually mediated by the 6'-N-acetyltransferase type Ib [AAC(6')-Ib], which catalyzes the transfer of an acetyl group from acetyl CoA to the 6' position of the antibiotic molecule. A path to continu
Externí odkaz:
https://doaj.org/article/a3118b4688dc433ba0e413c0eb15c5dd
Autor:
Jasmine Martinez, Chelsea Razo-Gutierrez, Casin Le, Robert Courville, Camila Pimentel, Christine Liu, Sammie E. Fung, Marisel R. Tuttobene, Kimberly Phan, Alejandro J. Vila, Parvin Shahrestani, Veronica Jimenez, Marcelo E. Tolmasky, Scott A. Becka, Krisztina M. Papp-Wallace, Robert A. Bonomo, Alfonso Soler-Bistue, Rodrigo Sieira, Maria Soledad Ramirez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract In a recent report by the Centers for Disease Control and Prevention (CDC), multidrug resistant (MDR) Acinetobacter baumannii is a pathogen described as an “urgent threat.” Infection with this bacterium manifests as different diseases su
Externí odkaz:
https://doaj.org/article/e90f21769c5941c48c34928a84a7b5de
Autor:
David Ngo, Angel J. Magaña, Tung Tran, Jan Sklenicka, Kimberly Phan, Brian Eykholt, Verónica Jimenez, María S. Ramirez, Marcelo E. Tolmasky
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 236 (2023)
Plazomicin is a recent U.S. Food and Drug Administration (FDA)-approved semisynthetic aminoglycoside. Its structure consists of a sisomicin scaffold modified by adding a 2(S)-hydroxy aminobutyryl group at the N1 position and a hydroxyethyl substituen
Externí odkaz:
https://doaj.org/article/8f5558aee32c47369259aa92ccc552b2
Autor:
Veronica Batallones, Jennifer Fernandez, Brett Farthing, Jordan Shoemaker, Keizen Li Qian, Kimberly Phan, Eric Fung, Ashley Rivera, Kevin Van, Francesca de la Cruz, Alexandra J. Ferreri, Krystle Burinski, Jackie Zhang, Vicente Lizarraga, Kevin Doan, Kenneth Rocha, German Traglia, Maria S. Ramirez, Marcelo E. Tolmasky
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Vibrio anguillarum 531A, isolated from a diseased fish in the Atlantic Ocean, is a mixture composed of about 95 and 5% of highly pigmented cells (strain 531Ad) and cells with normal levels of pigmentation (strain 531Ac), respectively. Analys
Externí odkaz:
https://doaj.org/article/3335bd8de0424e7a8b235ad9d0c0b6f0
Autor:
Kenneth Rocha, Jesus Magallon, Craig Reeves, Kimberly Phan, Peter Vu, Crista L. Oakley-Havens, Stella Kwan, Maria Soledad Ramirez, Travis LaVoi, Haley Donow, Prem Chapagain, Radleigh Santos, Clemencia Pinilla, Marc A. Giulianotti, Marcelo E. Tolmasky
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1218 (2021)
The aminoglycoside 6′-N-acetyltransferase type Ib (AAC(6′)-Ib) is a common cause of resistance to amikacin and other aminoglycosides in Gram-negatives. Utilization of mixture-based combinatorial libraries and application of the positional scannin
Externí odkaz:
https://doaj.org/article/1a871c56781944109a6547b83c05aebb
Autor:
Craig M. Reeves, Jesus Magallon, Kenneth Rocha, Tung Tran, Kimberly Phan, Peter Vu, Yang Yi, Crista L. Oakley-Havens, José Cedano, Verónica Jimenez, Maria S. Ramirez, Marcelo E. Tolmasky
Publikováno v:
Antibiotics, Vol 10, Iss 1, p 29 (2020)
Clinical resistance to amikacin and other aminoglycosides is usually due to the enzymatic acetylation of the antimicrobial molecule. A ubiquitous resistance enzyme among Gram-negatives is the aminoglycoside 6′-N-acetyltransferase type Ib [AAC(6′)
Externí odkaz:
https://doaj.org/article/b3be84ac11914635ae62a0818d0f337e
Autor:
Camila Pimentel, Robert A. Bonomo, Alejandro J. Vila, Robert Courville, Jasmine Martinez, Rodrigo Sieira, Sammie Fung, Veronica Jimenez, Maria Soledad Ramirez, Parvin Shahrestani, Christine Liu, Marcelo E. Tolmasky, Kimberly Phan, Marisel R. Tuttobene, Casin Le, Chelsea Razo-Gutierrez, Alfonso Soler-Bistué, Scott A. Becka, Krisztina M. Papp-Wallace
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
In a recent report by the Centers for Disease Control and Prevention (CDC), multidrug resistant (MDR) Acinetobacter baumannii is a pathogen described as an “urgent threat.” Infection with this bacterium manifests as different diseases such as com
Autor:
Crista L. Oakley-Havens, Craig Reeves, Maria Soledad Ramirez, Stella Kwan, Peter Vu, Jesus Magallon, Veronica Jimenez, Kenneth Rocha, Marcelo E. Tolmasky, Kimberly Phan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Resistance to amikacin in Gram-negatives is usually mediated by the 6'-N-acetyltransferase type Ib [AAC(6')-Ib], which catalyzes the transfer of an acetyl group from acetyl CoA to the 6' position of the antibiotic molecule. A path to continue the eff
Autor:
Crista L. Oakley-Havens, Haley M. Donow, Radleigh G. Santos, Craig Reeves, Kimberly Phan, Marcelo E. Tolmasky, Maria Soledad Ramirez, Kenneth Rocha, Clemencia Pinilla, Marc A. Giulianotti, Travis LaVoi, Jesus Magallon, Stella Kwan, Peter Vu, Prem P. Chapagain
Publikováno v:
Biomedicines, Vol 9, Iss 1218, p 1218 (2021)
Biomedicines
Volume 9
Issue 9
Biomedicines
Volume 9
Issue 9
The aminoglycoside 6′-N-acetyltransferase type Ib (AAC(6′)-Ib) is a common cause of resistance to amikacin and other aminoglycosides in Gram-negatives. Utilization of mixture-based combinatorial libraries and application of the positional scannin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda1658eaf3f710eca248d146f6090b1