Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kimberly N. Weiderhold"'
Autor:
Kimberly N Weiderhold, Maria Fadri-Moskwik, Jing Pan, Michiya Nishino, Carol Chuang, Arpaporn Deeraksa, Sue-Hwa Lin, Li-Yuan Yu-Lee
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153455 (2016)
Nuclear distribution protein C (NudC) is a mitotic regulator that plays a role in cytokinesis. However, how NudC is regulated during cytokinesis remains unclear. Here, we show that NudC is phosphorylated by Aurora B, a kinase critical for cell abscis
Externí odkaz:
https://doaj.org/article/ad0f0c976dce462aaea219b2306c5a0c
Autor:
Carol Chuang, Jing Pan, Kimberly N. Weiderhold, Arpaporn Deeraksa, Li Yuan Yu-Lee, Maria Fadri-Moskwik, Sue Hwa Lin, Michiya Nishino
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153455 (2016)
PLoS ONE
PLoS ONE
Nuclear distribution protein C (NudC) is a mitotic regulator that plays a role in cytokinesis. However, how NudC is regulated during cytokinesis remains unclear. Here, we show that NudC is phosphorylated by Aurora B, a kinase critical for cell abscis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130820ee5ae2c7cadea4e392256552db
http://europepmc.org/articles/PMC4830538?pdf=render
http://europepmc.org/articles/PMC4830538?pdf=render
Autor:
Edith J. Banner, Susan L. Mooberry, Jonathan E. Hempel, John T. Gupton, Milton L. Brown, Kimberly N. Weiderhold, Ernest Hamel, Anastasia Kharlamova, Sivanesan Dakshanamurthy
Publikováno v:
Molecular Pharmacology. 72:132-140
We studied the mechanism of action of 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester (JG-03-14) and found that it is a potent microtubule depolymerizer. JG-03-14 caused a dose-dependent loss of cellular microtubules, for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d26c0bafcd3c0d34a3c884f9c9dc137
https://doi.org/10.1124/mol.107.034876
https://doi.org/10.1124/mol.107.034876
Autor:
Ernest Hamel, Susan L. Mooberry, Lisa Polin, Deborah A. Randall-Hlubek, Kimberly N. Weiderhold
Publikováno v:
International Journal of Cancer. 118:1032-1040
During the course of a mechanism-based screening program aimed at identifying new antimitotic agents, a novel microtubule depolymerizing piperazine derivative, 1-(5-chloro-2-methoxybenzoyl)-4-(3-chlorophenyl) piperazine, was identified. The compound,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789c7c69d763c02ac2fdfe7aabed0963
https://doi.org/10.1002/ijc.21424
https://doi.org/10.1002/ijc.21424
Autor:
Jing Pan, Carol Chuang, Maria Fadri-Moskwik, Sue Hwa Lin, Arpaporn Deeraksa, Li Yuan Yu-Lee, Kimberly N. Weiderhold
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(10)
Protein acetylation has been implicated in playing an important role during mitotic progression. Aurora B kinase is known to play a critical role in mitosis. However, whether Aurora B is regulated by acetylation is not known. Using IP with an anti-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaf306488591473fc8352bb6c3beb62
https://pubmed.ncbi.nlm.nih.gov/22751009
https://pubmed.ncbi.nlm.nih.gov/22751009