Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kimberly Malesky"'
Autor:
Guangliang Wang, Guoqiang Zhang, Zhuyun Li, Caroline H. Fawcett, Matthew Coble, Maria X. Sosa, Tingwei Tsai, Kimberly Malesky, Stefan J. Thibodeaux, Peixin Zhu, David J. Glass, Mark C. Fishman
Publikováno v:
iScience, Vol 17, Iss , Pp 325-333 (2019)
Summary: Dopamine transporter (SLC6A3) deficiency causes infantile Parkinson disease, for which there is no effective therapy. We have explored the effects of genetically deleting SLC6A3 in zebrafish. Unlike the wild-type, slc6a3−/− fish hover ne
Externí odkaz:
https://doaj.org/article/d16c909bf955415fad825198f1e76974
Autor:
Kimberly Malesky, Donald C. Lo, Guizhi Yang, Alice Loo, Hui Gao, Joshua M. Korn, Raymond Pagliarini, Brent R. Stockwell, Fallon Lin, Tom Mikkelsen, Eduard Reznik, Ana C. deCarvalho, Ling F. Ye
Publikováno v:
Oncotarget
There is a compelling need for new therapeutic strategies for glioblastoma multiforme (GBM). Preclinical target and therapeutic discovery for GBMs is primarily conducted using cell lines grown in serum-containing media, such as U-87 MG, which do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e622bca7b5e1967914a420da39d39c8e
https://doi.org/10.18632/oncotarget.27457
https://doi.org/10.18632/oncotarget.27457
Autor:
Stefan J. Thibodeaux, Mark C. Fishman, Maria X. Sosa, Guoqiang Zhang, Peixin Zhu, Kimberly Malesky, Guangliang Wang, Caroline H. Fawcett, Zhuyun Li, Matthew Coble, David J. Glass, Tingwei Tsai
Publikováno v:
iScience
iScience, Vol 17, Iss, Pp 325-333 (2019)
iScience, Vol 17, Iss, Pp 325-333 (2019)
Summary Dopamine transporter (SLC6A3) deficiency causes infantile Parkinson disease, for which there is no effective therapy. We have explored the effects of genetically deleting SLC6A3 in zebrafish. Unlike the wild-type, slc6a3−/− fish hover nea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a957db163fbae2d390051508013ca9
http://europepmc.org/articles/PMC6642228
http://europepmc.org/articles/PMC6642228
Autor:
Jan Marik, Janet Tien, Simon Williams, Elaine Mai, Samir Kharbanda, Jennifer A. Lacap, Kimberly Malesky, Gail Lewis Phillips, Heidi S. Phillips, Merry C. Nishimura
Publikováno v:
Breast Cancer Research and Treatment
Purpose The extent to which efficacy of the HER2 antibody Trastuzumab in brain metastases is limited by access of antibody to brain lesions remains a question of significant clinical importance. We investigated the uptake and distribution of trastuzu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd2404797f7b3ffbb955f69b3e9bfa9
http://europepmc.org/articles/PMC5495871
http://europepmc.org/articles/PMC5495871
Autor:
Joyce Mordenti, Daniel A. Dickman, Walter Yu, David Sperandio, Kimberly Malesky, Tania Mahajan, Emma J. Shelton, Dener Jeffrey M, Zhiwei Tong, Colin O’Brian, Robert Yee, Paul G. Grothaus, Yun Ling, Chris Havel, Liang Liu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:4053-4058
The metabolites of the tryptase inhibitor CRA-9249 were identified after exposure to liver microsomes. CRA-9249 was found to be degraded rapidly in liver microsomes from rabbit, dog, cynomolgus monkey, and human, and less rapidly in microsomes from r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88720966e50f9e54742b47bf1ab6cfe5
https://doi.org/10.1016/j.bmcl.2006.05.003
https://doi.org/10.1016/j.bmcl.2006.05.003