Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Kimberly M. Brothers"'
Autor:
Jonathan B. Mandell, Charles Gish, Alex J. Cappellini, Dana M. Parker, Kimberly M. Brothers, Dongzhu Ma, Kenneth L. Urish
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Staphylococcus aureus infections are hard to treat due to the emergence of antibiotic resistant strains, as well as their ability to form biofilms. The MazEF toxin–antitoxin system is thought play a role in bacterial biofilm phenotype as w
Externí odkaz:
https://doaj.org/article/40e127184b1d417aa8538601d934000a
Autor:
Kimberly M. Brothers, Dana M. Parker, Masashi Taguchi, Dongzhu Ma, Jonathan B. Mandell, Lance L. Thurlow, Venkata C. Byrapogu, Kenneth L. Urish
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Antibiotic stewardship is viewed as having great public health benefit with limited direct benefit to the patient at the time of administration. The objective of our study was to determine if inappropriate administration of antibiotics could
Externí odkaz:
https://doaj.org/article/296df98e54804bc5a6a6e56ead6da5b4
Autor:
Dana M. Parker, John A. Koch, Charles G. Gish, Kimberly M. Brothers, William Li, Jessica Gilbertie, Sarah E. Rowe, Brian P. Conlon, Venkata K. C. Byrapogu, Kenneth L. Urish
Publikováno v:
Life, Vol 13, Iss 6, p 1230 (2023)
Hydrogen peroxide, povidone-iodine, and chlorhexidine are antiseptics that are commonly added to irrigants to either prevent or treat infection. There are little clinical data available that demonstrate efficacy of adding antiseptics to irrigants in
Externí odkaz:
https://doaj.org/article/c60d198aa2e14f7d93b16ea167a96030
Publikováno v:
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The cellular process of autophagy is essential for maintaining the health of ocular tissue. Dysregulation of autophagy is associated with several ocular diseases including keratoconus and macular degeneration. It is known that aut
Externí odkaz:
https://doaj.org/article/397e994854b34052a1982b97e387828f
Autor:
David Huang, Dana M. Parker, Jonathan B. Mandell, Kimberly M. Brothers, Charles G. Gish, John A. Koch, Nicholas Pachuda, Despina Dobbins, Jonathan Steckbeck, Kenneth L. Urish
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT PLG0206 is an engineered antimicrobial peptide that has completed phase 1 clinical studies. A prospective study was completed on explanted implants from chronic periprosthetic joint infections (n = 17). At a concentration of 1 mg/mL for 15 m
Externí odkaz:
https://doaj.org/article/b95bb937d31d4a04b3c64fc06450c556
Publikováno v:
Antibiotics, Vol 10, Iss 7, p 770 (2021)
Relatively little is known about how the corneal epithelium responds to vision-threatening bacteria from the Enterobacterales order. This study investigates the impact of Serratia marcescens on corneal epithelial cell host responses. We also investig
Externí odkaz:
https://doaj.org/article/fa6d1cd9b0814332a8623324afe13c54
Autor:
John A. Koch, Taylor M. Pust, Alex J. Cappellini, Jonathan B. Mandell, Dongzhu Ma, Neel B. Shah, Kimberly M. Brothers, Kenneth L. Urish
Publikováno v:
Life, Vol 10, Iss 11, p 253 (2020)
Both Staphylococcus aureus and Staphylococcus epidermidis are commonly associated with periprosthetic joint infections (PJIs). The treatment of PJI can be challenging because biofilms are assumed to have an increased intolerance to antibiotics. This
Externí odkaz:
https://doaj.org/article/b2e467e46f584ad1ae6677c2523b5a6e
Autor:
Irena Antic, Kimberly M. Brothers, Maureen Stolzer, Han Lai, Evan Powell, Rory Eutsey, Rolando A. Cuevas, Xinyu Miao, Regis P. Kowalski, Robert M. Q. Shanks, Dannie Durand, N. Luisa Hiller
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Streptococcus pneumoniae (pneumococcus) displays broad tissue tropism and infects multiple body sites in the human host. However, infections of the conjunctiva are limited to strains within a distinct phyletic group with multilocus sequence
Externí odkaz:
https://doaj.org/article/01beb50ab4f44666ad77049bc03a0bf2
Autor:
Dana M. Parker, John A. Koch, Charles G. Gish, Kimberly M. Brothers, William Li, Jessica Gilbertie, Sarah E. Rowe, Brian P. Conlon, Venkata K. C. Byrapogu, Kenneth L. Urish
Hydrogen peroxide, povidone-iodine, and chlorhexidine are antiseptics that are commonly added to irrigants to either prevent or treat infection. There are little clinical data available that demonstrate efficacy of adding antiseptics to irrigants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0f39e8d74122f4a74a4205613e58a5
Autor:
Nicholas A. Stella, Eric G. Romanowski, Kimberly M. Brothers, Rachel C. Calvario, Robert M. Q. Shanks
Publikováno v:
Infect Immun
Bacterial stress response signaling systems, like the Rcs system are triggered by membrane and cell wall damaging compounds, including antibiotics and immune system factors. These regulatory systems help bacteria survive envelope stress by altering t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1906d9f4403c13c1168e2c0c62430d32
https://europepmc.org/articles/PMC9671016/
https://europepmc.org/articles/PMC9671016/