Výsledky vyhledávání - "Kimberly M Zorn"

Akademický článek

Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters.

Autor: Samit Ganguly, David Finkelstein, Timothy I Shaw, Ryan D Michalek, Kimberly M Zorn, Sean Ekins, Kazuto Yasuda, Yu Fukuda, John D Schuetz, Kamalika Mukherjee, Erin G Schuetz

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0253852 (2021)

Abcg2/Bcrp and Abcb1a/Pgp are xenobiotic efflux transporters limiting substrate permeability in the gastrointestinal system and brain, and increasing renal and hepatic drug clearance. The systemic impact of Bcrp and Pgp ablation on metabolic homeosta

Externí odkaz: https://doaj.org/article/b18f9e558107487fa2603259aa77bcbd

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Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters

Autor: Ryan D. Michalek, Samit Ganguly, David Finkelstein, Yu Fukuda, Sean Ekins, Kimberly M. Zorn, John D. Schuetz, Timothy I. Shaw, Kamalika Mukherjee, Erin G. Schuetz, Kazuto Yasuda

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0253852 (2021)
PLoS ONE

Abcg2/Bcrp and Abcb1a/Pgp are xenobiotic efflux transporters limiting substrate permeability in the gastrointestinal system and brain, and increasing renal and hepatic drug clearance. The systemic impact of Bcrp and Pgp ablation on metabolic homeosta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f856f32db4e01c0fc7bd5b0397670eb
https://doi.org/10.1371/journal.pone.0253852

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Using machine learning to identify chaperones for sialidosis

Autor: Nancy C. Baker, Sean Ekins, Daniel H. Foil, Jennifer J. Klein, Ana Puhl Rubio, Kimberly M. Zorn

Publikováno v: Molecular Genetics and Metabolism. 129:S90-S91

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6252856f952f1cf350136d884868ce66
https://doi.org/10.1016/j.ymgme.2019.11.226

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Akademický článek

Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters.

Autor: Ganguly, Samit¹ (AUTHOR), Finkelstein, David² (AUTHOR), Shaw, Timothy I.² (AUTHOR), Michalek, Ryan D.³ (AUTHOR), Zorn, Kimberly M.⁴ (AUTHOR), Ekins, Sean⁴ (AUTHOR), Yasuda, Kazuto⁵ (AUTHOR), Fukuda, Yu⁵ (AUTHOR), Schuetz, John D.⁵ (AUTHOR), Mukherjee, Kamalika⁵ (AUTHOR), Schuetz, Erin G.⁵ (AUTHOR) erin.schuetz@stjude.org

Publikováno v: PLoS ONE. 7/13/2021, Vol. 16 Issue 7, p1-33. 33p.

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