Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kimberly M Cirelli"'
Autor:
Kenneth Olivier, Jin He, Ribhu Nayar, Sonal Jangalwe, Qikai Xu, Yifan Wang, Amy Virbasius, Alexander Cristofaro, Gavin MacBeath, Kenneth L Jahan, Nicolas Gaspar, Kimberly M Cirelli, Shazad A Khokhar, Shubhangi Kamalia, Sveta Padmanabhan, Badr Kiaf, Victor Ospina, Alok Das Mahopatra, Tary Traore, Antoine J Boudot, Livio Dukaj, Ryan E Kritzer, Chandan K Pavuluri, Daniel C Pollacksmith, Hannah Bader, Nivya Sharma, Debanjan Goswamy, Vivin Karthik, Elisaveta Todorova, Tyler M Sinacola, Savannah G Szemethy, Kyra N Sur, Vandana Keskar, Chris Malcuit, Danielle Ramsdell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9fa2478263d74cb48c95f48851e3d7cf
Autor:
Jin He, Ribhu Nayar, Mollie Jurewicz, Qikai Xu, Yifan Wang, Alexander Cristofaro, Nancy Nabilsi, Gavin MacBeath, Jenny Tadros, Akshat Sharma, Kenneth L Jahan, Nicolas Gaspar, Kimberly M Cirelli, Teagan Parsons, Shazad A Khokhar, Shubhangi Kamalia, Sveta Padmanabhan, Badr Kiaf, Victor Ospina, Alok Das Mahopatra, Tary Traore, Antoine J Boudot, Livio Dukaj, Ryan E Kritzer, Chandan K Pavuluri, Emily Miga, Cagan Gurer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/28b59cafa8284237ac2d41f5616205a8
Autor:
Samantha Reiss, Amy E Baxter, Kimberly M Cirelli, Jennifer M Dan, Antigoni Morou, Audrey Daigneault, Nathalie Brassard, Guido Silvestri, Jean-Pierre Routy, Colin Havenar-Daughton, Shane Crotty, Daniel E Kaufmann
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186998 (2017)
The identification and study of antigen-specific CD4 T cells, both in peripheral blood and in tissues, is key for a broad range of immunological research, including vaccine responses and infectious diseases. Detection of these cells is hampered by bo
Externí odkaz:
https://doaj.org/article/c8fcca0f39e748e4b4f7d2b553b8dd01
Autor:
Kimberly M Cirelli, Gezahegn Gorfu, Musa A Hassan, Morton Printz, Devorah Crown, Stephen H Leppla, Michael E Grigg, Jeroen P J Saeij, Mahtab Moayeri
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003927 (2014)
Toxoplasma gondii is an intracellular parasite that infects a wide range of warm-blooded species. Rats vary in their susceptibility to this parasite. The Toxo1 locus conferring Toxoplasma resistance in rats was previously mapped to a region of chromo
Externí odkaz:
https://doaj.org/article/08ffeadd52ba4b23a88d6edb3374c793
Autor:
Jeong Hyun Lee, Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T. Richey, Jonathan L. Torres, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M. Cirelli, Amitinder Kaur, Carolina Allers, Marissa Fahlberg, Brooke F. Grasperge, Jason P. Dufour, Faith Schiro, Pyone P. Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G. Carnathan, Guido Silvestri, Xiaoying Shen, David C. Montefiori, Ronald S. Veazey, Andrew B. Ward, Lars Hangartner, Dennis R. Burton, Darrell J. Irvine, William R. Schief, Shane Crotty
Publikováno v:
Nature. 609:998-1004
Germinal centres are the engines of antibody evolution. Here, using human immunodeficiency virus (HIV) Env protein immunogen priming in rhesus monkeys followed by a long period without further immunization, we demonstrate germinal centre B (B
Autor:
Jeong Hyun Lee, Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T. Richey, Jonathan L. Torres, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M. Cirelli, Amitinder Kaur, Carolina Allers, Marissa Fahlberg, Brooke F. Grasperge, Jason P. Dufour, Faith Schiro, Pyone P. Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G. Carnathan, Guido Silvestri, Xiaoying Shen, David C. Montefiori, Ronald S. Veazey, Andrew B. Ward, Lars Hangartner, Dennis R. Burton, Darrell J. Irvine, William R. Schief, Shane Crotty
Publikováno v:
Nature. 614:E43-E43
Autor:
Aleksandar Antanasijevic, Charles A. Bowman, Robert N. Kirchdoerfer, Christopher A. Cottrell, Gabriel Ozorowski, Amit A. Upadhyay, Kimberly M. Cirelli, Diane G. Carnathan, Chiamaka A. Enemuo, Leigh M. Sewall, Bartek Nogal, Fangzhu Zhao, Bettina Groschel, William R. Schief, Devin Sok, Guido Silvestri, Shane Crotty, Steven E. Bosinger, Andrew B. Ward
Publikováno v:
Science Advances
One of the rate-limiting steps in analyzing immune responses to vaccines or infections is the isolation and characterization of monoclonal antibodies. Here, we present a hybrid structural and bioinformatic approach to directly assign the heavy and li
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
Autor:
Wuhbet Abraham, Erik Georgeson, Kangsan Roh, Jason Y. Chang, Shuhao Xiao, Daniel Lingwood, Brittany L. Hartwell, Ivy Phung, Bettina Groschel, Diane G Carnathan, Ayush Thomas, Kimberly M. Cirelli, Darrell J. Irvine, Murillo Silva, Li Zhongming, Galit Alter, Guido Silvestri, Jan Willem Maurits van Wijnbergen, Jinal Bhiman, Caitlyn Linde, Yu Kato, Timothy P. Padera, Raiza Bastidas, Hannah C. Watkins, William R. Schief, Sonya Haupt, Swati Kataria, Julia Bals, Dennis R. Burton, Ruth M. Ruprecht, Shane Crotty, Nicole Phelps, Kristen A Rodrigues, Mariane B. Melo, Angela M. Belcher, Brian L. Freeman, Na Li, Benjamin J. Cossette, Aereas Aung, Nathaniel I. Bloom, Chiamaka A. Enemuo
Publikováno v:
Sci Immunol
Saponins are potent and safe vaccine adjuvants, but their mechanisms of action remain incompletely understood. Here, we explored the properties of several saponin formulations, including immunostimulatory complexes (ISCOMs) formed by the self-assembl
Autor:
Jeong Hyun Lee, Henry Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T. Richey, Jonathan L. Torres, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M. Cirelli, Amitinder Kaur, Carolina Allers-Hernandez, Marissa Fahlberg, Brooke F. Grasperge, Jason P. Dufour, Faith Schiro, Pyone P. Aye, Diane G. Carnathan, Guido Silvestri, Xiaoying Shen, David C. Montefiori, Ronald S. Veazey, Andrew B. Ward, Lars Hangartner, Dennis R. Burton, Darrell J. Irvine, William R. Schief, Shane Crotty
SummaryGerminal centers (GCs) are the engines of antibody evolution. Using HIV Env protein immunogen priming in rhesus monkeys (RM) followed by a long period without further immunization, we demonstrate GC B cells (BGC) lasted at least 6 months (29 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a51bf6131d52a6dd242f16566c8aab62
https://doi.org/10.1101/2021.12.20.473537
https://doi.org/10.1101/2021.12.20.473537
Autor:
Diane G. Carnathan, Christopher A. Cottrell, Shane Crotty, Aleksandar Antanasijevic, William R. Schief, George Ueda, David Baker, Jeffrey Copps, Chiamaka A. Enemuo, Kimberly M. Cirelli, Talar Tokatlian, Sergey Menis, Jacob T. Martin, Torben Schiffner, Yury Choe, Neil P. King, Benjamin J. Cossette, Federico Viviano, Guido Silvestri, Etse H. Gebru, Darrell J. Irvine, Andrew B. Ward
Following immunization, high affinity antibody responses develop within germinal centers (GCs), specialized sites within follicles of the lymph node (LN) where B cells proliferate and undergo somatic hypermutation. Antigen availability within GCs is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6db4cb6c23f08bb7cc5dde040647509
https://doi.org/10.1101/2020.02.19.956482
https://doi.org/10.1101/2020.02.19.956482