Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Kimberly M Brothers"'
Autor:
David B Huang, Kimberly M Brothers, Jonathan B Mandell, Masashi Taguchi, Peter G Alexander, Dana M Parker, Dean Shinabarger, Chris Pillar, Ian Morrissey, Stephen Hawser, Parviz Ghahramani, Despina Dobbins, Nicholas Pachuda, Ronald Montelaro, Jonathan D Steckbeck, Kenneth L Urish
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274815 (2022)
The absence of novel antibiotics for drug-resistant and biofilm-associated infections is a global public health crisis. Antimicrobial peptides explored to address this need have encountered significant development challenges associated with size, tox
Externí odkaz:
https://doaj.org/article/59eaa2222fdc466fabfaa701ec609c4a
Autor:
Kimberly M Brothers, Jake D Callaghan, Nicholas A Stella, Julianna M Bachinsky, Mohammed AlHigaylan, Kara L Lehner, Jonathan M Franks, Kira L Lathrop, Elliot Collins, Deanna M Schmitt, Joseph Horzempa, Robert M Q Shanks
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007825 (2019)
Medical devices, such as contact lenses, bring bacteria in direct contact with human cells. Consequences of these host-pathogen interactions include the alteration of mammalian cell surface architecture and induction of cellular death that renders ti
Externí odkaz:
https://doaj.org/article/1729cb2794644a3098fcc774c40683f1
Autor:
Jonathan B. Mandell, Charles Gish, Alex J. Cappellini, Dana M. Parker, Kimberly M. Brothers, Dongzhu Ma, Kenneth L. Urish
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Staphylococcus aureus infections are hard to treat due to the emergence of antibiotic resistant strains, as well as their ability to form biofilms. The MazEF toxin–antitoxin system is thought play a role in bacterial biofilm phenotype as w
Externí odkaz:
https://doaj.org/article/40e127184b1d417aa8538601d934000a
Autor:
Emily M Mallick, Audrey C Bergeron, Stephen K Jones, Zachary R Newman, Kimberly M Brothers, Robbert eCreton, Robert T. Wheeler, Richard J Bennett
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Phenotypic diversity is critical to the lifestyles of many microbial species, enabling rapid responses to changes in environmental conditions. In the human fungal pathogen Candida albicans, cells exhibit heritable switching between two phenotypic sta
Externí odkaz:
https://doaj.org/article/14332ab70c9b48a98e0542f22658d09c
Autor:
Robert M Q Shanks, Roni M Lahr, Nicholas A Stella, Kristin E Arena, Kimberly M Brothers, Daniel H Kwak, Xinyu Liu, Eric J Kalivoda
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57634 (2013)
Swarming motility and hemolysis are virulence-associated determinants for a wide array of pathogenic bacteria. The broad host-range opportunistic pathogen Serratia marcescens produces serratamolide, a small cyclic amino-lipid, that promotes swarming
Externí odkaz:
https://doaj.org/article/bc2e78af040e482998ea2fa27395c56e
Autor:
Kimberly M Brothers, Remi L Gratacap, Sarah E Barker, Zachary R Newman, Ashley Norum, Robert T Wheeler
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003634 (2013)
Candida albicans is a human commensal and clinically important fungal pathogen that grows as both yeast and hyphal forms during human, mouse and zebrafish infection. Reactive oxygen species (ROS) produced by NADPH oxidases play diverse roles in immun
Externí odkaz:
https://doaj.org/article/a5d416c5839646ebad306da0c8799006
Autor:
Eric J Kalivoda, Kimberly M Brothers, Nicholas A Stella, Matthew J Schmitt, Robert M Q Shanks
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e71267 (2013)
Biofilm-related infections are a major contributor to human disease, and the capacity for surface attachment and biofilm formation are key attributes for the pathogenesis of microbes. Serratia marcescens type I fimbriae-dependent biofilms are coordin
Externí odkaz:
https://doaj.org/article/c294e53122824cc9b44dcc8ccf052304
Autor:
Robert M Q Shanks, Viral R Davra, Eric G Romanowski, Kimberly M Brothers, Nicholas A Stella, Dipti Godboley, Daniel E Kadouri
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66723 (2013)
Ocular infections are a leading cause of vision loss. It has been previously suggested that predatory prokaryotes might be used as live antibiotics to control infections. In this study, Pseudomonas aeruginosa and Serratia marcescens ocular isolates w
Externí odkaz:
https://doaj.org/article/bcaa2faf6da648bcae075153d8055216
Autor:
Kimberly M. Brothers, Dana M. Parker, Masashi Taguchi, Dongzhu Ma, Jonathan B. Mandell, Lance L. Thurlow, Venkata C. Byrapogu, Kenneth L. Urish
Publikováno v:
Scientific Reports. 13
Antibiotic stewardship is viewed as having great public health benefit with limited direct benefit to the patient at the time of administration. The objective of our study was to determine if inappropriate administration of antibiotics could create c
Autor:
Dana M. Parker, John A. Koch, Charles G. Gish, Kimberly M. Brothers, William Li, Jessica Gilbertie, Sarah E. Rowe, Brian P. Conlon, Venkata K. C. Byrapogu, Kenneth L. Urish
Hydrogen peroxide, povidone-iodine, and chlorhexidine are antiseptics that are commonly added to irrigants to either prevent or treat infection. There are little clinical data available that demonstrate efficacy of adding antiseptics to irrigants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0f39e8d74122f4a74a4205613e58a5