Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kimberly L. Weirich"'
Publikováno v:
Physical Review Research, Vol 3, Iss 4, p 043061 (2021)
Active forces drive critical biological processes such as spontaneous organization and shape change during cell division. Here, we present a minimal hydrodynamic model leading to a unified description of self-organization and division in nematic drop
Externí odkaz:
https://doaj.org/article/9d8d5b08852942b784b2abe2afabedf2
Autor:
Monika Scholz, Stanislav Burov, Kimberly L. Weirich, Björn J. Scholz, S. M. Ali Tabei, Margaret L. Gardel, Aaron R. Dinner
Publikováno v:
Physical Review X, Vol 6, Iss 1, p 011037 (2016)
Power-law dwell times have been observed for molecular motors in living cells, but the origins of these trapped states are not known. We introduce a minimal model of motors moving on a two-dimensional network of filaments, and simulations of its dyna
Externí odkaz:
https://doaj.org/article/97834781e3d24a269ce860cc65bb3d4d
Publikováno v:
Biophys J
The actin cytoskeleton is a soft, structural material that underlies biological processes such as cell division, motility, and cargo transport. The cross-linked actin filaments self-organize into a myriad of architectures, from disordered meshworks t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47f493794b833bac9145b00e7ee1320
https://doi.org/10.1016/j.bpj.2021.03.026
https://doi.org/10.1016/j.bpj.2021.03.026
Publikováno v:
Soft Matter. 16:2135-2140
The interaction of motor proteins with intracellular filaments is required for transport processes and force generation in cells. Within a cell, crosslinking proteins organize cytoskeletal filaments both temporally and spatially to create dynamic, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5c620541f39bc1fafcad3271e8c91c
https://doi.org/10.1039/c9sm01904a
https://doi.org/10.1039/c9sm01904a
Autor:
Thomas A. Witten, Margaret L. Gardel, Kimberly L. Weirich, Kinjal Dasbiswas, Suriyanarayanan Vaikuntanathan
Publikováno v:
Proceedings of the National Academy of Sciences. 116:11125-11130
The cytoskeleton is a collection of protein assemblies that dynamically impose spatial structure in cells and coordinate processes such as cell division and mechanical regulation. Biopolymer filaments, cross-linking proteins, and enzymatically active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78819d1e674e59fc3ad40638ecc9246a
https://doi.org/10.1073/pnas.1814854116
https://doi.org/10.1073/pnas.1814854116
Publikováno v:
Physical Review Research
Physical Review Research, 2021, 3 (4), pp.043061. ⟨10.1103/PhysRevResearch.3.043061⟩
Physical Review Research, 2021, 3 (4), pp.043061. ⟨10.1103/PhysRevResearch.3.043061⟩
Active forces occurring within cells can drive crucial biological processes that involve spontaneous organization and shape change, such as cell division. Motivated by recent in vitro experiments of nematic droplets of cytoskeletal filaments and moto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38922af2619a34502c8cd57337a624f
The actin cytoskeleton is a soft, structural material that underlies biological processes such as cell division, motility, and cargo transport. The cross-linked actin filaments self-organize into a myriad of architectures, from disordered meshworks t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::439197b7eefdb5e00a76782c8f890b95
https://doi.org/10.1101/2020.07.17.207415
https://doi.org/10.1101/2020.07.17.207415
Autor:
Kinjal Dasbiswas, Danielle R. Scheff, Kimberly L. Weirich, Suriyanarayanan Vaikuntanathan, Avinash Patel, Margaret L. Gardel
Publikováno v:
Soft matter. 16(24)
Macromolecules can phase separate to form liquid condensates, which are emerging as critical compartments in fields as diverse as intracellular organization and soft materials design. A myriad of macromolecules, including the protein FUS, form conden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aa7d77af3b90f7758541ab59d63555
https://pubmed.ncbi.nlm.nih.gov/32519715
https://pubmed.ncbi.nlm.nih.gov/32519715
Autor:
Danielle R. Scheff, Avinash Patel, Margaret L. Gardel, Kimberly L. Weirich, Kinjal Dasbiswas, Suriyanarayanan Vaikuntanathan
Publikováno v:
Soft matter, vol 16, iss 24
Macromolecules can phase separate to form liquid condensates, which are emerging as critical compartments in fields as diverse as intracellular organization and soft materials design. A myriad of macromolecules, including the protein FUS, form conden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4055728d865eaaaa502c80145fab1cf
Autor:
Kimberly L. Weirich, Kinjal Dasbiswas, Thomas A. Witten, Eli Alster, Margaret L. Gardel, Nicholas B. Ludwig, Suriyanarayanan Vaikuntanathan
Publikováno v:
The Journal of chemical physics, vol 152, iss 8
Recent experiments have shown how nematically-ordered tactoid shaped actin droplets can be reorganized and divided by the action of myosin molecular motors. In this paper, we consider how similar morphological changes can potentially be achieved unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073b57355feae80feb975310ce5ac9ba
https://doi.org/10.1063/1.5141997
https://doi.org/10.1063/1.5141997