Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kimberly L. Dodge-Kafka"'
Publikováno v:
Journal of Molecular and Cellular Cardiology. 172:26-40
The pleiotropic Ca
Autor:
Kenneth A. Ohgi, Y. Joseph Woo, Yang Li, Qian Yu, Hrishikesh Thakur, Xiaofeng Li, Yuliang Tan, Michael D. Kritzer, Catherine L. Passariello, Craig A. Emter, Eliana C. Martinez, Michael S. Kapiloff, Michael G. Rosenfeld, Kimberly L. Dodge-Kafka, Jr. John W. MacArthur, Xueyi Li, Jinliang Li, Jan R. Ivey
Publikováno v:
Circulation
Background: Concentric and eccentric cardiac hypertrophy are associated with pressure and volume overload, respectively, in cardiovascular disease both conferring an increased risk of heart failure. These contrasting forms of hypertrophy are characte
Autor:
Thomas R Shannon, Dan J Bare, Sabine Van Dijk, Shayan Raofi, Tiffany N-M Huynh, Yang K Xiang, Julie Bossuyt, Kimberly L Dodge-Kafka, Kenneth S Ginsburg, Donald M Bers
Publikováno v:
Function (Oxford, England), vol 3, iss 3
β-adrenergic receptor (β-AR) signaling in cardiac myocytes is central to cardiac function, but spatiotemporal activation within myocytes is unresolved. In rabbit ventricular myocytes, β-AR agonists or high extracellular [Ca] were applied locally a
Autor:
Tomasz, Boczek, Qian, Yu, Ying, Zhu, Kimberly L, Dodge-Kafka, Jeffrey L, Goldberg, Michael S, Kapiloff
Publikováno v:
eNeuro
The second messenger cyclic adenosine monophosphate (cAMP) is important for the regulation of neuronal structure and function, including neurite extension. A perinuclear cAMP compartment organized by the scaffold protein muscle A-kinase anchoring pro
Autor:
Kimberly L. Dodge-Kafka, Joshua M. Lubner, George M. Church, Cathrine R. Carlson, Michael F. Chou, Daniel Schwartz
Publikováno v:
FEBS Letters. 591:459-467
The PKAL205R hotspot mutation has been implicated in Cushing's syndrome through hyperactive gain-of-function PKA signaling; however, its influence on substrate specificity has not been investigated. Here, we employ the Proteomic Peptide Library (ProP
Publikováno v:
Cell Signal
Striated myocytes compose about half of the cells of the heart, while contributing the majority of the heart's mass and volume. In response to increased demands for pumping power, including in diseases of pressure and volume overload, the contractile
Autor:
Jeffrey L. Goldberg, Tomasz Boczek, Kimberly L. Dodge-Kafka, Qian Yu, Michael S. Kapiloff, Ying Zhu
Publikováno v:
eneuro. 8:ENEURO.0298-20.2021
The second messenger cyclic adenosine monophosphate (cAMP) is important for the regulation of neuronal structure and function, including neurite extension. A perinuclear cAMP compartment organized by the scaffold protein muscle A-Kinase Anchoring Pro
Publikováno v:
J Physiol
The ubiquitous Ca2+ /calmodulin-dependent phosphatase calcineurin is a key regulator of pathological cardiac hypertrophy whose therapeutic targeting in heart disease has been elusive due to its role in other essential biological processes. Calcineuri
Autor:
Hrishikesh Thakur, Michael S. Kapiloff, Shania Aponte Paris, Kimberly L. Dodge-Kafka, Jinliang Li
Publikováno v:
The Journal of biological chemistry. 294(7)
Myocyte enhancer factor 2 (MEF2) transcription factors are key regulators of the development and adult phenotype of diverse tissues, including skeletal and cardiac muscles. Controlled by multiple post-translational modifications, MEF2D is an effector
Class IIa histone deacetylases (HDACs) are transcriptional repressors whose nuclear export in the cardiac myocyte is associated with the induction of pathological gene expression and cardiac remodeling. Class IIa HDACs are regulated by multiple, func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6e0775b2f9999a90886158edc1f381
https://europepmc.org/articles/PMC5940533/
https://europepmc.org/articles/PMC5940533/