Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kimberly Kramer-Stickland"'
Publikováno v:
Drug Metabolism Reviews. 32:413-420
Topical application of vitamin E has been shown to decrease the incidence of ultraviolet (UV)-induced skin cancer in mice. Vitamin E provides protection against UV-induced skin photodamage through a combination of antioxidant and UV absorptive proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c59aadfd03fa322a54ed6c5ddaafaa
https://doi.org/10.1081/dmr-100102343
https://doi.org/10.1081/dmr-100102343
Autor:
Boris Gorovits, Carmel M. Lynch, Diann Blanset, Garvin Warner, Kimberly Kramer-Stickland, Paul A. Andrews, Stanley A. Roberts, Kelly Flagella, Pauline L. Martin, Stephane Thibault
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 67(3)
Antibody drug conjugates (ADCs) include monoclonal antibodies that are linked to cytotoxic small molecules. A number of these agents are currently being developed as anti-cancer agents designed to improve the therapeutic index of the cytotoxin (i.e.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc8939a0ed981f14383205e582edbc9
https://pubmed.ncbi.nlm.nih.gov/24012707
https://pubmed.ncbi.nlm.nih.gov/24012707
Autor:
Arthur A. Levin, Tae-Won Kim, Thomas A. Zanardi, Kimberly Kramer-Stickland, Scott P. Henry, Robert A. Fey
Antisense inhibitors continue to mature as integral research tools for understanding biological mechanisms, and have made great progress as therapeutic agents since the last comprehensive reviews in this area were published [1]. Of course, therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f28ef11c1be10d47ec17916678f84e6
https://doi.org/10.1201/9780849387951-20
https://doi.org/10.1201/9780849387951-20
Publikováno v:
Chemical research in toxicology. 12(2)
Topically applied alpha-tocopherol (alpha-TH, vitamin E) inhibits UV-B (290-320 nm) photocarcinogenesis, yet alpha-TH undergoes rapid photooxidation by UV-B in vitro. To examine the effect of UV-B on alpha-TH in vivo, we studied the fate of alpha-TH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bd1ccf7e00d5590b4bdab4222935aa
https://pubmed.ncbi.nlm.nih.gov/10027797
https://pubmed.ncbi.nlm.nih.gov/10027797
Publikováno v:
The Journal of investigative dermatology. 111(2)
We have assessed the hydrolysis of alpha-tocopherol acetate (alpha-TAc) to the active antioxidant alpha-tocopherol (alpha-TH) in mouse epidermis and in supernatant from epidermal homogenates. Topically administered alpha-TH prevents UVB photocarcinog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77adcaa353c45a884e95a8c76ae2ed8d
https://pubmed.ncbi.nlm.nih.gov/9699734
https://pubmed.ncbi.nlm.nih.gov/9699734