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Autor:
Wendy A. Harvey, Kenneth A. Cornell, Xinzhu Pu (Mentor), Cheri L. Lamb, Reilly Clark, Kimberly Jurgensen, Kristen A. Mitchell, Carolyn Klocke
Publikováno v:
Toxicology.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a halogenated aromatic hydrocarbon that elicits toxicity through the aryl hydrocarbon receptor (AhR). In the liver, gross markers of TCDD toxicity are attributed to AhR activation in parenchymal hepatocyt