Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kimberly Jia Yi Low"'
Publikováno v:
Journal of Advanced Research, Vol 36, Iss , Pp 113-132 (2022)
Introduction: Protein aggregation and deposition of uniformly arranged amyloid fibrils in the form of plaques or amorphous aggregates is characteristic of amyloid diseases. The accumulation and deposition of proteins result in toxicity and cause dele
Externí odkaz:
https://doaj.org/article/7fd1a5f07e38414794e007b9d8666318
Autor:
Bhargy Sharma, Joanes Grandjean, Margaret Phillips, Ambrish Kumar, Francesca Mandino, Ling Yun Yeow, Kimberly Jia Yi Low, Vikas Nandwana, Vinayak P. Dravid, Xing Bengang, Sierin Lim, Konstantin Pervushin
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 11, Pp n/a-n/a (2021)
With a significant proportion of the global population growing older (>60 years), the low success rates of current diagnoses for early neurodegeneration signs are disappointing. Early detection of Alzheimer's disease (AD) can improve acclimatization
Externí odkaz:
https://doaj.org/article/c97eb6ddadf94a1ca6e1e77964ae3582
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Anticholinergic drugs can be used as a treatment for many diseases. However, anticholinergic drugs are also known for their cognition-related side effects. Recently, there has been an increasing number of reports indicating a positive association bet
Externí odkaz:
https://doaj.org/article/25e30dded29c4d78a70017fd3054e589
Publikováno v:
Journal of Advanced Research, Vol 36, Iss, Pp 113-132 (2022)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Highlights • Importance of disaggregation mechanism and innate disaggregation in living systems. • Different types and mechanism of disaggregation reported in literature. • Structural details of the interactions and the
Highlights • Importance of disaggregation mechanism and innate disaggregation in living systems. • Different types and mechanism of disaggregation reported in literature. • Structural details of the interactions and the
Autor:
Yuguang Mu, Kimberly Jia Yi Low, Chandra S. Verma, Ali Miserez, Jessica Lim, Akshita Kumar, Konstantin Pervushin
Publikováno v:
The Journal of Physical Chemistry B. 125:6776-6790
The increasing realization of the prevalence of liquid-liquid phase separation (LLPS) across multiple length scales of biological constructs, from intracellular membraneless organelles to extracellular load-bearing tissues, has raised intriguing ques
Autor:
Xing Bengang, Margaret Phillips, Ambrish Kumar, Vinayak P. Dravid, Konstantin Pervushin, Francesca Mandino, Joanes Grandjean, Ling Yun Yeow, Sierin Lim, Kimberly Jia Yi Low, Bhargy Sharma, Vikas Nandwana
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 11, Pp n/a-n/a (2021)
With a significant proportion of the global population growing older (>60 years), the low success rates of current diagnoses for early neurodegeneration signs are disappointing. Early detection of Alzheimer's disease (AD) can improve acclimatization
Autor:
Ali Miserez, Kannaian B, Alag R, Venkatraman A, Philips M, Gabryelczyk B, Kimberly Jia Yi Low, Markus Linder, Konstantin Pervushin
Studying pathogenic effects of amyloids requires homogeneous amyloidogenic peptide samples. Recombinant production of these peptides is challenging due to their susceptibility to aggregation and chemical modifications. Thus, chemical synthesis is pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2448d61cd74ecc46f48d55b8bfdfc67
https://doi.org/10.1101/2021.05.14.443401
https://doi.org/10.1101/2021.05.14.443401
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
Anticholinergic drugs can be used as a treatment for many diseases. However, anticholinergic drugs are also known for their cognition-related side effects. Recently, there has been an increasing number of reports indicating a positive association bet