Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kimberly J. Sipe"'
Publikováno v:
Molecular Brain Research. 128:160-169
Excessive stimulation of the NMDA receptor by glutamate induces cell death and has been implicated in the development of several neurodegenerative diseases. While apoptosis plays a role in glutamate-mediated toxicity, the mechanisms underlying this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b50996fa4117cf35f1bc7993f44711
https://doi.org/10.1016/j.molbrainres.2004.06.011
https://doi.org/10.1016/j.molbrainres.2004.06.011
Publikováno v:
Endocrinology. 143:1362-1370
Hippocampal glucocorticoid receptors (GRs) are believed to play a major role in age-related cognitive decline and cellular vulnerability. It has been proposed that these receptors mediate damaging effects of elevated glucocorticoid secretion on cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee8c7d7e2fd7744483717b58e7df42e
https://doi.org/10.1210/endo.143.4.8740
https://doi.org/10.1210/endo.143.4.8740
Publikováno v:
Molecular Brain Research. 62:111-121
We previously demonstrated TNF toxicity, at high TNF doses or in the presence of actinomycin D, in the N1E-115 neuronal cell line (N1Es), which expresses only the 55 kDa TNF receptor (TNFR). To determine whether presence of the 75 kDa TNFR increases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f057f1e34878d9f1af50fe22676e820
https://doi.org/10.1016/s0169-328x(98)00221-6
https://doi.org/10.1016/s0169-328x(98)00221-6
Publikováno v:
Brain research. Molecular brain research. 38(2)
Tumor necrosis factor-alpha (TNF) is associated with developmental and injury-related events in the central nervous system (CNS). In the present study, we have examined the role of TNF on neurons using the clonal murine neuroblastoma line, N1E-115 (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73504966ad9694c59af597ea9883d13d
https://pubmed.ncbi.nlm.nih.gov/8793110
https://pubmed.ncbi.nlm.nih.gov/8793110