Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kimberly J. Dougherty"'
Autor:
D. Leonardo Garcia-Ramirez, Shayna Singh, Jenna R. McGrath, Ngoc T. Ha, Kimberly J. Dougherty
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Spinal cord neurons integrate sensory and descending information to produce motor output. The expression of transcription factors has been used to dissect out the neuronal components of circuits underlying behaviors. However, most of the canonical po
Externí odkaz:
https://doaj.org/article/bb354c995e034efcaa8556f83b5b97eb
Neural Interactions in Developing Rhythmogenic Spinal Networks: Insights From Computational Modeling
Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
The mechanisms involved in generation of rhythmic locomotor activity in the mammalian spinal cord remain poorly understood. These mechanisms supposedly rely on both intrinsic properties of constituting neurons and interactions between them. A subset
Externí odkaz:
https://doaj.org/article/ccb111d1645c469cab645739e9f1e09d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Central pattern generators (CPGs) in the thoracolumbar spinal cord generate the basic hindlimb locomotor pattern. The locomotor CPG integrates descending commands and sensory information from the periphery to activate, modulate and halt the rhythmic
Externí odkaz:
https://doaj.org/article/459d9507690d4fe1bf2c0210a2f6c2c9
Autor:
Han Zhang, Natalia A Shevtsova, Dylan Deska-Gauthier, Colin Mackay, Kimberly J Dougherty, Simon M Danner, Ying Zhang, Ilya A Rybak
Publikováno v:
eLife, Vol 11 (2022)
Speed-dependent interlimb coordination allows animals to maintain stable locomotion under different circumstances. The V3 neurons are known to be involved in interlimb coordination. We previously modeled the locomotor spinal circuitry controlling int
Externí odkaz:
https://doaj.org/article/42d61dd4982246aeafa0423e47279086
Autor:
Ngoc T Ha, Kimberly J Dougherty
Publikováno v:
eLife, Vol 7 (2018)
Neuronal networks generating hindlimb locomotion are located in the spinal cord. The mechanisms underlying spinal rhythmogenesis are unknown but network activity and interconnectivity of excitatory interneurons likely play prominent roles. Here, we i
Externí odkaz:
https://doaj.org/article/3aaa98380d854b198104bc4f9a18f5b7
Autor:
Victoria E. Abraira, Miriam Aceves, Claudia Angeli, Cynthia M. Arokiaraj, Derin Birch, Manon Bohic, Andrey P. Borisyuk, Jessica C. Butts, Bo Chen, Steven A. Crone, Jaclyn H. DeFinis, Kimberly J. Dougherty, Jennifer N. Dulin, V. Reggie Edgerton, Leonardo D. Garcia-Ramirez, Yury Gerasimenko, Simon F. Giszter, Mark A. Gradwell, Ngoc T.B. Ha, Susan Harkema, Zhigang He, Shaoping Hou, Stephanie C. Koch, Michael A. Lane, Suh Jin Lee, Ariel J. Levine, Erik Z. Li, David S.K. Magnuson, Amr A. Mahrous, Felicia M. Michael, Myung-chul Noh, Bau Pham, Patricia E. Phelps, Alexander G. Rabchevsky, Margo L. Randelman, Shelly Sakiyama-Elbert, Alfredo Sandoval, Rebecca P. Seal, Owen Shelton, Trevor S. Smith, Alexa Marie Tierno, Ashley Tucker, Vicki Tysseling, Nicholas White, Lyandysha V. Zholudeva
Publikováno v:
Spinal Interneurons ISBN: 9780128192603
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1025ce3991afb746e26bcd386fb89beb
https://doi.org/10.1016/b978-0-12-819260-3.01002-7
https://doi.org/10.1016/b978-0-12-819260-3.01002-7
Publikováno v:
Spinal Interneurons ISBN: 9780128192603
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db7881b0c4686bbf08c764247b673c2d
https://doi.org/10.1016/b978-0-12-819260-3.00009-3
https://doi.org/10.1016/b978-0-12-819260-3.00009-3
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5541
We describe and analyze a computational model of neural circuits in the mammalian spinal cord responsible for generating and shaping locomotor-like oscillations. The model represents interacting populations of spinal neurons, including the neurons th
Autor:
Simon M. Danner, Colin MacKay, Dylan Deska-Gauthier, Ying Zhang, Han Zhang, Ilya A. Rybak, Natalia A. Shevtsova, Kimberly J. Dougherty
Publikováno v:
eLife. 11
Speed-dependent interlimb coordination allows animals to maintain stable locomotion under different circumstances. The V3 neurons are known to be involved in interlimb coordination. We previously modeled the locomotor spinal circuitry controlling int