Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kimberly J Dunham-Snary"'
Autor:
Austin D. Read, Rachel E. T. Bentley, Ashley Y. Martin, Jeffrey D. Mewburn, Elahe Alizadeh, Danchen Wu, Patricia D. A. Lima, Kimberly J. Dunham‐Snary, Bernard Thébaud, Willard Sharp, Stephen L. Archer
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 13 (2023)
Background As partial pressure of oxygen (pO2) rises with the first breath, the ductus arteriosus (DA) constricts, diverting blood flow to the pulmonary circulation. The DA's O2 sensor resides within smooth muscle cells. The DA smooth muscle cells’
Externí odkaz:
https://doaj.org/article/e030b967cfd24d6397635a590b09f624
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Introduction Medium‐Chain Acyl‐CoA Dehydrogenase Deficiency (MCADD) is the most common inherited metabolic disorder of β‐oxidation. Patients with MCADD present with hypoketotic hypoglycemia, which may quickly progress to lethargy, com
Externí odkaz:
https://doaj.org/article/0d5e678480bd4bb4a81b11f00c354540
Autor:
Stephen L. Archer, Asish Dasgupta, Kuang-Hueih Chen, Danchen Wu, Kaushal Baid, John E. Mamatis, Victoria Gonzalez, Austin Read, Rachel ET. Bentley, Ashley Y. Martin, Jeffrey D. Mewburn, Kimberly J. Dunham-Snary, Gerald A. Evans, Gary Levy, Oliver Jones, Ruaa Al-Qazazi, Brooke Ring, Elahe Alizadeh, Charles CT. Hindmarch, Jenna Rossi, Patricia DA. Lima, Darryl Falzarano, Arinjay Banerjee, Che C. Colpitts
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102508- (2022)
Rationale: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 pneumonia. We hypothesize that SARS-CoV-2 causes alveolar injury and hypoxemia by damaging mitochondria in airway epithelial cells (AEC) and pulmonary artery smoo
Externí odkaz:
https://doaj.org/article/e159da1d54f348208fca210ce85dc53f
Autor:
Kimberly J. Dunham-Snary, Bas GJ. Surewaard, Jeffrey D. Mewburn, Rachel ET. Bentley, Ashley Y. Martin, Oliver Jones, Ruaa Al-Qazazi, Patricia AD. Lima, Paul Kubes, Stephen L. Archer
Publikováno v:
Redox Biology, Vol 49, Iss , Pp 102225- (2022)
Background: Neutrophils play a role in innate immunity and are critical for clearance of Staphylococcus aureus. Current understanding of neutrophil bactericidal effects is that NADPH oxidase produces reactive oxygen species (ROS), mediating bacterial
Externí odkaz:
https://doaj.org/article/c6180755b5904ae7b1e5168555395369
Autor:
Rachel E.T. Bentley, Charles C.T. Hindmarch, Kimberly J. Dunham-Snary, Brooke Snetsinger, Jeffrey D. Mewburn, Arthur Thébaud, Patricia D.A. Lima, Bernard Thébaud, Stephen L. Archer
Publikováno v:
Data in Brief, Vol 40, Iss , Pp 107736- (2022)
The Ductus Arteriosus (DA) is a fetal vessel that connects the aorta to the pulmonary artery ensuring that placental oxygenated blood is diverted from the lungs to the systemic circulation. Following exposure to oxygen (O2), in the first few days of
Externí odkaz:
https://doaj.org/article/04185031aa114efe97edd725190351e2
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102164- (2021)
Iron-sulfur (Fe–S) clusters are essential cofactors most commonly known for their role mediating electron transfer within the mitochondrial respiratory chain. The Fe–S cluster pathways that function within the respiratory complexes are highly con
Externí odkaz:
https://doaj.org/article/9189ac257478442583ddf540769603f7
Autor:
Kimberly J. Dunham-Snary, Michael W. Sandel, Melissa J. Sammy, David G. Westbrook, Rui Xiao, Ryan J. McMonigle, William F. Ratcliffe, Arthur Penn, Martin E. Young, Scott W. Ballinger
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 316-328 (2018)
We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet. Because it is not feasible to directly test these predictions in humans we used Mito
Externí odkaz:
https://doaj.org/article/e4114c8839ad456c862a8be8c1edabf0
Autor:
Ping Yu Xiong, Lian Tian, Kimberly J. Dunham-Snary, Kuang-Hueih Chen, Jeffrey D. Mewburn, Monica Neuber-Hess, Ashley Martin, Asish Dasgupta, Francois Potus, Stephen L. Archer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2019)
Introduction: Group 2 pulmonary hypertension (PH), defined as a mean pulmonary arterial pressure ≥25 mmHg with elevated pulmonary capillary wedge pressure >15 mmHg, has no approved therapy and patients often die from right ventricular failure (RVF)
Externí odkaz:
https://doaj.org/article/a16e88c2eeca4250a705d66bd834b54e
Autor:
Adrienne L. King, Sudheer K. Mantena, Kelly K. Andringa, Telisha Millender-Swain, Kimberly J. Dunham-Snary, Claudia R. Oliva, Corinne E. Griguer, Shannon M. Bailey
Publikováno v:
Redox Biology, Vol 9, Iss C, Pp 188-197 (2016)
Background: Mitochondrial dysfunction and bioenergetic stress play an important role in the etiology of alcoholic liver disease. Previous studies from our laboratory show that the primary methyl donor S-Adenosylmethionine (SAM) minimizes alcohol-indu
Externí odkaz:
https://doaj.org/article/5cc5bb82c21f45a5b63d4abb58a17931
Autor:
Brooke Snetsinger, Rachel Bentley, Jeffrey Mewburn, Stephen L. Archer, Kimberly J. Dunham-Snary, Patricia D.A. Lima, Arthur Thebaud, Charles C.T. Hindmarch, Bernard Thébaud
Publikováno v:
Genomics. 113:3128-3140
The ductus arteriosus (DA) connects the fetal pulmonary artery and aorta, diverting placentally oxygenated blood from the developing lungs to the systemic circulation. The DA constricts in response to increases in oxygen (O2) with the first breaths,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda7f18e481e312574c268e7bb8a0f67
https://doi.org/10.1016/j.ygeno.2021.07.006
https://doi.org/10.1016/j.ygeno.2021.07.006