Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kimberly Fung"'
Autor:
Outi Keinänen, Kimberly Fung, Jacob Pourat, Vilma Jallinoja, Delphine Vivier, NagaVara Kishore Pillarsetty, Anu J. Airaksinen, Jason S. Lewis, Brian M. Zeglis, Mirkka Sarparanta
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Background Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient. To date, only a few studies have used short-lived radioisotopes for pret
Externí odkaz:
https://doaj.org/article/0fcf170bc14143cab53aa92849dad3cf
Autor:
Kimberly Fung, Delphine Vivier, Outi Keinänen, Elaheh Khozeimeh Sarbisheh, Eric W. Price, Brian M. Zeglis
Publikováno v:
Molecules, Vol 25, Iss 10, p 2315 (2020)
High expression levels of the tumor-associated antigen MUC1 have been correlated with tumor aggressiveness, poor response to therapy, and poor survival in several tumor types, including breast, pancreatic, and epithelial ovarian cancer. Herein, we re
Externí odkaz:
https://doaj.org/article/7954de6aef7d49319329ba50d13b4848
Autor:
Wan Yin Kimberly Fung
Publikováno v:
Social Transformations in Chinese Societies. 18:46-58
Purpose This paper aims at illustrating how the local and the decentralized temple management bodies were made governable and governed through law. Design/methodology/approach This paper examines the implementation of Chinese Temples Ordinances (the
Autor:
Ellen van Dam, Colin Biggin, Jason S. Lewis, Paul S. Donnelly, James M Brennan, Outi Keinänen, Amos Hedt, Nicholas Zia, Kimberly Fung, Jon Stoner, Matthew P. Harris, Brian M. Zeglis
Publikováno v:
Proceedings of the National Academy of Sciences. 117:28316-28327
Over the past decade, theranostic imaging has emerged as a powerful clinical tool in oncology for identifying patients likely to respond to targeted therapies and for monitoring the response of patients to treatment. Herein, we report a theranostic a
Autor:
Brian M. Zeglis, Kimberly Fung, Kara Long Roche, Jason S. Lewis, Outi Keinänen, Sai Kiran Sharma
Publikováno v:
Mol Pharm
Ovarian cancer is the fifth leading cause of cancer deaths amongst women, accounting for more deaths than any other cancer of the female reproductive system. The foundation of its management consists of cytoreductive surgery (CRS) followed by systemi
Publikováno v:
Social Movement Studies. 21:79-102
Since the Fukushima nuclear accident in 2011 (3/11), Japan has witnessed a nationwide upsurge of antinuclear demonstrations as well as protests against diverse concerns. Why did this upsurge of pro...
Autor:
Kimberly Fung, Sai Kiran Sharma, Cindy Rodriguez, Gary A. Ulaner, Pierre Adumeau, Jason S. Lewis, Brian M. Zeglis, Delphine Vivier
Publikováno v:
Theranostics. 10:1746-1757
Rationale: The overwhelming majority of radioimmunoconjugates are produced via random conjugation methods predicated on attaching bifunctional chelators to the lysines of antibodies. However, this approach inevitably produces poorly defined and heter
Autor:
Kathryn M. Tully, Jason S. Lewis, Kimberly Fung, Outi Keinänen, Rosemery Membreno, Brian M. Zeglis, Brendon E. Cook
Publikováno v:
Molecular Pharmaceutics. 16:2259-2263
Pretargeted radioimmunotherapy (PRIT) based on the inverse electron demand Diels–Alder reaction has shown promise in murine models of disease, yet the radiation dosimetry of this approach must be optimized to make it a viable clinical option. To th
Publikováno v:
Mol Pharm
Triple negative breast cancer (TNBC) has no targeted detection or treatment method. Mutant p53 (mtp53) is overexpressed in >80% of TNBCs, and the stability of mtp53 compared to the instability of wild-type p53 (wtp53) in normal cells makes mtp53 a pr
Autor:
Outi, Keinänen, Kimberly, Fung, James M, Brennan, Nicholas, Zia, Matt, Harris, Ellen, van Dam, Colin, Biggin, Amos, Hedt, Jon, Stoner, Paul S, Donnelly, Jason S, Lewis, Brian M, Zeglis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Radioimmunotherapy is predicated on harnessing the exquisite specificity of antibodies to deliver cytotoxic radiation to tumors. Yet the long circulation time of radioimmunoconjugates leads to high radiation doses to healthy tissues. Pre