Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kimberly E. Roche"'
Autor:
Kimberly E. Roche, Marvin Weinstein, Leland J. Dunwoodie, William L. Poehlman, Frank A. Feltus
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract We applied two state-of-the-art, knowledge independent data-mining methods – Dynamic Quantum Clustering (DQC) and t-Distributed Stochastic Neighbor Embedding (t-SNE) – to data from The Cancer Genome Atlas (TCGA). We showed that the RNA e
Externí odkaz:
https://doaj.org/article/5df7caa6fa724781984fe8b965d77763
Autor:
Stephen P. Ficklin, Leland J. Dunwoodie, William L. Poehlman, Christopher Watson, Kimberly E. Roche, F. Alex Feltus
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract A gene co-expression network (GCN) describes associations between genes and points to genetic coordination of biochemical pathways. However, genetic correlations in a GCN are only detectable if they are present in the sampled conditions. Wit
Externí odkaz:
https://doaj.org/article/4cac819eb2434b86901fb10baff65daf
Autor:
Kimberly E Roche, Johannes R Bjork, Mauna R Dasari, Laura Grieneisen, David Jansen, Trevor J Gould, Laurence R Gesquiere, Luis B Barreiro, Susan C Alberts, Ran Blekhman, Jack A Gilbert, Jenny Tung, Sayan Mukherjee, Elizabeth A Archie
Publikováno v:
eLife, Vol 12 (2023)
Ecological relationships between bacteria mediate the services that gut microbiomes provide to their hosts. Knowing the overall direction and strength of these relationships is essential to learn how ecology scales up to affect microbiome assembly, d
Externí odkaz:
https://doaj.org/article/e425996b1fbf42978e74518a4aa8d985
Autor:
Kimberly E. Roche, Sayan Mukherjee
Concerns have been raised about the use of relative abundance data derived from next generation sequencing as a proxy for absolute abundances. For example, in the differential abundance setting, compositional effects in relative abundance data may gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ff2a244a74771ec2b2a494b54e4148
https://doi.org/10.1101/2021.12.06.471397
https://doi.org/10.1101/2021.12.06.471397
Autor:
Lauren M, Smith, Francis C, Motta, Garima, Chopra, J Kathleen, Moch, Robert R, Nerem, Bree, Cummins, Kimberly E, Roche, Christina M, Kelliher, Adam R, Leman, John, Harer, Tomas, Gedeon, Norman C, Waters, Steven B, Haase
Publikováno v:
Science
The blood-stage infection of the malaria parasite, Plasmodium falciparum, exhibits ts a48-hour developmental cycle that culminates in the synchronous release of parasites from red blood cells, triggering 48-hour fever cycles in the host. This cycle c
Autor:
Frank Alex Feltus, Kimberly E. Roche, Leland J. Dunwoodie, William L. Poehlman, Marvin Weinstein
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
We applied two state-of-the-art, knowledge independent data-mining methods – Dynamic Quantum Clustering (DQC) and t-Distributed Stochastic Neighbor Embedding (t-SNE) – to data from The Cancer Genome Atlas (TCGA). We showed that the RNA expression
Autor:
William L. Poehlman, F. Alex Feltus, Christopher Watson, Leland J. Dunwoodie, Stephen P. Ficklin, Kimberly E. Roche
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
A gene co-expression network (GCN) describes associations between genes and points to genetic coordination of biochemical pathways. However, genetic correlations in a GCN are only detectable if they are present in the sampled conditions. With the inc
Autor:
Kimberly E Roche, Sayan Mukherjee
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010284 (2022)
Concerns have been raised about the use of relative abundance data derived from next generation sequencing as a proxy for absolute abundances. For example, in the differential abundance setting, compositional effects in relative abundance data may gi
Externí odkaz:
https://doaj.org/article/40410ad003034eb295f77e8c91741436