Výsledky vyhledávání - "Kimberly E. Allen"

Data from Randomized Phase II Multicenter Trial of Two Schedules of Lapatinib as First- or Second-Line Monotherapy in Patients with Advanced or Metastatic Non–Small Cell Lung Cancer

Autor: Frances A. Shepherd, Tal Z. Zaks, Lance Leopold, Kimberly E. Allen, Habib Hassani, Michael Smylie, James R. Rigas, Jennifer Garst, Afshin Dowlati, Nevena Damjanov, Joseph Aisner, George R. Blumenschein, Helen J. Ross

Purpose: This randomized phase II study was initially designed to test the activity of two dose schedules of lapatinib (GW572016H), an oral, reversible, dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) and human EGFR-2 (HER2/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46e80103841eec566f7a61b9767a06e
https://doi.org/10.1158/1078-0432.c.6517636.v1

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Supplementary Data from Randomized Phase II Multicenter Trial of Two Schedules of Lapatinib as First- or Second-Line Monotherapy in Patients with Advanced or Metastatic Non–Small Cell Lung Cancer

Supplementary Data from Randomized Phase II Multicenter Trial of Two Schedules of Lapatinib as First- or Second-Line Monotherapy in Patients with Advanced or Metastatic Non–Small Cell Lung Cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd3bdd182ae6ad75ba8f901111516c9
https://doi.org/10.1158/1078-0432.22440286.v1

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Influence of Clothing on Thermoregulation and Comfort During Exercise in the Heat

Autor: Nicola I. Stolworthy, Taylor R. Welch, Jon-Kyle Davis, Kimberly E. Allen, Michael E. Nevett, Yang Zhang, C. Matt Laurent

Publikováno v: Journal of Strength and Conditioning Research. 31:3435-3443

Davis, JK, Laurent, CM, Allen, KE, Zhang, Y, Stolworthy, NI, Welch, TR, and Nevett, ME. Influence of clothing on thermoregulation and comfort during exercise in the heat. J Strength Cond Res 31(12): 3435-3443, 2017-Sport textiles of synthetic fiber h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15742cdd6c902ae65c7ec1447ffc1bdb
https://doi.org/10.1519/jsc.0000000000001754

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Influence of Dehydration on Intermittent Sprint Performance

Autor: Taylor R. Welch, C. Matt Laurent, Nicola I. Stolworthy, J. Matt Green, Jon-Kyle Davis, Kimberly E. Allen, Michael E. Nevett

Publikováno v: Journal of Strength and Conditioning Research. 29:2586-2593

This study examined the effects of dehydration on intermittent sprint performance and perceptual responses. Eight male collegiate baseball players completed intermittent sprints either dehydrated (DEHY) by 3% body mass or euhydrated (EU). Body mass w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b5e6bc7f0df6acd3177976c1287a3f
https://doi.org/10.1519/jsc.0000000000000907

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Randomized Phase II Multicenter Trial of Two Schedules of Lapatinib as First- or Second-Line Monotherapy in Patients with Advanced or Metastatic Non–Small Cell Lung Cancer

Autor: James R. Rigas, Tal Zaks, Nevena Damjanov, Michael Smylie, Habib Hassani, Frances A. Shepherd, Afshin Dowlati, Lance Leopold, Kimberly E. Allen, Joseph Aisner, Helen J. Ross, Jennifer Garst, George R. Blumenschein

Publikováno v: Clinical Cancer Research. 16:1938-1949

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e281f6ed0cfb6d1bf9a938eccdb124b6
https://doi.org/10.1158/1078-0432.ccr-08-3328

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Cardiac Autonomic Response to Handgrip Exercise Performed with and without Blood Flow Restriction

Autor: Daniel P. Credeur, Jeffrey D. Miller, Kimberly E. Allen, Edward T. Kelley

Publikováno v: Medicine & Science in Sports & Exercise. 49:723

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6756b6bd551272254b67bb173bdd1119
https://doi.org/10.1249/01.mss.0000518923.99575.a9

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Does the proliferation of human lymphoma cells depend on the mutation of EZH2 and consequential epigenetic modification of H3K27?

Publikováno v: Epigenomics. 4(3)

Trimethylation of histone H3 on lysine 27 (H3K27me3) is a repressive posttranslational modification mediated by the histone methyltransferase EZH2. EZH2 is a component of the polycomb repressive complex 2 and is overexpressed in many cancers. In B-ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb57900dceb3d73a26fbff84799ac2a6
https://pubmed.ncbi.nlm.nih.gov/22323599

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Frameshift events associated with the lysyl-tRNA and the rare arginine codon, AGA, in Escherichia coli: a case study involving the human Relaxin 2 protein

Autor: Kimberly E. Allen, Quinn Lu, James F. Kane, Kyung O. Johanson, Janice M. Trulli, Matthew C. Burns, Dean E. McNulty, Xiaoyan Tang, John J. Kerrigan

Publikováno v: Protein expression and purification. 60(2)

Human Relaxin 2 is an insulin-related peptide hormone with a mass of 19,084 Da. The mRNA contains a number of arginine codons that are rarely used by Escherichia coli to produce highly expressed proteins. As a result, expressing this recombinant prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e75b801cdd5d08727ef82d3aba5850
https://pubmed.ncbi.nlm.nih.gov/18474430

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Abstract 1057: Mutation of EZH2 A677 in human B-cell lymphoma promotes hyper-trimethylation of H3K27

Publikováno v: Cancer Research. 72:1057-1057

Trimethylation of histone H3 on lysine 27 (H3K27me3) is a repressive post-translational modification mediated by the histone methyltransferase EZH2. EZH2 is a component of the Polycomb Repressive Complex 2 (PRC2) and its expression and catalytic acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e75a3b61849499cb749c8b2b24d49d0
https://doi.org/10.1158/1538-7445.am2012-1057

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