Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kimberly D Leuthner"'
Publikováno v:
Expert Review of Anti-infective Therapy. 13:149-159
In the era of increasing antibiotic resistance, development of new agents that could provide therapeutic options for difficult to treat pathogens is vital. Dalbavancin is a new lipoglycopeptide recently approved by the US FDA for the treatment of acu
Autor:
Gary V. Doern, Kimberly D. Leuthner
Publikováno v:
Journal of Clinical Microbiology. 51:3916-3920
The development of antimicrobial agents represents one of the most significant achievements in medicine during the past century. However, the emergence of antimicrobial resistance combined with the downturn in the development of new antimicrobial age
Publikováno v:
Journal of Pharmacy Practice. 26:506-513
Antimicrobial stewardship programs are essential to health care institutions to promote the appropriate use of antibiotics not only to decrease antimicrobial resistance but to prevent the spread and infection of Clostridium difficile. Clostridium dif
Publikováno v:
Open Forum Infectious Diseases. 3
Autor:
Laura A Puzniak, Ravina Kullar, Kimberly D Leuthner, David A Hewlett, Becky Jayakumar, Truong Nguyen
Publikováno v:
Open Forum Infectious Diseases
Background There is a global increase in Gram-negative (GN) pathogens, with Enterobacteriaceae and Pseudomonas aeruginosa(PSA) being the major threats in clinical practice. C/T is a novel antipseudomonal cephalosporin combined with an established β-
Autor:
Thomas P. Lodise, Marcus J. Zervos, Katherine Reyes, James A. McKinnell, Karri A. Bauer, Romic Eskandarian, Kimberly D Leuthner, Darren L. Culshaw, Joyce Bensman, Annie Wong-Beringer, Saira B. Chaudhry, Winter J. Smith, Kenneth C. Lamp, Robert Adamson, Pamela A. Moise, Michael Virata, Debra A. Goff
Publikováno v:
Clinical therapeutics. 38(1)
Purpose Clinical studies comparing vancomycin with alternative therapy for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia are limited. The objective of this study was to compare outcomes of early daptomycin versus vancomycin treatment
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:1298-1303
We inoculated an in vitro pharmacodynamic model simultaneously with clinical isolates of methicillin-resistant Staphylococcus aureus and an enterocin-producing enterococcus (vancomycin-resistant Enterococcus faecalis , ampicillin susceptible) at 7 lo
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:813-816
We evaluated pulsatile dosing of clarithromycin and amoxicillin alone or combined against Streptococcus pneumoniae with various susceptibilities. When combined, pulsatile amoxicillin with clarithromycin was superior to either 8- or 12-h dosing agains
Publikováno v:
Open Forum Infectious Diseases
Background Mucormycosis (MC) is a group of invasive fungal infections with a mortality rate approaching 100% in disseminated disease. The incidence of MC is low, with one study estimating 500 cases/year in the United States, making optimal treatment
Publikováno v:
Therapeutics and Clinical Risk Management
Acute bacterial skin and skin structure infections (ABSSSI) are a common disease causing patients to seek treatment through the health care system. With the continued increase of drug-resistant bacterial pathogens, these infections are becoming more