Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kimberly D Kyker"'
Autor:
Robert E Hurst, Paul J Hauser, Kimberly D Kyker, Jonathan E Heinlen, Jason P Hodde, Michael C Hiles, Stanley D Kosanke, Mikhail Dozmorov, Michael A Ihnat
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64181 (2013)
A major problem in cancer research is the lack of a tractable model for delayed metastasis. Herein we show that cancer cells suppressed by SISgel, a gel-forming normal ECM material derived from Small Intestine Submucosa (SIS), in flank xenografts sho
Externí odkaz:
https://doaj.org/article/c41542a398374ce6a6bca80616173b65
Publikováno v:
American Journal of Pharmacology and Toxicology. 1:72-78
Bladder cancer recurs in up to 70% of patients judged to be tumor-free after treatment. Like other cancers, delayed appearance of metastases is common. These findings suggest the malignant phenotype can be suppressed, to emerge later. Following up on
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 21:255-261
Elucidating the mechanisms by which the phenotype of cancer cells is modulated by the extracellular matrix (ECM) potentially identifies mechanisms that could be exploited for cancer control. Three readily available bladder cancer cell lines of differ
Publikováno v:
Circulation. 102:2535-2540
Background —G protein–coupled receptor kinases (GRKs) modulate myocardial β-adrenergic receptor (βAR) signaling. We examined whether GRK activity was altered 6, 24, and 96 hours after left anterior descending coronary artery ligation (LAD CAL)
Autor:
Stanley D. Kosanke, Kimberly D. Kyker, Michael C. Hiles, Paul J. Hauser, Michael A. Ihnat, Robert E. Hurst, Mikhail G. Dozmorov, Jason P. Hodde, Jonathan E. Heinlen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64181 (2013)
PLoS ONE
PLoS ONE
A major problem in cancer research is the lack of a tractable model for delayed metastasis. Herein we show that cancer cells suppressed by SISgel, a gel-forming normal ECM material derived from Small Intestine Submucosa (SIS), in flank xenografts sho
Autor:
Ricardo Saban, Michael Centola, Kimberly D. Kyker, Mikhail G. Dozmorov, Robert E. Hurst, Arto S. Baghdayan, Nathan Shankar
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 8, Iss Suppl 7, p S2 (2007)
BMC Bioinformatics, Vol 8, Iss Suppl 7, p S2 (2007)
Background To better understand the response of urinary epithelial (urothelial) cells to Enterococcus faecalis, a uropathogen that exhibits resistance to multiple antibiotics, a genome-wide scan of gene expression was obtained as a time series from u
Autor:
Hiroyuki Matsumoto, Kimberly D. Kyker, Edna Betgovargez, Michael H. Simonian, Robert E. Hurst, Anil Singh, Mikhail G. Dozmorov, Nobuaki Takemori, Ricardo Saban
Publikováno v:
Proteome Science, Vol 4, Iss 1, p 13 (2006)
Proteome Science
Proteome Science
Background The extracellular matrix can have a profound effect upon the phenotype of cancer cells. Previous work has shown that growth of bladder cancer cells on a matrix derived from normal basement membrane suppresses many malignant features that a
Publikováno v:
BMC Urology, Vol 5, Iss 1, p 4 (2005)
BMC Urology
BMC Urology
Background Interstital cystitis is often treated with exogenous glycosaminoglycans such as heparin, chondroitin sulphate (Uracyst), hyaluronate (Cystistat) or the semi-synthetic pentosan polysulphate (Elmiron). The mechanism of action is presumed to
Publikováno v:
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 132(2)
Curcumin, a potential chemopreventive agent, was found to inhibit cancer cells in S/G2M phases of the cell cycle, when radiation is more effective. The purpose of the current study was to investigate whether curcumin can sensitize squamous cell carci
Publikováno v:
Cancer letters. 217(2)
We have previously shown that growth of bladder carcinoma cell lines onto matrices such as Matrigel and small intestinal submucosal (SIS) gel cause distinct changes in cellular morphology and motility. In these studies, we found that bladder cells gr