Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kimberly D Brewer"'
Autor:
Drew R DeBay, Kimberly D Brewer, Sarah A LeBlanc, Genevieve M Weir, Marianne M Stanford, Marc Mansour, Chris V Bowen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
In the preclinical development of immunotherapy candidates, understanding the mechanism of action and determining biomarkers that accurately characterize the induced host immune responses is critical to improving their clinical interpretation. Magnet
Externí odkaz:
https://doaj.org/article/dc2d00fa68ff4ca59c11cf9fa70442ff
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-25 (2023)
Abstract Background The Cubresa Spark is a novel benchtop silicon-photomultiplier (SiPM)-based preclinical SPECT system. SiPMs in SPECT significantly improve resolution and reduce detector size compared to preclinical cameras with photomultiplier tub
Externí odkaz:
https://doaj.org/article/09d3ebb7efb54a8481a53a5c28c422be
Autor:
Marie-Laurence Tremblay, Zoe O’Brien-Moran, James A. Rioux, Andrea Nuschke, Christa Davis, W. Martin Kast, Genevieve Weir, Marianne Stanford, Kimberly D. Brewer
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
DPX is a unique T cell activating formulation that generates robust immune responses (both clinically and preclinically) which can be tailored to various cancers via the use of tumor-specific antigens and adjuvants. While DPX-based immunotherapies ma
Externí odkaz:
https://doaj.org/article/98f81394426d423f8660cda764c482b5
Publikováno v:
Magnetic Resonance Imaging. 79:121-129
Purpose Develop a magnetic resonance fingerprinting (MRF) methodology with R2∗ quantification, intended for use with simultaneous contrast agent concentration mapping, particularly gadolinium (Gd) and iron labelled CD8+ T cells. Methods Variable-de
Autor:
Charles A. Maitz, Robert J. Abraham, David T.L. Liu, George Mawko, Andrew C. Gordon, E Courtney Henry, Matthew Strugari, S. Cheenu Kappadath, Kimberly D. Brewer, Alasdair Syme, Jeffrey N. Bryan
Purpose To perform precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model and to compare extracted dose metrics to those produced from conventional PET-based dosimetry. Materials and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb90c7ac77462a535f0257a53f3aac1
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine. 33:469-481
Tracking the migration of superparamagnetic iron oxide (SPIO)-labeled immune cells in vivo is valuable for understanding the immunogenic response to cancer and therapies. Quantitative cell tracking using TurboSPI-based R2* mapping is a promising deve
Autor:
T.Z. Todorova, J. Gosse, E. Tonkopi, R. A. Manchester, Kimberly D. Brewer, C. Davis, M. Shymka, Daniel Boyd, B. Kelly
Publikováno v:
Discover Materials, Vol 1, Iss 1, Pp 1-8 (2021)
Sixteen borate glass compositions comprising K2O and SrO were screened, using a design of mixtures approach, to model compositional effects on dissolution, CT imageability, and MRI relaxivity (R2). Based on the characteristics of each network, togeth
Autor:
Ellen Parker, Refat Aboghazleh, Griffin Mumby, Ronel Veksler, Jonathan Ofer, Jillian Newton, Rylan Smith, Lyna Kamintsky, Casey M A Jones, Eoin O’Keeffe, Eoin Kelly, Klara Doelle, Isabelle Roach, Lynn T Yang, Pooyan Moradi, Jessica M Lin, Allison J Gleason, Christina Atkinson, Chris Bowen, Kimberly D Brewer, Colin P Doherty, Matthew Campbell, David B Clarke, Gerben van Hameren, Daniela Kaufer, Alon Friedman
Publikováno v:
Brain : a journal of neurology, vol 145, iss 6
Brain
Brain
The mechanisms underlying the complications of mild traumatic brain injury, including post-concussion syndrome, post-impact catastrophic death, and delayed neurodegeneration remain poorly understood. This limited pathophysiological understanding has
Autor:
Marie-Laurence Tremblay, Mark Filiaggi, Kimberly D. Brewer, Jensen Doucet, Andrea Nuschke, Daniel Boyd, Robert J. Abraham, Steven D. Beyea, E. Tonkopi, Ulrike Werner-Zwanziger
Publikováno v:
Journal of Non-Crystalline Solids. 510:26-35
Two glass series were developed based on the substitution of a monovalent glass modifier for a di- or trivalent ion in a high borate glass system. The BRS series consists of compositions 0.70 B2O3–0.30-X Rb2O – X SrO, and the BRG series consists
Autor:
Kimberly D. Brewer, Miriam Hewlett, Chris V. Bowen, Sharon E. Clarke, James A. Rioux, Steven D. Beyea, Christa Davis
Publikováno v:
Nmr in Biomedicine
Nonalcoholic fatty liver disease (NAFLD) is a growing health problem, and a major challenge in NAFLD management is identifying which patients are at risk of progression to more serious disease. Simple measurements of liver fat content are not strong