Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kimberly Bunce"'
Autor:
Tianjiao Chu, Kimberly Bunce, Patricia Shaw, Varsha Shridhar, Andrew Althouse, Carl Hubel, David Peters
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107318 (2014)
A small number of recent reports have suggested that altered placental DNA methylation may be associated with early onset preeclampsia. It is important that further studies be undertaken to confirm and develop these findings. We therefore undertook a
Externí odkaz:
https://doaj.org/article/1ce22b4173b34a309f47c3f4dbf5dbd3
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14723 (2011)
Epigenetics can be loosely defined as the study of cellular "traits" that influence biological phenotype in a fashion that is not dependent on the underlying primary DNA sequence. One setting in which epigenetics is likely to have a profound influenc
Externí odkaz:
https://doaj.org/article/61130343638e4770a1b8bb6a4a8ec00f
Autor:
Liora S. Katz, Patricia Shaw, Carmen Argmann, Tianjiao Chu, David G. Peters, Jun Zhu, Nikolas Dedousis, Donald K. Scott, Lucy Li, Pili Zhang, Ian Sipula, Benjamin S. Mantell, Kimberly Bunce, Robert M. O'Doherty
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 4, Pp 327-339 (2017)
Molecular Metabolism, Vol 6, Iss 4, Pp 327-339 (2017)
Objective Overnutrition can alter gene expression patterns through epigenetic mechanisms that may persist through generations. However, it is less clear if overnutrition, for example a high fat diet, modifies epigenetic control of gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed13478331c5787d22b6c5724c165689
Autor:
Tianjiao Chu, Suveyda Yeniterzi, W. Allen Hogge, David G. Peters, Kimberly Bunce, Patricia Shaw, Aleksander Rajkovic, Mary K. Dunkel
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0171882 (2017)
PloS one, vol 12, iss 3
PLoS ONE
PloS one, vol 12, iss 3
PLoS ONE
Minimally Invasive Karyotyping (MINK) was communicated in 2009 as a novel method for the non-invasive detection of fetal copy number anomalies in maternal plasma DNA. The original manuscript illustrated the potential of MINK using a model system in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f959292bfd5885399ff3619294dc994f
http://europepmc.org/articles/PMC5356998?pdf=render
http://europepmc.org/articles/PMC5356998?pdf=render
Autor:
Suveyda Yeniterzi, Mary K. Dunkel, David G. Peters, Patricia Shaw, Tianjiao Chu, W. Allen Hogge, Aleksandar Rajkovic, Kimberly Bunce
Publikováno v:
Prenatal Diagnosis. 34:469-477
Background/Objective The non-invasive prenatal detection of fetal microdeletions becomes increasingly challenging as the size of the mutation decreases, with current practical lower limits in the range of a few megabases. Our goals were to explore th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502d53d06a22ee8d6f97fcdc2c1cdcb4
https://doi.org/10.1002/pd.4331
https://doi.org/10.1002/pd.4331
Autor:
Patricia Shaw, Mary K. Dunkel, Tianjiao Chu, Suveyda Yeniterzi, Svetlana A. Yatsenko, Kimberly Bunce, David G. Peters
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0153182 (2016)
PLoS ONE, Vol 11, Iss 6, p e0153182 (2016)
Our goal was to test the hypothesis that inter-individual genomic copy number variation in control samples is a confounding factor in the non-invasive prenatal detection of fetal microdeletions via the sequence-based analysis of maternal plasma DNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59db3de7799cb954d16165754c0a672
http://europepmc.org/articles/PMC4889033
http://europepmc.org/articles/PMC4889033
Publikováno v:
Prenatal Diagnosis. 32:542-549
Objectives The primary goal of this study was to identify CpG sites in the human genome that are differentially methylated in DNA obtained from chorionic villus samples (CVS) and gestational age-matched maternal blood cell (MBC) samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4934095011ceeee57f1c6163b53f4911
https://doi.org/10.1002/pd.3853
https://doi.org/10.1002/pd.3853
Autor:
Augustine Rajakumar, Tianjiao Chu, Carl A. Hubel, Kimberly Bunce, Daniel Handley, Brian Burke, David G. Peters, Arundhathi Jeyabalan
Publikováno v:
Placenta. 32:70-78
Preeclampsia is a major obstetrical complication affecting maternal and fetal health. While it is clear that there is a substantial placental contribution to preeclampsia pathogenesis, the maternal contribution is less well characterized. We therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1033fbef228001a59e7a6d0c1dac15bb
https://doi.org/10.1016/j.placenta.2010.10.004
https://doi.org/10.1016/j.placenta.2010.10.004
Publikováno v:
Prenatal Diagnosis. 30:1226-1229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e09caa6a939de40475cd03b6286544b4
https://doi.org/10.1002/pd.2656
https://doi.org/10.1002/pd.2656
Publikováno v:
Bioinformatics. 26:2863-2866
Motivation: A growing body of literature has demonstrated the potential for non-invasive diagnosis of a variety of human genetic diseases using cell-free DNA extracted from maternal plasma samples in early gestation. Such methods are of great signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574f57121722e783f4758c9893f66715
https://doi.org/10.1093/bioinformatics/btq544
https://doi.org/10.1093/bioinformatics/btq544