Výsledky vyhledávání - "Kimberly Brito Tecchio"

Akademický článek

Ortho-nitrobenzyl derivatives as potential anti-schistosomal agents

Autor: Marcela Silva Lopes, Brian Michio Suzuki, Glaécia Aparecida do Nascimento Pereira, Alexandra Christina Probst, Rafaela Salgado Ferreira, Júlia Teixeira de Oliveira, Kimberly Brito Tecchio, Fabio Vieira dos Santos, Conor Robert Caffrey, Renata Barbosa de Oliveira

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 2 (2018)

ABSTRACT In the search for new anti-schistosomal agents, a series of fifteen ortho-nitrobenzyl derivatives was assayed in vitro against both the schistosomulum (somule) and adult forms of Schistosoma mansoni. Compounds 8 and 12 showed significant act

Externí odkaz: https://doaj.org/article/50aaf06e98ec4935a5257ff91ce78640

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In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho-nitrobenzyl derivatives in human cancer cell lines, with and without metabolic activation

Autor: Júlia Teixeira De Oliveira, Kimberly Brito Tecchio, Marcela Silva Lopes, Silmara Nunes Andrade, Rosy Iara Maciel De Azambuja Ribeiro, Fernando De Pilla Varotti, Renata Barbosa De Oliveira, Gustavo Henrique Ribeiro Viana, Vanessa J. Da Silva Vieira Dos Santos, Fabio Vieira Dos Santos

Publikováno v: Drug and Chemical Toxicology. :1-12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14b9f069828d9d5ecd9e75fe9147fa49
https://doi.org/10.1080/01480545.2023.2184478

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Metabolic activation enhances the cytotoxicity, genotoxicity and mutagenicity of two synthetic alkaloids with selective effects against human tumour cell lines

Autor: Filipe Nogueira Franco, Camila de Souza Barbosa, Vanessa J. S. V. Santos, Rosy Iara Maciel de Azambuja Ribeiro, Kimberly Brito Tecchio, Fábio Vieira dos Santos, Gustavo Henrique Ribeiro Viana, Júlia Teixeira de Oliveira, Alessandra Mirtes Marques Neves Gonçalves

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :503294

The pharmacological potential of drugs must be evaluated to establish their potential therapeutic benefits and side effects. This evaluation includes assessment of the effects of hepatic enzymes that catalyse their metabolic activation. Previously, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8491b875797485895f2ab484aeb18707
https://doi.org/10.1016/j.mrgentox.2020.503294

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Ortho-nitrobenzyl derivatives as potential anti-schistosomal agents

Autor: Brian M. Suzuki, Fábio Vieira dos Santos, Conor R. Caffrey, Glaécia Aparecida do Nascimento Pereira, Marcela Silva Lopes, Renata Barbosa de Oliveira, Alexandra Christina Probst, Júlia Teixeira de Oliveira, Kimberly Brito Tecchio, Rafaela Salgado Ferreira

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 2 (2018); e17376
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 2 (2018); e17376
Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 2 (2018); e17376
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 2 (2018)

In the search for new anti-schistosomal agents, a series of fifteen ortho-nitrobenzyl derivatives was assayed in vitro against both the schistosomulum (somule) and adult forms of Schistosoma mansoni. Compounds 8 and 12 showed significant activity aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ecb373453c71552c23af04731c29fc
https://www.revistas.usp.br/bjps/article/view/153797

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